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Reference Report
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| Citation | Bashaw, G.J., Baker, B.S. (1996). Dosage compensation and chromatin structure in Drosophila. Curr. Opin. Genet. Dev. 6(4): 496--501. (Export to RIS) | ||
| FlyBase ID | FBrf0090445 | ||
| Publication Type | Review | ||
| PubMed ID | 8791531 | ||
| PubMed Abstract | The past year has brought significant advances in our understanding of the male-specific lethal (msl genes and dosage compensation in Drosophila. The molecular characterization of the msl-2 gene has, to a great extent, solved the question of how msl-mediated dosage compensation is restricted to males. Molecular analyses of the msl genes have substantiated the proposal that the MSL proteins function as a multimeric complex to mediate dosage compensation. The finding that MSL-2 protein has a RING finger and the demonstration that an insulator protein facilitates the dosage compensation of X-linked genes inserted into the autosomes have opened promising avenues to identify the cis-acting dosage-compensation determinants. | ||
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| Language of Publication | English | ||
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Parent Publication
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| Publication Type | Journal | ||
| Abbreviation | Curr. Opin. Genet. Dev. | ||
| Title | Current Opinion in Genetics and Development | ||
| Publication Year | 1991- | ||
| ISBN/ISSN | 0959-437X | ||
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Data from Reference
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| Genes (11)
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