|Citation||Ramirez-Weber, F.A., Kornberg, T.B. (1999). Cytonemes: cellular processes that project to the principal signaling center in Drosophila imaginal discs. Cell 97(5): 599--607. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||Wing imaginal disc cells in Drosophila develop by using information received from a signaling center associated with the anterior/posterior compartment border. We show here that disc cells have thin, actin-based extensions (cytonemes) that project to this signaling center. Cytonemes can be induced when cells from the lateral flanks of a wing disc are cultured next to cells from the A/P border or next to a source of fibroblast growth factor. Mouse limb bud cells also grow projections during a brief culture period, indicating that cytonemes are an attribute of both vertebrate and invertebrate cells. We suggest that cytonemes may be responsible for some forms of long-range cell-cell communication.|
|Review||The long arms of the cell.
Bray, 1999, Trends Genet. 15(9): 352 [FBrf0125303]
Jones, 1999, Curr. Opin. Genet. Dev. 9(4): 381 [FBrf0125320]
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|Language of Publication||English|
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