Reference Report

Reference
Citation	Frolich, A., Wurgler, F.E. (1990). Genotoxicity of ethyl carbamate in the Drosophila wing spot test: dependence on genotype-controlled metabolic capacity. Mutat. Res. 244(3): 201--208. (Export to RIS)
FlyBase ID	FBrf0052617
Publication Type	Research paper
PubMed ID	2114542
PubMed Abstract	Ethylcarbamate has a clear genotoxic potential in Drosophila melanogaster. In the somatic mutation and recombination test (SMART) it induces, in a dose-dependent manner, single spots as well as twin spots. The twin spots indicate a recombinogenic activity of ethyl carbamate. A strong strain difference demonstrates that the metabolic activation of ethyl carbamate to DNA binding metabolites most probably also in Drosophila involves cytochrome P450-dependent enzyme activities.
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Language of Publication	English
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Parent Publication
Publication Type	Journal
Abbreviation	Mutat. Res.
Title	Mutation Research
Publication Year	1964-
ISBN/ISSN	0027-5107
Data from Reference
Alleles (2)
	flr³ mwh^unspecified
Genes (2)
	flr mwh