Wustmann, G., Szidonya, J., Taubert, H., Reuter, G. (1989). The genetics of position-effect variegation modifying loci in Drosophila melanogaster. Mol. Gen. Genet. 217(): 520--527.
FlyBase ID
FBrf0050576
Publication Type
Research paper
Abstract
The dose dependent effects of position-effect variegation (PEV) modifying genes were studied in chromosome arms 2L, 2R and 3R. Four groups of PEV modifying genes can be distinguished: haplo-abnormal suppressor and enhancer loci with or without a triplo-effect. Using duplications four triplo-abnormal suppressor and four triplo-abnormal enhancer functions were localized. In two cases we proved that these functions correspond to a converse haplo-abnormal one. Altogether 43 modifier loci were identified. Most of these loci proved not to display significant triplo-effects (35). The group of haplo-abnormal loci with a triplo-effect may represent genes which play an important role in heterochromatin packaging.
