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Citation
Bier, E., Vaessin, H., Shepherd, S., Lee, K., McCall, K., Barbel, S., Ackerman, L., Carretto, R., Uemura, T., Grell, E., Jan, L.Y., Jan, Y.N. (1989). Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.  Genes Dev. 3(): 1273--1287.
FlyBase ID
FBrf0049800
Publication Type
Research paper
Abstract

A P-element vector has been constructed and used to generate lines of flies with single autosomal P-element insertions. The lines were analyzed in two ways: (1) the identification of cis-acting patterning information within the Drosophila genome, as revealed by a lacZ reporter gene within the P element, and (2) the isolation of lethal mutations. We examined 3768 independent lines for the expression of lacZ in embryos and looked among these lines for lethal mutations affecting embryonic neurogenesis. This type of screen appears to be an effective way to find new loci that may play a role in the development of the Drosophila nervous system.

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Genes Dev.
    Title
    Genes & Development
    Publication Year
    1987-
    ISBN/ISSN
    0890-9369
    Data From Reference
    Alleles (43)
    Genes (18)
    Datasets (1)
    Molecular Constructs (4)
    Molecular Segments (6)
    Insertions (41)
    Experimental Tools (2)
    Transgenic Constructs (2)