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de Celis, J.F., Llimargas, M., Casanova, J. (1995). ventral veinless, the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster.  Development 121(10): 3405--3416.
FlyBase ID
FBrf0084541
Publication Type
Research paper
Abstract
The ventral veinless gene (vvl) encodes the previously identified Cf1a protein, a transcription factor containing a POU-domain. During embryonic development vvl function is required for the formation of the tracheal tree and in the patterning of the ventral ectoderm. During imaginal development vvl is required for cell proliferation and the differentiation of the wing veins. vvl expression is restricted to the regions where its function is required, and is dependent on the coordinate activities of signalling molecules such as decapentaplegic, wingless and hedgehog. vvl interacts with other genes involved in vein differentiation, including veinlet, thick veins, torpedo, decapentaplegic and Notch suggesting that vvl function may affect several cell-to-cell communication pathways. We propose that the gene vvl integrates information from different signalling molecules and regulates the expression of specific cell differentiation genes during tracheal development and vein differentiation.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Development
    Title
    Development
    Publication Year
    1987-
    ISBN/ISSN
    0950-1991
    Data From Reference
    Aberrations (2)
    Alleles (20)
    Balancers (2)
    Genes (12)
    Insertions (3)
    Transgenic Constructs (2)