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Reference Report
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| Citation | Blake, K.J., Myette, G., Jack, J. (1999). ribbon, raw, and zipper have distinct functions in reshaping the Drosophila cytoskeleton. Dev. Genes Evol. 209(9): 555--559. (Export to RIS) | ||
| FlyBase ID | FBrf0111332 | ||
| Publication Type | Research paper | ||
| PubMed ID | 10502112 | ||
| PubMed Abstract | rib and raw mutations prevent cells in a number of tissues from assuming specialized shapes, resulting in abnormal tubular epithelia and failure of morphogenetic movements such as dorsal closure. Mutations of zip, which encodes the nonmuscle myosin heavy chain, suppress the phenotypes of rib and raw, suggesting that rib and raw are not directly required for myosin function. Abnormal formation of the actin cytoskeletal structures underlying embryonic cuticular hairs suggests possible roles for rib and raw in organizing the actin cytoskeleton. The actin prehair structures are absent in rib mutants and abnormally shaped in raw mutants, indicating that the two genes have different functions required for organizing the actin cytoskeleton. | ||
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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Parent Publication
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| Publication Type | Journal | ||
| Abbreviation | Dev. Genes Evol. | ||
| Title | Development genes and evolution | ||
| Publication Year | 1996- | ||
| ISBN/ISSN | 0949-944X | ||
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Data from Reference
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| Alleles (7)
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| Genes (4)
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