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Reference
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| Citation |
Dickinson, W.J., Thatcher, J.W. (1997). Morphogenesis of denticles and hairs in Drosophila embryos: involvement of actin-associated proteins that also affect adult
structures. Cell Motility Cytoskel. 38(1): 9--21. |
| FlyBase ID |
FBrf0098231 |
| Type of publication |
Research paper |
| Offprint Available |
Yes |
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External Crossreferences
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| PubMed ID |
9295137 |
| PubMed Abstract |
We sought components that function in morphogenetic events downstream from the segmentation pathway in Drosophila embryos,
so we examined mutations that affect development of adult hairs and/or bristles to identify a subset that also affect hairs
and denticles on the cuticle of first instar larvae. Mutations at 4 of 23 loci surveyed cause distinct abnormalities in these
larval structures, and two other loci have more subtle, variable effects. In particular, forked and singed mutants produce
complex, allele-specific phenotypes. These loci encode actin-associated proteins and, consistent with that information, mutations
cause abnormalities in actin bundles that support nascent hairs and denticles in stage 14-16 embryos. We suggest that interactions
between these and other actin-associated proteins are important in generating the diverse shapes of the cuticular specializations
seen in both larvae and adults.
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| Biosis |
99752650 |
| Zoological record |
13501001262 |
Associated Information
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| Comments |
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| Text of personal communication |
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| Associated files |
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Related Publications
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Also Published As
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Other Reference Information
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| Secondary IDs |
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| Language of publication |
English |
| Additional language(s) of abstract |
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| ISBN |
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| Place of publication |
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Published In
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| Abbreviation |
Cell Motility Cytoskel. |
| Title |
Cell Motility and the Cytoskeleton |
| Authors |
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| Volume range |
6- |
| Year range |
1986- |
| Page range |
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| Publisher |
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| Place of publication |
New York |
| Language of publication |
English |
| ISBN/ISSN |
0886-1544 |
| CODEN |
CMCYEO |
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Data from Reference
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| Aberrations (2)
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| Alleles (34)
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| Genes (23)
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