Open Close
Reference
Citation
Gateff, E., Kurzik-Dumke, U., Wismar, J., Löffler, T., Habtemichael, N., Konrad, L., Dreschers, S., Kaiser, S., Protin, U. (1996). Drosophila differentiation genes instrumental in tumor suppression.  Int. J. Dev. Biol. 40(1): 149--156.
FlyBase ID
FBrf0088137
Publication Type
Research paper
Abstract

Tumor suppressor genes of Drosophila are developmental genes which, in the homozygously mutated state, induce in one step malignant or benign neoplastic transformation of specific cell types. They act early in development and by this set the stage for cell specific differentiation of imaginal discs, adult optic neuroblasts, blood and gonial cells. The structure, expression and possible function of the following four tumor suppressor genes are discussed: tumorous imaginal disc, lethal (3) malignant brain tumor, lethal (3) malignant blood neoplasm-1 and benign (2) gonial cell neoplasm.

PubMed ID
PubMed Central ID
DOI
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Int. J. Dev. Biol.
    Title
    International Journal of Developmental Biology
    Publication Year
    1989-
    ISBN/ISSN
    0214-6282
    Data From Reference
    Aberrations (2)
    Alleles (1)
    Genes (9)