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Citation
St. Johnston, R.D., Beuchle, D., Nusslein-Volhard, C. (1991). staufen, a gene required to localize maternal RNAs in the Drosophila egg.  Cell 66(1): 51--63.
FlyBase ID
FBrf0053380
Publication Type
Research paper
Abstract

The posterior group gene staufen is required both for the localization of maternal determinants to the posterior pole of the Drosophila egg and for bicoid RNA to localize correctly to the anterior pole. We report the cloning and sequencing of staufen and show that staufen protein is one of the first molecules to localize to the posterior pole of the oocyte, perhaps in association with oskar RNA. Once localized, staufen is found in the polar granules and is required to hold other polar granule components at the posterior pole. By the time the egg is laid, staufen protein is also concentrated at the anterior pole, in the same region as bicoid RNA.

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Related Publication(s)
Review

Monitor.
Anonymous, 1991, Trends Genet. 7(10): 313 [FBrf0099102]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Aberrations (3)
    Alleles (30)
    Genes (12)
    Insertions (1)
    Transgenic Constructs (1)