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Citation
Ferveur, J.F., Stortkuhl, K.F., Stocker, R.F., Greenspan, R.J. (1995). Genetic feminization of brain structures and changed sexual orientation in male Drosophila.  Science 267(5199): 902--905.
FlyBase ID
FBrf0080018
Publication Type
Research paper
Abstract

The neural basis of sexual orientation in Drosophila was studied by the production of males with regionally feminized brains. Such flies express the female form of the sex determination gene transformer in a limited number of neurons under the control of GAL4 enhancer trap inserts. This method facilitated the creation of lines with a stable pattern of feminization. In tests of sexual preferences, flies that were feminized in a portion of the antennal lobes or in a subset of the corpora pedunculata (mushroom bodies) courted both males and females. These two brain structures, both of which are involved in olfactory processing, may function in the recognition of sex-specific pheromones, in the control of sex-specific behaviors, or both.

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Note

Bisexual fruit flies point to brain courtship centers.
Barinaga, 1995, Science 267(5199): 791--792 [FBrf0079879]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Science
    Title
    Science
    Publication Year
    1895-
    ISBN/ISSN
    0036-8075
    Data From Reference
    Alleles (13)
    Genes (4)
    Molecular Constructs (1)
    Insertions (10)
    Experimental Tools (1)
    Transgenic Constructs (3)