|Citation||Abu-Issa, R., Cavicchi, S. (1996). Genetic interactions among vestigial, hairy, and Notch suggest a role of vestigial in the differentiation of epidermal and neural cells of the wing and haltere of Drosophila melanogaster. J. Neurogenet. 10(4): 239--246. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||In this paper we describe the results of genetic analysis of the vestigial locus by studying its interactions with hairy and Notch loci in Drosophila melanogaster. Different vestigial alleles in homo- and heterozygous combination with different hairy alleles show synergism in increasing both cell death and formation of ectopic bristles and produce ectopic veins. Interactions between N and vg also show synergism in increasing cell death and formation of ectopic bristles. Only synergism in cell death is seen between h and N. The interactions indicate that vg product plays a role in the differentiation of epidermal and neural cells of the wing disc by interacting with N and h products either directly or indirectly. Mechanisms of molecular interactions among the three loci are discussed.|
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|Language of Publication||English|
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|Title||Journal of Neurogenetics|
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