Reference Report

Reference
Citation	Davis, T., Ashburner, M., Johnson, G., Gubb, D., Roote, J. (1997). Genetic and phenotypic analysis of the genes of the elbow-no-ocelli region of chromosome 2L of Drosophila melanogaster. Hereditas 126(1): 67--75. (Export to RIS)
FlyBase ID	FBrf0093413
Publication Type	Research paper
PubMed ID	9175495
PubMed Abstract	The elbow locus is found to be two genes elA and elB, each of which has a distinct phenotype when mutant. Mutations of the elA gene have a strong phenotype where the wing is markedly disrupted. Mutations of elB are weak, mainly affecting the alula and the wing bristles. The two genes are dominant enhancers of each other. Homozygous deletion of the complete elbow region results in lethality. Situated between the elbow genes is the pupal gene and a locus which when deleted causes a crippled leg phenotype. This locus may be a control region for elbow. Immediately adjacent on the proximal side of elA is the no-ocelli locus. The phenotypes of noc alleles vary from extreme, where the ocelli and associated bristles are absent, to weak where these structures are disrupted. The various noc phenotypes are associated with genetically distinct gene regions, mutations of which act as enhancers of each other. Alleles of el and noc show partial failure of complementation, heterozygotes having weak el or weak noc phenotypes. Alleles of both these genes interact with the antimorphic noc allele Sco.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Hereditas
Title	Hereditas
Publication Year	1920-
ISBN/ISSN	0018-0661
Data from Reference
Aberrations (47)
	Df(2L)A47 Df(2L)A178 Df(2L)A400 Df(2L)b81a1 Df(2L)b83d29a Df(2L)b84a2 Df(2L)el14 Df(2L)el15 Df(2L)el16 Df(2L)el17 Df(2L)el20 Df(2L)el28 Df(2L)el80i1 Df(2L)el81i1 Df(2L)el82f1 Df(2L)fn2 Df(2L)fn3 Df(2L)fn27 Df(2L)n78l3 Df(2L)TE35B-1 Df(2L)TE35B-6 Df(2L)TE35B-7 Df(2L)TE35B-12 Df(2L)TE35BC-8 In(2L)el18 In(2L)el⁹ In(2L)noc² In(2L)TE35B-13 In(2LR)el⁶ In(2LR)noc⁴ In(2LR)noc⁷ T(2;3)dpp^s19 T(2;3)el24 T(2;3)GT7 T(2;3)GT8 T(2;3)Mpe T(Y;2)a15 T(Y;2)A80 T(Y;2)el⁴ T(Y;2)GT1 T(Y;2)GT2 T(Y;2)R15 Tp(1;2)TE35B Tp(2;2)A446 Ts(Y;2Lt)a15+Ts(YSt;2Rt)A80 Ts(Y;2Lt)el⁴+Ts(YSt;2Rt)R15 Ts(Y;2Lt)GT2+Ts(YSt;2Rt)A80
Alleles (38)
	elA¹ elA⁸ elA¹⁰ elA¹¹ elA¹² elA¹³ elA²¹ elA²² elA²³ elA²⁴ elA²⁵ elA²⁶ elA²⁷ elA²⁹ elB² elB⁴ elB⁵ elB⁶ elB⁷ elB⁸ elB⁹ elB¹⁰ elB¹¹ elB¹² elB¹³ elB²¹ elB²² elB²³ elB²⁵ elB²⁶ elB²⁷ elB²⁹ noc² noc⁴ noc⁷ noc^GT8 noc^TE35B sna^Sco
Genes (10)
	crle elA elB l(2)35Bc l(2)35Bd mol noc pburs Pgant35A sna