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| Citation | Abu-Issa, R., Cavicchi, S. (1996). Genetic interactions among vestigial, hairy, and Notch suggest a role of vestigial in the differentiation of epidermal and neural cells of the wing and haltere of Drosophila melanogaster. J. Neurogenet. 10(4): 239--246. (Export to RIS) | ||
| FlyBase ID | FBrf0090425 | ||
| Publication Type | Research paper | ||
| PubMed ID | 8923297 | ||
| PubMed Abstract | In this paper we describe the results of genetic analysis of the vestigial locus by studying its interactions with hairy and Notch loci in Drosophila melanogaster. Different vestigial alleles in homo- and heterozygous combination with different hairy alleles show synergism in increasing both cell death and formation of ectopic bristles and produce ectopic veins. Interactions between N and vg also show synergism in increasing cell death and formation of ectopic bristles. Only synergism in cell death is seen between h and N. The interactions indicate that vg product plays a role in the differentiation of epidermal and neural cells of the wing disc by interacting with N and h products either directly or indirectly. Mechanisms of molecular interactions among the three loci are discussed. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | J. Neurogenet. | ||
| Title | Journal of Neurogenetics | ||
| Publication Year | 1983- | ||
| ISBN/ISSN | 0167-7063 | ||
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Data from Reference
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| Aberrations (4)
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| Alleles (11)
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| Genes (3)
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