Home
Reference Report
| Reference | |||
|---|---|---|---|
| Citation | Markova, B.A., Mironova, R.S., Grantcharova, M.L., Georgiev, O.G., Semionov, E.P. (1997). Complex alterations of the ribosomal gene spacers in mutant sc8 of Drosophila melanogaster. Chromosoma 106(6): 361--368. (Export to RIS) | ||
| FlyBase ID | FBrf0099856 | ||
| Publication Type | Research paper | ||
| PubMed ID | 9362544 | ||
| PubMed Abstract | Extreme changes in the proportions of the rDNA intergenic spacers (IGSs) have previously been demonstrated by us in the X-chromosomal rDNA array of the Drosophila melanogaster mutant sc8, where nearly all IGSs were found to be reduced in size. We have cloned different structural variants of the Xsc8 ribosomal units and mapped their spacers by restriction endonuclease analysis. Most of the IGSs exhibited complex rearrangements within the subrepeated region at their 5' terminus. The sequence data revealed the presence of an additional 100 bp subrepeat. In addition, extended deletions/substitutions down to the 18S gene were also found. Examination of the Ysc8 IGS polymorphism indicates that some of the X-chromosomal IGS variants are probably the result of X-Y interchanges. The rarity of alternative recombination products implies that the overabundant deleted spacers in sc8 are generated by nonreciprocal recombination. Our results demonstrate nonrandom distribution of deletional breakpoints within the "1900" region in sc8 and show that the deletions do not truncate the internal IGS subregions at either breakpoint but eliminate them as discrete blocks. | ||
| DOI | |||
| Related Publication(s) | |||
Recent Updates
|
|||
| Description |
What does this section display?
This section contains items that were added to this record for each release.
It currently only tracks new links between this FlyBase report and other
FlyBase data classes (e.g. genes, references, stocks) or controlled
vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
|
||
| Update Feed |
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your
feed reader.
|
||
| FB2013_03 | |||
| FB2013_02 | |||
| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
|
Associated Information
|
|||
| Comments | |||
| Associated Files | |||
|
Other Information
|
|||
| Secondary IDs | |||
| Language of Publication | English | ||
| Additional Languages of Abstract | |||
| Also Published As | |||
|
Parent Publication
|
|||
| Publication Type | Journal | ||
| Abbreviation | Chromosoma | ||
| Title | Chromosoma | ||
| Publication Year | 1939- | ||
| ISBN/ISSN | 0009-5915 | ||
|
Data from Reference
|
|||
| Aberrations (1)
|
|||
| Genes (2)
|
|||