Reference Report

Reference
Citation	Fu, W., Duan, H., Frei, E., Noll, M. (1998). shaven and sparkling are mutations in separate enhancers of the Drosophila pax2 homolog. Development 125(15): 2943--2950. (Export to RIS)
FlyBase ID	FBrf0103260
Publication Type	Research paper
PubMed ID	9655816
PubMed Abstract	We have previously shown that the sparkling gene, which like mammalian Pax2 plays an important role in eye development, is encoded by the Drosophila homolog of Pax2. Here we demonstrate that D-Pax2 also encodes the shaven function, which is crucial during bristle development. Both sv and spa alleles, previously thought to represent different genes, are mutations in two widely separated enhancers of D-Pax2. The sv function of D-Pax2 acts in at least two distinct steps of mechanosensory bristle development: the specification of the alternative fate of shaft as opposed to socket cell, and later the differentiation of the shaft cell.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Development
Title	Development
Publication Year	1987-
ISBN/ISSN	0950-1991
Data from Reference
Aberrations (5)
	Df(4)spa²⁰ Df(4)spa³⁰ Df(4)spa⁴⁷ Df(4)spa⁶⁶ T(3;4)Ubx^A
Alleles (11)
	sv^2.0.cFa sv^6.7.cFa sv^35a sv^+mFa sv^de sv^hs.PF svⁿ sv^spa-1 sv^spa-20 sv^spa-A sv^spa-pol
Constructs (4)
	P{2.0-spa} P{6.7-spa} P{hs-sv.F} P{spa^+mFa}
Genes (4)
	l(4)102EFd l(4)102EFf pho sv
Insertions (4)
	flea{}sv^35a flea{}svⁿ opus{}sv^spa-1 Tirant{}sv^de