Reference Report

Reference
Citation	Diez del Corral, R., Aroca, P., Gomez-Skarmeta, J.L., Cavodeassi, F., Modolell, J. (1999). The Iroquois homeodomain proteins are required to specify body wall identity in Drosophila. Genes Dev. 13(13): 1754--1761. (Export to RIS)
FlyBase ID	FBrf0108698
Publication Type	Research paper
PubMed ID	10398687
PubMed Abstract	The Iroquois complex (Iro-C) homeodomain proteins allow cells at the proximal part of the Drosophila imaginal wing disc to form mesothoracic body wall (notum). Cells lacking these proteins form wing hinge structures instead (tegula and axillary sclerites). Moreover, the mutant cells impose on neighboring wild-type cells more distal developmental fates, like lateral notum or wing hinge. These findings support a tergal phylogenetic origin for the most proximal part of the wing and provide evidence for a novel pattern organizing center at the border between the apposed notum (Iro-C-expressing) and hinge (Iro-C-nonexpressing) cells. This border is not a cell lineage restriction boundary.
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Language of Publication	English
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Parent Publication
Publication Type	Journal
Abbreviation	Genes Dev.
Title	Genes & Development
Publication Year	1987-
ISBN/ISSN	0890-9369
Data from Reference
Aberrations (2)
	Df(3L)iro-DFM1 Df(3L)iro-DFM3
Alleles (7)
	ara^Scer\UAS.cGa caup^{Scer\UAS.cdCa} Ecol\lacZ^arm.PV Ecol\lacZ^Egfr-09261 mirr^DFM3 mirr^e48 Scer\GAL4^ap-md544
Constructs (3)
	P{arm-lacZ.V} P{UAS-ara.G} P{UAS-caup.dC}
Genes (12)
	anon-69Da anon-69Db ara bi caup Ecol\lacZ mirr nub Scer\GAL4 tsh vg wg
Insertions (2)
	P{GawB}ap^md544 P{PZ}Egfr⁰⁹²⁶¹