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| Citation | Qureshi, S.T., Gros, P., Malo, D. (1999). Host resistance to infection: genetic control of lipopolysaccharide responsiveness by TOLL-like receptor genes. Trends Genet. 15(8): 291--294. (Export to RIS) | ||
| FlyBase ID | FBrf0110608 | ||
| Publication Type | Review | ||
| PubMed ID | 10431187 | ||
| PubMed Abstract | Gram-negative bacterial lipopolysaccharide evokes a protective inflammatory response in the normal host. Through genetic analysis of mutant mice, the gene encoding Toll-like receptor 4 (Tlr4) was recently identified as a critical component of this host defense mechanism. Tlr4 is a member of an ancient gene family that regulates antimicrobial host defense in plants, invertebrates and mammals. | ||
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| FB2013_03 | |||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Trends Genet. | ||
| Title | Trends in Genetics | ||
| Publication Year | 1985- | ||
| ISBN/ISSN | 0168-9525 | ||
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Data from Reference
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| Genes (11)
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