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Citation
Van Vactor, D. (1998). Adhesion and signaling in axonal fasciculation.  Curr. Opin. Neurobiol. 8(1): 80--86.
FlyBase ID
FBrf0102119
Publication Type
Review
Abstract

Numerous in vitro assays and in vivo perturbation studies have led to a model of neural development in which selective fasciculation helps to define accurate axonal projections. Genetic analysis in vivo confirms the hypothesis that axonal fasciculation and defasciculation are controlled by adhesion mechanisms, but also suggests that, in many cases, adhesion and guidance are separable phenomena. In addition, receptors that control the level of tyrosine phosphorylation may play an important role in fasciculation, suggesting that complex intracellular pathways lie just beneath the surface.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Neurobiol.
    Title
    Current Opinion in Neurobiology
    Publication Year
    1991-
    ISBN/ISSN
    0959-4388
    Data From Reference
    Genes (8)