Open Close
Reference
Citation
Nunez, G., del Peso, L. (1998). Linking extracellular survival signals and the apoptotic machinery.  Curr. Opin. Neurobiol. 8(5): 613--618.
FlyBase ID
FBrf0111693
Publication Type
Review
Abstract

The survival of cells in multicellular organisms requires continuous stimulation from the extracellular environment. The phosphatidylinositol-3' kinase/Akt signaling cascade has been identified as a critical pathway for the transduction of extracellular survival signals. The finding that the pro-apoptotic protein BAD is a substrate of Akt/PKB has provided the first link between extracellular survival signals and the apoptotic machinery.

PubMed ID
PubMed Central ID
DOI
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Neurobiol.
    Title
    Current Opinion in Neurobiology
    Publication Year
    1991-
    ISBN/ISSN
    0959-4388
    Data From Reference
    Genes (3)