Simcox, A.A., Hersperger, E., Shearn, A., Whittle, J.R.S., Cohen, S.M. (1991). Establishment of imaginal discs and histoblast nests in Drosophila. Mech. Dev. 34(): 11--20.
FlyBase ID
FBrf0054605
Publication Type
Research paper
Abstract
In Drosophila the homeotic genes of the bithorax-complex (BX-C) and Antennapedia-complex (ANT-C) specify the identity of segments. Adult segment primordia are established in the embryo as the histoblast nests of the abdomen and the imaginal discs of the head, thorax and terminalia. We have used a molecular probe for the limb primordia and in vivo culture to describe the nature of the adult primordia in mutants in which the pattern of homeotic gene expression was altered. The results suggest that the histoblast or disc 'mode' of development is initiated by the extended germ band stage through activity of the BX-C and ANT-C and is relatively inflexible thereafter [corrected].
