|Citation||Schuster, C.M., Ultsch, A., Schmitt, B., Betz, H. (1993). Molecular analysis of Drosophila glutamate receptors. Pichon, 1993 : 234--240. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||Insects and other invertebrates use L-glutamate as a neurotransmitter in the central nervous system and at the neuromuscular junction. In contrast to the well-studied effects of L-glutamate on invertebrate muscle cells, relatively little is known about the physiological role of glutamate receptors (GluRs) in the invertebrate central nervous system. We have applied a molecular cloning approach to elucidate the molecular structure of neuronal and muscle-specific Drosophila glutamate receptor subunits (DGluRs). Several domains conserved between rat GluR subunits and DGluRs indicate regions of high functional significance. Drosophila genetics may now be used as a valuable experimental tool to gain further insight into the role of DGluRs in development, synaptic plasticity and control of gene expression.|
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|Language of Publication||English|
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|Also Published As|
|Title||Comparitive molecular neurobiology.|
|Data from Reference|