|
Reference
|
| Citation |
Reaume, A.G., Clark, S.H., Chovnick, A. (1989). Xanthine dehydrogenase is transported to the Drosophila eye. Genetics 123(3): 503--509. |
| FlyBase ID |
FBrf0049907 |
| Type of publication |
Research paper |
| Offprint Available |
Yes |
|
External Crossreferences
|
| PubMed ID |
2513252 |
| PubMed Abstract |
The rosy (ry) locus in Drosophila melanogaster codes for the enzyme xanthine dehydrogenase. Mutants that have no enzyme activity
are characterized by a brownish eye color phenotype reflecting a deficiency in the red eye pigment. This report demonstrates
that enzyme which is synthesized in some tissue other than the eye is transported and sequestered at the eye. Previous studies
find that no leader sequence is associated with this molecule but a peroxisomal targeting sequence has been noted, and the
enzyme has been localized to peroxisomes. This represents a rare example of an enzyme involved in intermediary metabolism
being transported from one tissue to another and may also be the first example of a peroxisomal protein being secreted from
a cell.
|
| Biosis |
89014365 |
| Zoological record |
12600049853 |
Associated Information
|
| Comments |
|
| Text of personal communication |
|
| Associated files |
|
|
Related Publications
|
|
|
|
Also Published As
|
|
|
|
Other Reference Information
|
| Secondary IDs |
|
| Language of publication |
English |
| Additional language(s) of abstract |
|
| ISBN |
|
| Place of publication |
|
|
Published In
|
| Abbreviation |
Genetics |
| Title |
Genetics |
| Authors |
|
| Volume range |
1- |
| Year range |
1916- |
| Page range |
|
| Publisher |
|
| Place of publication |
Austin, TX, etc |
| Language of publication |
English |
| ISBN/ISSN |
0016-6731 |
| CODEN |
GENTAE |
|
Data from Reference
|
| Alleles (4)
|
|
|
| Constructs (1)
|
|
|
| Genes (1)
|
|
|
|
Home