Reference Report

Reference
Citation	Kawai, K., Furukawa, H., Hirono, I. (1995). Genotoxic activity in vivo of the naturally occurring glucoside, cycasin, in the Drosophila wing spot test. Mutat. Res. 346(3): 145--149. (Export to RIS)
FlyBase ID	FBrf0080151
Publication Type	Research paper
PubMed ID	7700278
PubMed Abstract	Cycasin, methylazoxymethanol-beta-glucoside, is a naturally occurring carcinogenic compound. The genotoxicity of cycasin was assayed in the Drosophila wing spot test. Cycasin induced small single and large single spots on feeding at 10 mumol/g medium. The presence of these spots indicates that cycasin is genotoxic in Drosophila melanogaster. Microorganisms which showed beta-glucosidase activity for cleaving cycasin to toxic aglycon were isolated from gut flora of the Drosophila larvae. Consequently, the Drosophila wing spot test would be useful for mutagenicity screening of other naturally occurring glucosides.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Mutat. Res.
Title	Mutation Research
Publication Year	1964-
ISBN/ISSN	0027-5107
Data from Reference
Alleles (2)
	flr³ mwh^unspecified
Genes (2)
	flr mwh