Dear Chihiro,
the gene we call reggie-2 is identical to the already published gene
flotillin-1 (Galbiati et al., Gene  210:229-237  (1998)). We decided to
stick to the name reggie-2 since the homologous sequence (from Carassius
auratus) was first published as reggie-2 (Schulte et al., Development
 124:577-587  (1997)) and this name indicates the gene's function during
neural regeneration (at least in the fish).
Galbiati et al. also mention a gene they call flotillin-2 which might be
identical to reggie-1, but we believe that reggie-1 codes for a protein
49aa longer (N-terminally) than the published flotillin-2. Our
chromosomal-in-situ-hybridizations suggest that reggie-1 is located on the
X-chromosom (region 13).
Sincerely yours,
Martin
On Tue, 14 Sep 1999, Chihiro Yamada wrote:
> Subject: EDRC99 - abstract ID253
>
> Dear Dr. Hoehne,
>
> We are currently curating the abstracts for the upcoming European
> Drosophila Research Conference in Zurich, for FlyBase. I am writing in
> connection with your abstract:
>
> 'Characterization of Drosophila homologues of reggie, a gene family
> associated with neural regeneration in vertebrates'
>
> You mention 2 genes that are new to FlyBase, reggie-1 and reggie-2.
>
> Do you have a map location for reggie-1 and reggie-2? It is nice if we
> can keep as many gene records as possible anchored to the map.
>
> Also, do you have symbols for these genes ? Reg-2 is already in use
> (for 'Rhythmically expressed gene 2' and Reg-1 (for 'Rhythmically
> expressed gene 1') is a synonym for Adh, however, rgg-1 and rgg-2 are
> not in use.
>
> Thank you for your help,
>
> with best wishes,
>
> Chihiro