Reference Report

Reference
Citation	Kim-Ha, J., Smith, J.L., MacDonald, P.M. (1991). oskar mRNA is localized to the posterior pole of the Drosophila oocyte. Cell 66(1): 23--35. (Export to RIS)
FlyBase ID	FBrf0053359
Publication Type	Research paper
PubMed ID	2070416
PubMed Abstract	Mutants of the maternal posterior-group genes of Drosophila lack posterior body pattern elements and germ cells, both of which form through the action of determinants localized to the posterior pole of the oocyte. We report that transcripts of one of these genes, oskar, become localized to the posterior pole of oocytes shortly after the oocyte begins to differentiate visibly. Analysis of various posterior-group mutants reveals that localization of oskar mRNA is an early step in the posterior localization pathway. In addition, we find that nonsense oskar mutations disrupt osk mRNA localization, while missense oskar mutations do not.
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Language of Publication	English
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Parent Publication
Publication Type	Journal
Abbreviation	Cell
Title	Cell
Publication Year	1974-
ISBN/ISSN	0092-8674
Data from Reference
Aberrations (3)
	Df(3R)p-XT103 Df(3R)p-XT118 In(3R)Scr^Msc
Alleles (23)
	BicD¹ BicD² capu² capu^HK3 nos^L7 osk¹ osk² osk³ osk⁵ osk⁶ osk⁷ osk⁸ osk⁹ osk³³⁶ osk³⁶⁶ osk^+t4.3 osk^unspecified pum¹³ spir¹ spir² stau² vas¹ w^+mC
Constructs (2)
	P{osk⁺S106} pP{osk⁺S106}
Genes (9)
	BicD capu nos osk pum spir stau vas w
Insertions (1)
	P{osk⁺S106}C106