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Citation
Schmidt, A., Hollman, M., Schäfer, U. (1996). A newly identified Minute locus, M(2)32D, encodes the ribosomal protein L9 in Drosophila melanogaster.  Mol. Gen. Genet. 251(3): 381--387.
FlyBase ID
FBrf0088926
Publication Type
Research paper
Abstract

A gene encoding a ubiquitously expressed mRNA in Drosophila melanogaster was isolated and identified as the gene for ribosomal protein L9 (rpL9) by its extensive sequence homology to the corresponding gene from rat. The rpL9 gene is localized in polytene region 32D where two independent P element insertions flanking the locus are available. Remobilization of either P element generated lines with a typical Minute phenotype, e.g. thin and short bristles, prolonged development, and female semisterility in heterozygotes as well as homozygous lethality. All these characteristics can be rescued when a 3.9 kb restriction fragment containing the rpL9 gene is reintroduced by P element-mediated germline transformation. This result confirms that M(2)32D codes for ribosomal protein L9.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Mol. Gen. Genet.
    Title
    Molecular and General Genetics
    Publication Year
    1967-2001
    ISBN/ISSN
    0026-8925
    Data From Reference
    Aberrations (5)
    Alleles (7)
    Genes (7)
    Insertions (4)
    Transgenic Constructs (1)
    Transcripts (1)