Reference Report

Reference
Citation	Hutter, P., Roote, J., Ashburner, M. (1990). A genetic basis for the inviability of hybrids between sibling species of Drosophila. Genetics 124(): 909--920. (Export to RIS)
FlyBase ID	FBrf0051988
Publication Type	Research paper
PubMed ID	2108905
PubMed Abstract	A mutation of Drosophila melanogaster whose only known effect is the rescue of otherwise lethal interspecific hybrids has been characterized. This mutation, Hmr, maps to 1-31.84 (9D1-9E4). Hmr may be the consequence of a P element insertion. It rescues hybrid males from the cross of D. melanogaster females to males of its three sibling species, D. simulans, D. mauritiana and D. sechellia. This rescue is recessive, since hybrid males that carry both Hmr and a duplication expected to be Hmr+ are not rescued. Hmr also rescues the otherwise inviable female hybrids from the cross of compound-X D. melanogaster females to males of its sibling species. This rescue is also recessive, since a compound-X heterozygous for Hmr does not rescue. Another mutation, discovered on the In(1)AB chromosome of D. melanogaster, is also found to rescue normally inviable species hybrids: unlike Hmr, however, In(1)AB rescues hybrid females from the cross of In(1)AB/Y males to sibling females, as well as hybrid males from the cross of In(1)AB females to sibling males. These data are interpreted on the basis of a model for the genetic basis of hybrid inviability of complementary genes.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Genetics
Title	Genetics
Publication Year	1916-
ISBN/ISSN	0016-6731
Data from Reference
Aberrations (9)
	Df(1)HC133 Df(1)N110 Dp(1;2)v⁺63i Dp(1;2)v⁺65b Dp(1;2)v⁺75d In(1)AB Tp(1;2)v⁺63i Tp(1;2)v⁺65b Tp(1;2)v⁺75d
Alleles (2)
	Hmr¹ Hmr²
Genes (2)
	Hmr ras