|Citation||Churikov, N.A. (1996). [The role of retroelements in evolution: an analysis of the suffix element from the Drosophila genome.] Tsitol. Genet. 30(1): 14--22. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||The investigation of sequences homologous to the suffix chains from Drosophila genome revealed the central domain of the element homologous to 16S ribosomal sequence from endosymbiotic organisms. The opposite strand of the element encodes C-domains of reverse transcriptase enzyme in F- and Doc-elements. 19 DNA clones possessing PCR-amplified stretches of genomic DNA were sequenced. It was found that micro-satellite sequences (CAACA)n/(TGTTG)n and (TTTGT)n/(CACAAA)n are the target sites for the insertions of suffix copies in heterochromatic regions of Drosophila genome in both orientations. It was found that the presence of decanucleotide GCGGCCCGGG (GC-box) followed by the alternating stretch (A)5(T)4(A)3(T)2(A)1(T)n (AT-box) led to the fixed polarity of the suffix insertions in the same micro-satellite sequences.|
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|Language of Publication||Russian|
|Additional Languages of Abstract||English and Ukrainian|
|Also Published As|
|Title||Tsitologiia i Genetika|
|Data from Reference|