Open Close
Reference
Citation
Riechmann, V., Irion, U., Wilson, R., Grosskortenhaus, R., Leptin, M. (1997). Control of cell fates and segmentation in the Drosophila mesoderm.  Development 124(15): 2915--2922.
FlyBase ID
FBrf0096157
Publication Type
Research paper
Abstract

The primordia for heart, fat body, and visceral and somatic muscles arise in specific areas of each segment in the Drosophila mesoderm. We show that the primordium of the somatic muscles, which expresses high levels of twist, a crucial factor of somatic muscle determination, is lost in sloppy-paired mutants. Simultaneously, the primordium of the visceral muscles is expanded. The visceral muscle and fat body primordia require even-skipped for their development and the mesoderm is thought to be unsegmented in even-skipped mutants. However, we find that even-skipped mutants retain the segmental modulation of the expression of twist. Both the domain of even-skipped function and the level of twist expression are regulated by sloppy-paired. sloppy-paired thus controls segmental allocation of mesodermal cells to different fates.

PubMed ID
PubMed Central ID
DOI
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
  • FBrf0098875
Language of Publication
English
Additional Languages of Abstract
Parent Publication
Publication Type
Journal
Abbreviation
Development
Title
Development
Publication Year
1987-
ISBN/ISSN
0950-1991
Data From Reference
Aberrations (3)
Alleles (10)
Balancers (2)
Genes (16)
Insertions (3)
Experimental Tools (2)
Transgenic Constructs (3)