HomeReference Report
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| Citation | Abu-Issa, R., Cavicchi, S. (1996). Genetic interactions among vestigial, hairy, and Notch suggest a role of vestigial in the differentiation of epidermal and neural cells of the wing and haltere of Drosophila melanogaster. J. Neurogenet. 10(4): 239--246. |
| FlyBase ID | FBrf0090425 |
| Type of publication | Research paper |
| Offprint Available | Yes |
| External Crossreferences | |
| PubMed ID | 8923297 |
| PubMed Abstract | In this paper we describe the results of genetic analysis of the vestigial locus by studying its interactions with hairy and Notch loci in Drosophila melanogaster. Different vestigial alleles in homo- and heterozygous combination with different hairy alleles show synergism in increasing both cell death and formation of ectopic bristles and produce ectopic veins. Interactions between N and vg also show synergism in increasing cell death and formation of ectopic bristles. Only synergism in cell death is seen between h and N. The interactions indicate that vg product plays a role in the differentiation of epidermal and neural cells of the wing disc by interacting with N and h products either directly or indirectly. Mechanisms of molecular interactions among the three loci are discussed. |
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| Secondary IDs | |
| Language of publication | English |
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| Abbreviation | J. Neurogenet. |
| Title | Journal of Neurogenetics |
| Authors | |
| Volume range | 1- |
| Year range | 1983- |
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| Place of publication | London |
| Language of publication | English |
| ISBN/ISSN | 0167-7063 |
| CODEN | JLNEDK |
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Data from Reference
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| Aberrations (4)
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| Alleles (11)
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| Genes (3)
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