Reference Report

Reference
Citation	Ellis, M.C., O'Neill, E.M., Rubin, G.M. (1993). Expression of Drosophila glass protein and evidence for negative regulation of its activity in non-neuronal cells by another DNA-binding protein. Development 119(3): 855--865. (Export to RIS)
FlyBase ID	FBrf0065382
Publication Type	Research paper
PubMed ID	8187644
PubMed Abstract	The glass gene encodes a DNA-binding zinc-finger protein required for the development of Drosophila photoreceptor cells and which appears to regulate a number of genes specifically expressed in photoreceptors. We have generated monoclonal antibodies to Glass and used them to examine Glass distribution during development. Glass is expressed in all cell types of the developing eye and in all other organs that contain photoreceptor cells in Drosophila, including a small number of cells in the brain. We altered the normal pattern of glass expression by placing the gene under the control of the hsp70 promoter. Our results suggest that nonphotoreceptor cells are restricted in their response to Glass expression. In an effort to discover the mechanism of this restriction, we examined the expression of a number of reporter gene constructs. Our results suggest that nonsensory cells are unable to express certain reporter constructs in response to Glass expression because another DNA-binding factor represses Glass activity in nonsensory cells.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Development
Title	Development
Publication Year	1987-
ISBN/ISSN	0950-1991
Data from Reference
Alleles (9)
	Ecol\lacZ^GMR.29-1 Ecol\lacZ^{GMR.29-2.T:Zzzz\nls1} Ecol\lacZ^{GMR.38-2.T:Zzzz\nls1} Ecol\lacZ^{GMR.38-2M1.T:Zzzz\nls1} Ecol\lacZ^{GMR.38-2M2.T:Zzzz\nls1} Ecol\lacZ^GMR.C.hs gl^hs.PE ry^+t7.2 w^+mW.hs
Constructs (16)
	P{GMR-lacZ.29-1} P{GMR-lacZ.29-2} P{GMR-lacZ.38-2} P{GMR-lacZ.38-2M1} P{GMR-lacZ.38-2M2} P{GMR-lacZ.C(38.1)} P{hsgl} P{pwnβE} pP{29-1} pP{29-2} pP{38-2} pP{38-2M1} pP{38-2M2} pP{GMR-lacZ.C(38.1)} pP{hsgl} pP{pwnβE}
Genes (7)
	chp Ecol\lacZ gl ninaE ry T:Zzzz\nls1 w