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Reference Report
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| Citation | Matsuzaki, F., Koizumi, K., Hama, C., Yoshioka, T., Nabeshima, Y. (1992). Cloning of the Drosophila prospero gene and its expression in ganglion mother cells. Biochem. Biophys. Res. Commun. 182(3): 1326--1332. (Export to RIS) | ||
| FlyBase ID | FBrf0055443 | ||
| Publication Type | Research paper | ||
| PubMed ID | 1540176 | ||
| PubMed Abstract | The Drosophila central nervous system comprises an enormous diversity of neurons that are originated from neuronal stem cells, neuroblasts. They generate a specific series of ganglion mother cells, each of which is once cleaved into a pair of neurons. Among genes known to control neurogenesis, prospero (pros) was recently identified as a gene required for gene expression specifying properties of some identified neurons. Here we report that pros encodes a nuclear protein containing a homeodomain-like sequence. In neuronal lineages of the central nervous system, pros protein is specifically detected in ganglion mother cells, although their parental neuroblasts have begun expressing a significant level of pros transcripts, suggesting a post-transcriptional control of pros expression. Our results provoke that in neuronal cell differentiation ganglion mother cells might play a pivotal role associating with the pros function. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Biochem. Biophys. Res. Commun. | ||
| Title | Biochemical and Biophysical Research Communications | ||
| Publication Year | 1959- | ||
| ISBN/ISSN | 0006-291X | ||
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Data from Reference
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| Alleles (4)
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| Genes (10)
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| Insertions (2)
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