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Reference Report
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| Citation | Dorsett, D. (1999). Distant liaisons: long-range enhancer-promoter interactions in Drosophila. Curr. Opin. Genet. Dev. 9(5): 505--514. (Export to RIS) | ||
| FlyBase ID | FBrf0111358 | ||
| Publication Type | Review | ||
| PubMed ID | 10508687 | ||
| PubMed Abstract | Transcriptional activation of many developmentally regulated genes is mediated by proteins binding to enhancer sequences located several kilobases from the promoter. Existing models for how activator proteins function do not adequately explain long-range activation. Recent experiments in Drosophila on insulators that block enhancer-promoter interactions, interchromosomal activation, and mutants deficient in long-range activation are consistent with models in which facilitator factors that function between enhancers and promoters bring them into physical proximity of each other. | ||
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| FB2013_03 | |||
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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Other Information
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| Language of Publication | English | ||
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Parent Publication
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| Publication Type | Journal | ||
| Abbreviation | Curr. Opin. Genet. Dev. | ||
| Title | Current Opinion in Genetics and Development | ||
| Publication Year | 1991- | ||
| ISBN/ISSN | 0959-437X | ||
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Data from Reference
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| Alleles (3)
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| Genes (16)
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| Natural transposons (2)
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