A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Sun, H., Gilbert, D.J., Copeland, N.G., Jenkins, N.A., Nathans, J. (1997). Peropsin, a novel visual pigment-like protein located in the apical microvilli of the retinal pigment epithelium.  Proc. Natl. Acad. Sci. U.S.A. 94(18): 9893--9898. (Export to RIS)
FlyBase ID FBrf0098949
Publication Type Research paper
PubMed ID 9275222
PubMed Abstract A visual pigment-like protein, referred to as peropsin, has been identified by large-scale sequencing of cDNAs derived from human ocular tissues. The corresponding mRNA was found only in the eye, where it is localized to the retinal pigment epithelium (RPE). Peropsin immunoreactivity, visualized by light and electron microscopy, localizes the protein to the apical face of the RPE, and most prominently to the microvilli that surround the photoreceptor outer segments. These observations suggest that peropsin may play a role in RPE physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds.
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Language of Publication English
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Publication Type Journal
Abbreviation Proc. Natl. Acad. Sci. U.S.A.
Title Proceedings of the National Academy of Sciences of the United States of America
Publication Year 1915-
ISBN/ISSN 0027-8424
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