Reference Report

Reference
Citation	Higson, T.S., Tessiatore, J.E., Bennett, S.A., Derk, R.C., Kotarski, M.A. (1993). The molecular organization of the Star/asteroid region, a region necessary for proper eye development in Drosophila melanogaster. Genome 36(2): 356--366.
FlyBase ID	FBrf0058632
Type of publication	Research paper
Offprint Available	No
External Crossreferences
PubMed ID	8390385
PubMed Abstract	The Star/asteroid (S/ast) region of Drosophila melanogaster has been cloned by P element transposon tagging using the snw chromosome as a source of defective P elements. In each mutation examined, the element integrated into the region was a 0.5-kb element from a region proximal to sn and not one of the head-to-head elements from the sn locus. Previously described spontaneous and X-ray induced mutations of S and ast were located on the molecular map by Southern analysis and restriction endonuclease mapping of genomic clones. S mutations are either large deletions of the cloned region or DNA breaks located near the P element insertions that cause ast mutations. Both S and ast mutations reduce the steady-state amounts of a 3.4-kb RNA. The molecular data, together with the phenotypic interactions observed for S and ast alleles, are consistent with the interpretation that S and ast mutations are lesions within the same gene or within genes that are functionally related.
Biosis	97073894
Zoological record
Associated Information
Comments
Text of personal communication
Associated files
Related Publications

Also Published As

Other Reference Information
Secondary IDs
Language of publication	English
Additional language(s) of abstract	French
ISBN
Place of publication
Published In
Abbreviation	Genome
Title	Genome
Authors
Volume range	29-
Year range	1987-
Page range
Publisher	National Research Council Canada
Place of publication	Ottawa
Language of publication	English
ISBN/ISSN	0831-2796
CODEN	GENOE3
Data from Reference
Aberrations (3)
	Df(2L)S3 T(2;3)S^L T(2;4)ast^v
Alleles (23)
	S¹ ast¹ ast^B612 ast^K11 ast^K12 ast^K13 ast^K14 ast^K15 ast^K16 ast^K17 ast^K18 ast^K19 ast^K20 ast^K21 ast^K2 ast^K3 ast^K5 ast^K6 ast^K6e3 ast^K6r6 ast^K6r7 ast^K7 ast^K9
Genes (2)
	S ast
Insertions (18)
	P{}ast^B612 P{}ast^K11 P{}ast^K12 P{}ast^K13 P{}ast^K14 P{}ast^K15 P{}ast^K16 P{}ast^K17 P{}ast^K18 P{}ast^K19 P{}ast^K20 P{}ast^K21 P{}ast^K2 P{}ast^K3 P{}ast^K5 P{}ast^K6 P{}ast^K7 P{}ast^K9