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Desai, C.J., Sun, Q., Zinn, K. (1997). Tyrosine phosphorylation and axon guidance: of mice and flies.  Curr. Opin. Neurobiol. 7(1): 70--74.
FlyBase ID
FBrf0093088
Publication Type
Review
Abstract

Recent genetic evidence suggests that tyrosine kinases and tyrosine phosphatases can control the guidance of specific growth cones. Within a family of related phosphatases or kinases, individual members can have partially redundant functions. Receptor phosphatases can work together at one guidance choice point, but in opposition at another. The specific combination of kinases and phosphatases active in a growth cone may be an important determinant of pathway choice. One mechanism by which these proteins could control guidance decisions is through regulation of adhesion between growth cones and axons.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Neurobiol.
    Title
    Current Opinion in Neurobiology
    Publication Year
    1991-
    ISBN/ISSN
    0959-4388
    Data From Reference
    Genes (3)