Reference Report

Reference
Citation	Mlodzik, M., Hiromi, Y., Weber, U., Goodman, C.S., Rubin, G.M. (1990). The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates. Cell 60(2): 211--224. (Export to RIS)
FlyBase ID	FBrf0051362
Publication Type	Research paper
PubMed ID	2105166
PubMed Abstract	The Drosophila seven-up (svp) gene was isolated as a lethal insertion in an "enhancer trap" screen. It is expressed and required in photoreceptor cell precursors R1, R3, R4, and R6 during eye development. The absence of svp+ function causes a transformation of these cells toward an R7 cell fate, as judged by morphology and expression of an R7-specific marker. This transformation depends in part on the sevenless gene product. Our results show that svp is involved in control of cell fate during the generation of neuronal diversity. Molecular analysis of svp reveals that it is a member of the steroid receptor gene superfamily and is likely to be a Drosophila homolog of the human transcription factor COUP.
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Secondary IDs	FBrf0049323
Language of Publication	English
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Parent Publication
Publication Type	Journal
Abbreviation	Cell
Title	Cell
Publication Year	1974-
ISBN/ISSN	0092-8674
Data from Reference
Aberrations (5)
	Df(3R)E79 Df(3R)E229 Df(3R)kar3Q Df(3R)kar-H10 Df(3R)T-45
Alleles (7)
	Ecol\lacZ^{ninaE.-252+67.omSMB} Ecol\lacZ^Rh4.PF Ecol\lacZ^svp-3 ry^+t7.2 svp¹ svp² svp³
Constructs (3)
	P{Rh1(-252/+67)-lacZ.omSMB} P{Rh4.1900lacZ} pP{β3/lac-6.0cDI}
Genes (17)
	aur Ecol\lacZ l(3)87Ad l(3)87Ae l(3)87Ba l(3)87Bb l(3)87Bc l(3)87Be l(3)87Bf l(3)87Bh l(3)87Bi l(3)87Bj ninaE Pp1-87B Rh4 ry svp
Insertions (4)
	P{HZ}svp³ P{Rh1(-252/+67)-lacZ.omSMB}1 P{Rh4.1900lacZ}9 P{wD}3