Reference Report

Reference
Citation	Ashburner, M., Roote, J., Lewis, S.E., Rubin, G.M. (1999.10.12). Adh.
FlyBase ID	FBrf0112153
Type of publication	Personal communication to FlyBase
Offprint Available	No
External Crossreferences
PubMed ID
PubMed Abstract
Biosis
Zoological record
Associated Information
Comments
Text of personal communication	From ma11@XXXXXXXXXXXXXXX Tue Oct 12 09:51:40 1999 Envelope-to: gm119@XXXXXXXXXXXXXXX Delivery-date: Tue, 12 Oct 1999 09:51:40 +0100 To: gm119@XXXXXXXXXXXXXXX Subject: Adh Cc: ma11@XXXXXXXXXXXXXXX X-Sun-Charset: US-ASCII From: Michael Ashburner (Genetics) <ma11@XXXXXXXXXXXXXXX> Date: Tue, 12 Oct 1999 09:53:33 +0100 Content-Length: 190201 Gillian This is our working file. It can be taken as a personal communication to FlyBase from Ashburner, Misra, Roote, Lewis & Rubin. This version will have the new genes analysed since the paper was submitted. These should be curated. This file is authorative over the paper [except for the 'product' lines which were never u/dated]. Also ignore the 'cytology' & lines & refs - these were all unaltered from FB about a year ago. Ignore the .* suffixes on EST names. MA ========================================================================== Region 34-36 genes. Michael Ashburner and John Roote and Sima Misra and Suzanna Lewis and Gerry M. Rubin. Version 18.1 13 Sept. 1999 \+symbol = identified on sequence direction = direction of transcription + = distal to proximal - = proximal to distal ? = unclear since only P insertion product - often very very tentative BLAST results: expect < e-7 GB = GenBank/dbEST TBLASTX SP = SwissProt BLASTX TR = trEMBL BLASTX YPD = yeast protein database BLASTX genefinder scores > 20 genscan scores > 45 If only part of gene prediction used, indicated number of spans. \* = split gene prediction between 2 gene records. Results in parentheses less than the above cutoffs. =========================================================================== \+symbol: B4 \+formal_name: BG:DS07660.4 references: Sotillos et al., 1997 Development 124: 4769-4779 cDNA_sequence: AF022364; g2636727 pr_sequence_TREMBL:O16865 P_element_allele: PZ05337 sequenced EP2503 sequenced genefinder: 48(BACR48E02)/21(BACR48E02) genscan: 153(BACR48E02) product: match_to: SP P46591 e-9 O (Candida albicans) match_to: SP P08399 e-7 M (serine residues) EST: LD07105.5', LD33628.5' BAC: BACR48E02 direction: - MA_notes: This is a divergent transcript from kuz encoding a 964 aa protein with no matches. 5' ends of anon-B4 and kuz a few kb apart Sotillos et al., 1997. SM_notes: Translation from alignment to GenBank AF022364 (only 1-2314 of 4053). n(2)05337 maps to 187441 (in 4th exon), EP2503 maps to 151575 of BACR48E02 (in 1st exon). =========================================================================== \+symbol: BG:BACR48E02.1 \+formal_name: BG:BACR48E02.1 genefinder: 21 genscan: (31) product: match_to: EST: BAC: BACR48E02 direction: - Nested_in: B4 SM_notes: Translation from Genefinder. =========================================================================== \+symbol: BG:BACR48E02.2 \+formal_name: BG:BACR48E02.2 genefinder: (15) genscan: 63 product: match_to: EST: BAC: BACR48E02 direction: + Nested_in: B4 SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:BACR48E02.3 \+formal_name: BG:BACR48E02.3 genefinder: 23 genscan: 54 product: match_to: EST: BAC: BACR48E02 direction: + Nested_in: B4 SM_notes: Translation from Genscan. =========================================================================== \+symbol: kuz \+formal_name: BG:DS07660.3 synonym: l(2)34Da synonym: l(2)03782 name: kuzbanian UID: FBgn0015954 references: FBrf0089802 == Rooke et al., 1996, Science 273(5279): 1227--1231 FBrf0090545 == Fambrough et al., 1996, Proc. Natl. Acad. Sci. USA. 93(23): 1 3233--13238 Sotillos et al., 1997 Development 124: 4769-4779 cytology: 34C5--34C5 cytology_data: Left limit from inclusion within Df(2L)b88c75 (FBrf0092813) cytology_data: Right limit from in situ hybridisation (FBrf0067338) cDNA_sequence:U60591; g1531633 pr_sequence_TREMBL:Q94902 genefinder: 23/77(BACR48E02) genscan: 286/83(2 spans)(BACR48E02) product: metalloprotease/disintegrin family protein match_to: TR G2739037 (AF024614) e-128 W match_to: TR E1246683 (Z96047) e-128 W match_to: TR O14672 (AF009615) e-113 H match_to: TR O35598 (AF011379) e-112 M EST: LD04086.5', LD20268.5', LD04356.5' BAC: BACR48E02 direction: + TE_insert_allele: kuz¹ (TE13=TE34Cb) kuz² (TE60=TE34Ca) kuz³ (TE94=TE34Cc) P_element_allele: kuz^k01403 sequenced l(2)k01405, cluster mate ? kuz^k07601 sequenced kuz^k12004 sequenced kuz^k14817 sequenced kuz^k09934 kuz^k11804 kuz^k14701 l(2)03782⁰³⁷⁸² (hypomorphic allele) sequenced rK028 sequenced P_element_derivative_allele: kuz^e29-4 kuz^k01405Rev4 kuz^k01405Rev11 kuz^k01405Rev23 aberration_associated_allele: kuz^TE34Cc-GV2 (In(2)TE34Cc-2) kuz^TE34Cc-SV1 (In(2L)TE34Cc-1) kuz^TE34Cc-GV1 (T(2;3)TE34Cc-1) kuz^TE34Ca-GV1 (T(Y;2)TE34Ca-1) misc_allele: kuz^IK5 kuz^H143 phenotypic_class: vital. SM_notes: Translation from alignment to GenBank U60591 (edited 3' end of 2nd exon). rK028 maps to 151448 of BACR48E02. =========================================================================== \+symbol: BG:DS07660.1 \+formal_name: BG:DS07660.1 genefinder: 20(BACR48E02) genscan: 99(BACR48E02) product: Na-dependent transporter match_to: TR Q94886 (Y07720) e-56 D match_to: SP Q03567 e-72 W match_to: TR Q62634 (U07609) e-60 M match_to: SP Q61983 e-55 M match_to: SP Q14916 e-44 H match_to: TR G3582333 (AC005496) e-57 A match_to: LP07553.5' e-42 D EST: BAC: BACR48E02 direction: - Nested_in: kuz SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:BACR48E02.4 \+formal_name: BG:BACR48E02.4 genefinder: 42 genscan: 68 product: ras suppressor protein rsp-1 match_to: SP Q15404 e-69 H match_to: SP Q01730 e-68 M match_to: TR Q09497 (Z46996) e-58 W match_to: TR E1226129 (Y16045) e-15 A EST: LD13077.5', LD11984.5', LD18845.5', LP02171.5' BAC: BACR48E02 direction: - SM_notes: Translation from full-length LD13077. =========================================================================== \+symbol: BG:DS01368.1 \+formal_name: BG:DS01368.1 genefinder: 80(DS01368) genscan: 153(DS01368) product: match_to: TR Q18202 e-13 W EST: CK00026.3', LP04233.5' P1: DS01368 direction: + SM_notes: Translation from full-length CK00026. CK00026.3' matches but CK00026.5prime.contig sequence does not match; only nts 612-2123 of 2131 CK00026 full-length sequence align by sim4. LP04233.5' looks alternatively spliced, overlaps exon 4 and 6, not 5. =========================================================================== \+symbol: BG:DS08249.1 \+formal_name: BG:DS08249.1 genefinder: 36 genscan: 139(DS01368)/103(DS08249) product: similar to lachesin? match_to: SP Q26474 e-9 O (grasshopper) EST: P1: DS01368, DS08249, BACR48E02 direction: - SM_notes: Translation from Genscan on DS01368. match_to: GB Z81045;g1627647 e-8 W but by 1/99 this protein in the cosmid accession no longer exists. =========================================================================== \+symbol: BG:DS08249.2 \+formal_name: BG:DS08249.2 genefinder: 73 genscan: 163 product: mitochondrial glycerol 3-phosphate dehydrogenase match_to: GB U12424 e-87 H match_to: SP P43304 e-97 H match_to: GB U60987 e-87 M match_to: SP Q64521 e-100 M match_to: TR E1323155 e-97 W (EMBL; Z72516) match_to: GB Z73906 e-67 W match_to: TR P90795 e-78 W match_to: YPD 763191 e-61 Y match_to: SP P32191 e-52 Y EST: P1: DS08249 direction: + SM_notes: Genefinder used rather than Genscan for translation since Genscan adds on stuff at amino terminus. =========================================================================== \+symbol: BG:DS08249.3 \+formal_name: BG:DS08249.3 genefinder: 50 genscan: 91 product: match_to: TR G3342562 e-72 H (EMBL; AF077599) match_to: GB AA305709 e-29 H (Hum EST) match_to: GB AA212211 e-13 M (Mus EST) match_to: LD19320.5' e-16; LD28635.5' e-16 EST: P1: DS08249 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS08249.4 \+formal_name: BG:DS08249.4 genefinder: 38 genscan: 97 product: match_to: EST: P1: DS08249 direction: + SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS08249.5 \+formal_name: BG:DS08249.5 genefinder: (18) genscan: 50 product: match_to: EST: P1: DS08249 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS00797.1 \+formal_name: BG:DS00797.1 synonym: l(2)k07245 UID: FBgn0022093 genefinder: 59 genscan: 185 product: similar to Yeast EMP70 (70kd endomembrane) gene product P24A protein precursor match_to: GB D87444 e-159 H (KIAA0255) match_to: TR Q92544 e-210 H (KIAA0255) match_to: TR Q94422 e-180 W match_to: TR E1247604 e-180 W match_to: TR Q12101 e-103 Y match_to: SP P32802 e-102 Y match_to: GB X67316 e-50 Y match_to: GB AA272456 e-37 M (Mus EST) match_to: GB AA117787 e-35 M (Mus EST) match_to: TR O04091 e-73 A match_to: GB T45159 e-24 A EST: HL07777.5'; HL07777.3'; LD32761.5'; GH02822.5' P_element_allele: l(2)k07245 sequenced P1: DS08284 direction: + SM_notes: k07245 inserted at 7502 of DS08284, LD32671.5' is from 7511-8360, extends further 5' than HL07777. Translation from full-length LD32761 sequence. =========================================================================== \+symbol: BG:DS00797.2 \+formal_name: BG:DS00797.2 genefinder: 39 genscan: 77 product: match_to: YPD 854436 e-16 Y match_to: GB C90076 e-15 O (Dictyostelium discoideum) EST: HL03175.5'; HL03175.3' P1: DS08284 direction: - SM_notes: Translation from full-length HL03175 sequence. =========================================================================== \+symbol: p38b \+formal_name: BG:DS00797.3 genefinder: 71 genscan: 173 product: MAP Kinase match_to: GB L35253 e-115 H match_to: GB L35264 e-115 H match_to: SP Q16539 e-136 H match_to: GB U10871 e-116 M match_to: SP P47811 e-136 M match_to: TR Q17466 e-116 W match_to: SP P32485 e-92 Y match_to: SP Q39026 e-86 A EST: GM01004.3'; GM01004.5'; GM04790.5'; GM06395.5'; HL03933.5'; LD24658.5' P1: DS08284 direction: + SM_notes: Translation from full-length GM01004. =========================================================================== \+symbol: BG:DS00797.4 \+formal_name: BG:DS00797.4 genefinder: 30 genscan: 69 product: match_to: TR Q17843 e-31 W match_to: GB Z81275 e-24 O (Scrofa EST) match_to: GB AA114025 e-19 H (Hum EST) match_to: GB R90322 e-16 A (Arabidopsis EST) EST: P1: DS08284 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS00797.5 \+formal_name: BG:DS00797.5 genefinder: 87 genscan: 296 product: ABC transporter match_to: GB X97187 e-82 H match_to: TR Q92473 e-102 H match_to: TR Q99758 e-102 H match_to: GB AF000149 e-71 M match_to: SP P41233 e-86 M match_to: TR O01790 e-69 W match_to: TR O22231 e-58 A match_to: SP P55476 e-31 B EST: CK01017.3'; CK01017.5'; LD33192.5' P1: DS08284 direction: + SM_notes: Translation from complete sequence of CK01017 at 5' end and LD33192 at 3' end--neither full-length. Because homology extends 5' of CK01017 and this library not full-length clones, gene may extend further 5' than translation. =========================================================================== \+symbol: BG:DS00797.6 \+formal_name: BG:DS00797.6 genefinder: 71 genscan: 170 product: match_to: TR Q25239 e-10 O (Lucilia cuprina) EST: P1: DS08284 direction: + SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS00797.7 \+formal_name: BG:DS00797.7 genefinder: 218 genscan: 632 product: guanine nucleotide-exchange protein (SEC7) match_to: GB J03918 e-161 Y match_to: SP P11075 e-178 Y match_to: TR G2674107 0.0 O (Bos taurus) match_to: TR E1287857 e-181 A match_to: TR Q92538 e-51 H match_to: GB M85169 e-42 H match_to: TR O08967 e-44 M match_to: SP P34512 e-25 W EST: LD10472.3'; LD10472.5'; HL01681.5'; LD29171.5' P1: DS08284 direction: + MA_note: Bet this is anon-34Da SM_notes: Translation from full-length LD29171. =========================================================================== \+symbol: BG:DS00941.1 \+formal_name: BG:DS00941.1 genefinder: 56 genscan: 122 product: carbonic anhydrase match_to: GB U55177 e-50 O (Danio rerio) match_to: TR G2576335 e-53 O (Danio rerio) match_to: SP P23589 e-47 M match_to: GB X51971 e-40 M match_to: SP P43166 e-50 H match_to: GB L19297 e-40 H match_to: TR Q21614 e-28 W match_to: GB Z68118 e-14 W match_to: TR O04846 e-7 A EST: GH09688.5'; GH05601.3'; GH06111.3'; GH08627.5'; GH08470.5'; GH05849.5' P1: DS00941 direction: + SM_notes: Translation from full-length GH09688, but problem aligning 1321-2642 (internal exon) of GH09688; GH05601.3' and GH05601.3' align there so used these for middle of 3rd exon. =========================================================================== \+symbol: BG:DS00941.2 \+formal_name: BG:DS00941.2 genefinder: 55 genscan: 54 product: RNA editase match_to: GB X99383 e-23 H match_to: GB U76420 e-23 H match_to: SP P55265 e-18 H match_to: TR G2981097 e-16 M match_to: SP Q22618 e-15 W match_to: SP P53065 e-12 Y EST: P1: DS00941 direction: - SM_notes: Translation from Genscan. Missing key dsRNA binding domains. MA_notes: Liam Keegan (Edinburgh) named it Adat and think it is a tRNA adenosine deaminase =========================================================================== \+symbol: BG:DS00941.3 \+formal_name: BG:DS00941.3 genefinder: 44 genscan: 99 product: match_to: GB D76471 e-7 M (Mus EST) match_to: TR G2772565 e-12 H (Hum EST) EST: P1: DS00941 direction: + SM_notes: Translation from Genscan. =========================================================================== symbol: l(2)34Db name: lethal (2) 34Db UID: FBgn0001959 references: cytology: 34D3--34D3 cytology_data: Left limit from inclusion within Df(2L)b81a1 (FBrf0091422) cytology_data: Right limit from complementation mapping against In(2L)tsh3 (citation unavailable) ems_allele: l(2)34Db¹ l(2)34Db² l(2)34Db³ l(2)34Db⁴ l(2)34Db⁵ l(2)34Db⁶ l(2)34Db⁷ l(2)34Db⁸ l(2)34Db⁹ l(2)34Db¹⁰ l(2)34Db¹¹ l(2)34Db¹² misc_allele: l(2)34Db^AS1 aberration_associated_allele: l(2)34Db^tsh3 (In(2L)tsh3) phenotypic_notes: escapers with rough eyes; etched wing margin; bristle loss etc; fertile both sexes. phenotypic_class: vital. JR_notes: OM's in situs of DS00797 suggest that this P1 is almost entirely distal to tsh³ break, ie that 34Db is probably either BG:DS00941.1, .2 or .3. One lethal excision (out of loads of viables) from k07245 is kuz^-, 34Db⁺, Sos⁺, black⁺ i.e. 34Db is to the right of k07245. =========================================================================== symbol: anon-34Da synonym: transcript 7 references: FBrf0057637 == Bonfini et al., 1992, Science 255: 603--606 MA_note: Bet this is BG:DS00797.7 =========================================================================== \+symbol: Sos \+formal_name: BG:DS00941.4 name: Son of sevenless synonym: l(2)34Ea UID: FBgn0001965 references: FBrf0057637 == Bonfini et al., 1992, Science 255: 603--606 FBrf0053370 == Rogge et al., 1991, Cell 64: 39--48 FBrf0053392 == Simon et al., 1991, Cell 67: 701--716 FBrf0057544 == Bowtell et al., 1992, Proc. Natl. Acad. Sci. USA. 89: 6511--6515 FBrf0057536 == Rogge et al., 1992, Proc. natn. Acad. Sci. USA. 89: 5271--5275 cytology: 34D4--34D4 cytology_data: Left limit from complementation mapping against In(2LR)b71k1A (FBrf0091347) cytology_data: Right limit from non-inclusion within Df(2L)b77c (citation unavailable) product: guanine-nucleotide-exchange-factor motifs: PS00720 == Guanine-nucleotide dissociation stimulators CDC25 family signature. motifs: PS50003 == PH domain profile. genefinder: 230 genscan: 573 match_to: TR Q07889 e-254 H match_to: TR G303382 e-254 H match_to: TR Q62245 e-249 M match_to: GB L13857 e-232 H match_to: GB Z11574 e-229 M match_to: SP P04821 e-26 Y match_to: TR Q22503 e-14 W EST: GH01796.5' P1: DS00941 direction: + homology: species == Homo sapiens; gene == SOS2; GDB: 230041; OMIM: 601247 MEDLINE: 94102743 homology: species == Homo sapiens; gene == SOS1; GDB: 230004; OMIM: 182530 homology: species == Mus; gene == Sos1; MGD: MRK-14489 homology: species == Mus; gene == Sos2; MGD: MRK-14490 cDNA_sequence:M83931; g158485 genomic_sequence:M77501; g158471 pr_sequence_PIR:A41216 pr_sequence_SwissProt:P26675 ems_allele: Sos^34Ea-1 Sos^34Ea-2 Sos^34Ea-3 Sos^34Ea-4 Sos^34Ea-5 Sos^34Ea-6 Sos^34Ea-7 Sos^34Ea-8 Sos^34Ea-9 Sos^34Ea-10 Sos^34Ea-11 Sos^34Ea-12 Sos^34Ea-13 Sos^34Ea-14 Sos^34Ea-15 Sos^34Ea-16 Sos^34Ea-17 Sos^34Ea-18 Sos^34Ea-19 Sos^F1 Sos^eCN6 Sos^eCS3 Sos^eDN4 Sos^eJ2 Sos^eN6 P_element_allele: E(var)309¹ E(var)189¹ l(2)k05224 sequenced l(2)k06321 l(2)k05705 misc_allele: Sos^JC2 Sos^Sutor-157 Sos^Sutor-405 Sos^e0D Sos^e1A Sos^e2H Sos^e4G Sos^e6C Sos^ex63 Sos^x122 Sos^x15 phenotypic_class: vital. phenotypic_notes: escapers with small rough eyes; wing vein gaps. SM_notes: Translation from alignment of GenBank M83931. =========================================================================== \+symbol: b \+formal_name: BG:DS00941.5 name: black synonym: Gad2 synonym: anon-34Db synonym: transcript 1 Bonfini UID: FBgn0000153 UID: FBgn0005622 references: FBrf0064653 == Phillips et al., 1993, J. Neurochem. Suppl. 61(4): 1291--1301 FBrf0082478 == Phillips et al., 1995, Abstr. Europ. Symp. Dros. Neurobiol. 5: 44--45 FBrf0053317 == Phillips et al., 1991, Greenspan, Palka, 1991: 97 cytology: 34D6--34D6 cytology_data: Left limit from complementation mapping against T(2;3)b^79b6 (citation unavailable) cytology_data: Right limit from complementation mapping against T(2;3)b^79b6 (citation unavailable) enzyme: glutamate decarboxylase == EC 4.1.1.15 cDNA_sequence:U01239; g402252 pr_sequence_TREMBL:Q24062 pr_sequence_PIR:JH0827 genefinder: 109 genscan: 259 match_to: GB X69936 e-109 H match_to: SP Q05329 e-115 H match_to: TR Q64611 e-127 O (Rattus norvegicus) match_to: TR O35119 e-114 M match_to: SP P48320 e-114 M match_to: GB L16980 e-110 M match_to: GB Z14925 e-14 W EST: HL08051.5'; HL07852.5' P1: DS00941 direction: + spontaneous_allele: b¹ b^14b28 b^18c27 b^23b2 b^24b15 b²⁹ b^34g b³⁹ b^39j b^40c b^82c1 UV_allele: b^50d b^51f gamma_ray_allele: b⁶⁶¹ b^71k2 b^75a b^76e1 b^76e2 b^76f3 b^77j b^78a b^79b1 b^79d2 b^79df2 b^79dt3 b^79g2 b^79h2 b^79h3 b^80c1 b⁸⁰ⁱ² b⁸⁰ⁱ³ b^80j1 b^80j2 b^80k1 b^80k2 b^80l1 b^80l2 b^81a2 b^81c17 b^81c2 b^81f2 b^81h2 b^81k b^81l2 b^81l40 b^81l42 b^83b1 b^83b40 b^83c20 b^83c25 b^83c26 b^83c35a b^83c35b b^83c36 b^83c47 b^83f17 b^83f18 b^83f51 b^83f52 b^84b1 b^84h70 b^85b3 b^85b4 caffeine/gamma_ray_allele: b^74b2 b^74b4 b^74b5 b^74c2 b^74c4 b^74c5 b^74d2 b^74d4 b^74d6 b^76b1 b^76b2 actinomycin_D/gamma_ray_allele: b^76j1 b^76j2 b^76j3 b^76k1 b^76k2 b^77a1 b^77a2 b^77a3 b^77a4 b^77a5 NaF/gamma_ray_allele: b^78f1 b^78f2 b^78g b^78k1 b^78k2 b^78k3 b^78k4 b^78k5 neutrons/gamma_ray_allele: b^79d6 b^79d8 b^79dt0 X_ray_allele: b^77.1X b^77.2X b^77.5X b^83fXD b^84g b^84h34 b^84h40 neutron_allele: b^79a1 b^79a2 b^79a3 b^79b7 b^79d4 b^79dt1 b^81c b^82c16 b^82c3 b^82c54 b^82c7 b^83d29b b^83d35 b^83d36 b^83l b^85c3 ems_allele: b^75f b^77.3e b^77.4e b^A b^A51 b^A53 b^A54 b^A55 diepoxyoctane_allele: b^78.1 misc_allele: b^66h b^81dt P_element_allele: b^P aberration_associated_allele: b^36f (Tp(2;3)dp) b^79b6 (T(2;3)b^79b6) b^79d5 (In(2L)b^79d5) b^79d6 (T(2;3)b^79d6) b^79h1 (Tp(2;2)b^79h1) b^80c2 (In(2L)b^80c2) b^81a (In(2LR)b81a2) b^81f1 (Df(2L)b81f1) b^81f3 (In(2L)b^81f3) b^81l17 (In(2L)b^81l7) b^82c44 (In(2L)b^82c44) b^83b2 (In(2L)b^83b22) b^85c2 (T(2;3)b^85c2) phenotypic_notes: black body color; puparial case light; lacks beta-alanine; presumably on beta-alanine pathway. phenotypic_class: visible; non_vital. misc_note: if GAD acts as an aspartate decarboxylase then b = Gad2. JR_notes: Marie Phillips (Melbourne) wrote (1991) that Gad2 was in Df(2L)b84a4 but not in Df(2L)b84a8. SM_notes: Translation from alignment of GenBank U01239. =========================================================================== \+symbol: tamas \+formal_name: BG:DS00941.6 name: lethal (2) 34Dc synonym: DNApol-γ125 synonym: l(2)34Dc synonym: anon-34Dc synonym: transcript 2 Bonfini UID: FBgn0001960 UID: FBgn0004406 references: FBrf0090361 == Lewis et al., 1996, J. Biol. Chem. 271(38): 23389--23394 FBrf0092749 == Ropp and Copeland, 1996, Genomics 36(3): 449--458 FBrf0089488 == Ropp, 1996.9.23, personal communication FBrf0056420 == Olson and Kaguni, 1992, J. Biol. Chem. 267: 23136--23142 FBrf0050857 == Kaguni and Olson, 1989, Proc. natn. Acad. Sci. USA. 86(17): 6469--6473 FBrf0047578 == Wernette et al., 1988, Biochemistry 27: 6046--6054 FBrf0044677 == Wernette and Kaguni, 1986, J. Biol. Chem. 261(31): 14764--14770 FBrf0063558 == Kaguni et al., 1988, Cancer Cells 6: 425--432 FBrf0064748 == Williams et al., 1993, J. Biol. Chem. 268(33): 24855--24862 FBrf0079622 == Williams and Kaguni, 1995, J. Biol. Chem. 270(2): 860--865 FBrf0085690 == Olson et al., 1995, J. Biol. Chem. 270(48): 28932--28937 FBrf0090538 == Dusenbery and Smith, 1996, Mutat. Res. 364(3): 133--145 cytology: 34D6--34D8 cytology_data: Left limit from complementation mapping against In(2L)b^79d5 (citation unavailable) cytology_data: Right limit from inclusion within Df(2L)b82a3 (citation unavailable) enzyme: mitochondrial DNA-directed DNA polymerase, catalytic subunit == EC 2.7.7.7 genefinder: 143 genscan: 337 match_to: TR Q92515 e-232 H match_to: GB U60325 e-215 H match_to: GB X98093 e-215 H match_to: SP P54099 e-216 M match_to: GB U53584 e-203 M match_to: SP P15801 e-129 Y match_to: GB Z75238 e-104 Y match_to: GB D35928 e-10 W EST: LD06421.5'; LD18609.5'; LD02053.5' P1: DS00941 direction: - genomic_sequence:U60298; g1401344 cDNA_sequence:U62547; g1552493 pr_sequence_SwissProt:Q27607 pr_sequence_TREMBL:Q94906 ems_allele: l(2)34Dc¹ l(2)34Dc² l(2)34Dc³ l(2)34Dc⁴ l(2)34Dc⁵ l(2)34Dc⁶ l(2)34Dc⁷ l(2)34Dc⁸ phenotypic_class: vital. JR_notes: Ann Regina Campos (Ontario) picked up as mutation in adult/larval visual system; B. Iyengar <iyengabg@XXXXXXXXXXXXXXX> SM_notes: Translation from alignment of GenBank U62547. =========================================================================== \+symbol: Sop2 \+formal_name: BG:DS00941.7 name: Suppressor of profilin synonym: l(2)34Dd UID: FBgn0001961 references: <camposa@XXXXXXXXXXXXXXX> to JR 13 March 1997. cytology: 34D6--34D8 cytology_data: Left limit from complementation mapping against In(2L)b79h1A (citation unavailable) cytology_data: Right limit from inclusion within Df(2L)b82a3 (citation unavailable) homology: species == S. pombe; gene == sop2 EMBO J. 15: 6426 genefinder: 75 genscan: 199 match_to: TR Q92747 e-106 H match_to: GB Y08999 e-102 H match_to: GB Z36103 e-59 Y match_to: SP P38328 e-60 Y match_to: GB W08597 e-49 M (Mus EST) match_to: GB AA408535 e-49 M (Mus EST) match_to: GB C12211 e-36 W EST: CK00388.3' P1: DS00941 direction: - ems_allele: l(2)34Dd¹ l(2)34Dd² l(2)34Dd³ phenotypic_notes: interallelic escapers. phenotypic_class: vital. JR_notes: Information on product & orders from Andrew Hudson (chez Cooley). SM_notes: Translation from alignment of cDNA from A. Hudson (from GM library). =========================================================================== \+symbol: Orc5 \+formal_name: BG:DS00941.8 name: Origin recognition complex subunit 5 synonym: l(2)34Df UID: FBgn0001963 references: FBrf0085120 == Gossen et al., 1995, Science 270(5242): 1674--1677 FBrf0086393 == Ehrenhofer-Murray et al., 1995, Science 270(5242): 1671--1674 cytology: 34D6--34E2 cytology_data: Left limit from non-inclusion within Df(2L)b88b42 (citation unavailable) cytology_data: Right limit from inclusion within Df(2L)b83l1 (citation unavailable) product: origin recognition complex subunit genefinder: 59 genscan: 166 match_to: TR G2906228 e-58 H match_to: TR G2739446 e-58 H EST: P1: DS00941 direction: + cDNA_sequence:U43505; g1136136 pr_sequence_SwissProt:Q24169 ems_allele: l(2)34Df¹ l(2)34Df² phenotypic_class: vital. JR_notes: Information on Orc5 from Michelle Pflumme (chez Mike Botchan). SM_notes: Translation from alignment of GenBank U43505. =========================================================================== \+symbol: MtPolB \+formal_name: BG:DS00941.9 synonym: l(2)34De UID: FBgn0020398 UID: FBgn0001962 cytology: 34D8--34E1 cytology_data: Left limit from non-inclusion within Df(2L)b85b2 (citation unavailable) cytology_data: Right limit from non-inclusion within Df(2L)A47 (FBrf0038050) references: FBrf0093778 == Wang et al., 1997, J. Biol. Chem. 272(21): 13640--13646 cDNA_sequence:U94702; g2114434 pr_sequence_TREMBL:O02005 enzyme: mitochondrial DNA-directed DNA polymerase, accessory subunit == EC 2.7.7.7 genefinder: 25/26 genscan: 86 match_to: SP P54098 e-231 H match_to: TR Q92515 e-232 H EST: GM03048.3'; GM03048.5' P1: DS00941 direction: - ems_allele: l(2)34De¹ l(2)34De² l(2)34De³ phenotypic_class: vital. JR_notes: Identity of 34De and MtPolB based on mapping with b89e12 ordering 34De and 34Dg. SM_notes: Translation from alignment of GenBank U94702. =========================================================================== \+symbol: RpII33 \+formal_name: BG:DS00941.10 name: lethal (2) 34Dg synonym: l(2)34Dg UID: FBgn0001964 references: cytology: 34D8--34D8 cytology_data: Left limit from non-inclusion within Df(2L)b85b2 (citation unavailable) cytology_data: Right limit from inclusion within Df(2L)b81l42 (citation unavailable) product: RNA polymerase II 33 KD subunit enzyme: DNA-directed RNA polymerase == EC 2.7.7.6 genefinder: 53 genscan: 161 match_to: GB AF008443 e-105 H match_to: TR O15161 e-107 H match_to: SP P19387 e-106 H match_to: GB D83999 e-100 M match_to: SP P97760 e-101 M match_to: TR Q93338 e-82 W match_to: GB Z81079 e-41 W match_to: GB M27496 e-53 Y match_to: SP P16370 e-56 Y match_to: TR Q39211 e-45 A EST: LD09978.3'; LD09978.5'; LD05121.5'; LD08178.5' P1: DS00941 direction: + ems_allele: l(2)34Dg¹ l(2)34Dg² P_element_allele: l(2)k05605 sequenced phenotypic_class: vital. JR_notes: Information on product & orders from Andrew Hudson (chez Cooley). SM_notes: Translation from full-length LD09978. =========================================================================== \+symbol: BG:DS00941.11 \+formal_name: BG:DS00941.11 genefinder: 47 genscan: 98 product: match_to: EST: P1: DS00941 direction: - SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS00941.12 \+formal_name: BG:DS00941.12 genefinder: 58 genscan: 139 product: match_to: EST: P1: DS00941 direction: - SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS00941.13 \+formal_name: BG:DS00941.13 genefinder: 50 genscan: 113 product: match_to: EST: LP05416.5' P1: DS00941 direction: + SM_notes: Translation from full-length LP05416. ========================================================================== \+symbol: BG:DS00941.14 \+formal_name: BG:DS00941.14 genefinder: 65 genscan: 145 product: match_to: EST: LP05733.5', LP01570.5', LP03350.5' P1: DS00941 direction: + SM_notes: Translation from full-length LP05733. ========================================================================== \+symbol: BG:DS00941.15 \+formal_name: BG:DS00941.15 genefinder: 32 genscan: (43) product: match_to: EST: LP04791.5' P1: DS00941 direction: + SM_notes: Translation from LP04791.5' at 5' end and Genscan at 3' end. ========================================================================== \+symbol: BG:DS08220.1 \+formal_name: BG:DS08220.1 P_element_allele: PZ06646 sequenced rN149 sequenced ms(2)k10802 sequenced not male-sterile genefinder: 127(DS08220) genscan: (22)(DS00941)/298(DS08220) product: match_to: GB D79989 e-103 H (KIAA0167) match_to: TR O00578 e-114 H match_to: GB C08626 e-16 W (worm EST) match_to: GB C08427 e-14 W (worm EST) match_to: TR O04097 e-11 A match_to: GB T04032 e-9 A EST: LD11783.5'; LD11783.3'; GM01069.5'; GM01069.3' P1: DS00941, DS08220 direction: + JR_notes: all excisions of 06646 viable; 2/44 excisions of rN149 are lethal but lethality not to this region (being mapped by JR). SM_notes: Translation from full-length LD11783. n(2)rN149 and PZ06646 map to ex actly the same nucleotide with the same orientation, 4552 of DS00941 (d>p revcomp 76272 of DS00941); ms(2)k10802 maps at 3710 of DS00941. LD11783.5' is from 3699-3125 (d>p revcomp 77325-77899), 1kb downstream of rN149/PZ06646, and 11bp downstream of ms(2)k10802. ========================================================================== \+symbol: anon-34Ea \+formal_name: BG:DS08220.2 references: FBrf0083469 == Tatei et al., 1995, Mech. Dev. 51(2-3): 157--168 P_element_allele: EP(2)2171 sequenced genefinder: 175 genscan: 505 product: match_to: EST: LD02558.3'; LD02558.5'; LD06162.3'; LD06162.5'; LD20278.5'; LD12350.5'; LD22235.5'; LD29084.5' P1: DS08220 direction: - misc_data: 16.5kb EcoRI fragment including the Ance and anon-34Ea genes. SM_notes: Translation from full-length LD02558. EP(2)2171 is inserted at 3159 of DS08220, LD29084.5' first exon is 3139-3164, so P is 5bp upstream of first intron. =========================================================================== \+symbol: Ance \+formal_name: BG:DS08220.3 synonym: l(2)34Eb name: Angiotensin converting enzyme UID: FBgn0012037 references: FBrf0081664 == Cornell et al., 1995, J. Biol. Chem. 270(23): 13613--13619 FBrf0083469 == Tatei et al., 1995, Mech. Dev. 51(2-3): 157--168 FBrf0087131 == Frank and Rushlow, 1996, Development 122(5): 1343--1352 FBrf0090455 == Biehs et al., 1996, Genes Dev. 10(22): 2922--2934 FBrf0092672 == Rusch and Levine, 1997, Development 124(2): 303--311 cytology: 34E2--34E2+ cytology_data: Left limit from inclusion within Df(2L)Adh-nBR55 (FBrf0083469) cytology_data: Right limit from inclusion within Df(2L)b74c6 (citation unavailable) enzyme: peptidyl-dipeptidase A == EC 3.4.15.1 homology: species == Mus; gene == Ace; MGD: MRK-1032 homology: species == Homo sapiens; gene == DCP1; GDB: 119840; OMIM: 106180 genefinder: 41(DS08220)/107(DS00180) genscan: 114(DS08220)/296(DS00180) match_to: SP Q10715 e-71(DS08220)/e-208(DS00180) O (Haematobia irritans) match_to: GB L43965 e-66(DS08220)/e-206(DS00180) O (Haematobia irritans) match_to: SP P22966 e-16(DS08220)/e-101(DS00180) H match_to: GB M26657 e-13(DS08220)/e-99(DS00180) H match_to: GB A31567 e-13(DS08220)/e-99(DS00180) H match_to: GB X16295 e-13(DS08220)/e-99(DS00180) H match_to: GB J04144 e-13(DS08220)/e-173(DS00180) H match_to: GB A00914 e-13(DS08220)/e-173(DS00180) H match_to: SP P22967 e-16(DS08220)/e-106(DS00180) M match_to: SP P09470 e-190(DS00180) M match_to: GB M55333 e-14(DS08220)/e-104(DS00180) M match_to: GB J04946 e-151(DS00180) M match_to: TR Q18581 e-26(DS00180) W EST: LD11258.5'; LD11258.3'; LD06090.5'; LD17344.5'; GM02190.5'; GM01822.5' P1: DS08220, DS00180 direction: + cDNA_sequence:U25344; g1373009 cDNA_sequence:U34599; g1002909 pr_sequence_SwissProt:Q10714 pr_sequence_PIR:A57533 ems_allele: Ance^34Eb-1 Ance^34Eb-2 phenotypic_class: vital. SM_notes: Translation of 3' from aligned GenBank U25344 on DS00180. =========================================================================== symbol: l(2)34Ec JR_notes: predicted by non rescue by Ance transgene of some Ance^- o/laps. =========================================================================== \+symbol: Acyp \+formal_name: BG:DS00180.1 UID: FBgn0025115 references: \x FBrf0104497 == Pieri et al., 1998, FEBS Lett. 433(3): 205--210 enzyme: acyl phosphatase == EC 3.6.1.7 genefinder: 20 genscan: 296* (one span) match_to: SP P56375 e-15 M match_to: SP P07311 e-15 H match_to: GB X84194 e-13 H match_to: GB X84195 e-13 H match_to: GB AA285985 e-13 M (mus EST) EST: P1: DS00180 direction: + pr_sequence_SwissProt:P56544 SM_notes: Translation from Genefinder. ========================================================================== \+symbol: BG:DS00180.2 \+formal_name: BG:DS00180.2 genefinder: 69 genscan: 184 product: match_to: TR Q39721 e-49 O (Euglena gracilis) match_to: TR Q22807 e-9 W EST: P1: DS00180 direction: - SM_notes: Translation from Genefinder. ========================================================================== \+symbol: BG:DS00180.3 \+formal_name: BG:DS00180.3 genefinder: 66 genscan: 142/145(2 spans) product: articulin match_to: TR Q39721 e-49 O (Euglena gracilis) match_to: SP Q02817 e-21 H match_to: YPD 763364 e-19 Y match_to: SP P15265 e-8 M EST: HL02234.5'; HL02234.3' P1: DS00180 direction: - SM_notes: Translation from full-length HL02234. ========================================================================== \+symbol: BG:DS00180.5 \+formal_name: BG:DS00180.5 genefinder: 23/35 genscan: 201(9 spans) product: match_to: SP Q10715 e-203 O match_to: SP P09470 e-190 M match_to: SP P12821 e-187 H match_to: TR Q18581 e-8 W EST: P1: DS00180 direction: + SM_notes: Translation from edited Genscan. ========================================================================== \+symbol: BG:DS00180.12 \+formal_name: BG:DS00180.12 genefinder: 32(3 spans) genscan: 201(3 spans) product: match_to: SP Q61554 e-43 M match_to: SP P35555 e-41 H match_to: TR Q23587 e-22 W EST: GH08194.5'; GH07762.5' P1: DS00180 direction: + SM_notes: Translation from full-length GH07762. ========================================================================== \+symbol: BG:DS00180.7 \+formal_name: BG:DS00180.7 genefinder: 67 genscan: 100 product: tenascin X-like repeat match_to: SP P24821 e-30 H match_to: TR Q08424 e-44 H match_to: TR O35452 e-43 M match_to: SP P98133 e-37 O (cow) match_to: SP P14585 e-13 W match_to: TR O18375 e-29 D EST: HL01444.5'; HL01444.3' P1: DS00180 direction: - SM_notes: Translation from full-length HL01444 =========================================================================== \+symbol: BG:DS00180.8 \+formal_name: BG:DS00180.8 genefinder: 62 genscan: 128 product: tenascin-like repeat match_to: SP P24821 e-30 H match_to: TR Q08424 e-44 H match_to: TR O18375 e-29 D match_to: TR Q64706 e-26 M match_to: TR O01343 e-16 W EST: CK00536.5'; CK00194.5' P1: DS00180 direction: - SM_notes: Translation from full-length CK00536. =========================================================================== \+symbol: BG:DS00180.9 \+formal_name: BG:DS00180.9 genefinder: 30 genscan: 85 product: tenascin/Notch-like repeat match_to: SP P10039 e-31 O (chicken) match_to: TR D1013803 e-15 H match_to: SP Q61554 e-31 M EST: P1: DS00180 direction: + SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS00180.10 \+formal_name: BG:DS00180.10 genefinder: 21 genscan: 120 product: Notch-like repeat match_to: SP Q01705 e-26 M match_to: TR Q23587 e-24 W match_to: TR O18375 e-29 D match_to: HL01967.5' D (Dros EST) EST: LP05465.5' P1: DS00180 direction: - SM_notes: Translation from 5'EST and Genscan. ========================================================================== \+symbol: BG:DS00180.11 \+formal_name: BG:DS00180.11 genefinder: 91(5 spans) genscan: 217(6 spans) product: cytochrome P450 match_to: TR G2673981 e-153 O (D.mettleri) match_to: TR Q64407 e-18 M match_to: SP P33268 e-16 H match_to: HL05525.5' D (Dros EST) EST: P1: DS00180 direction: + SM_notes: Translation from edited Genscan. Cyp28a5 67% identical to Cyp28a1 ========================================================================== \+symbol: BG:DS00180.14 \+formal_name: BG:DS00180.14 genefinder: 91(2 spans) genscan: 217(3 spans) match_to: TR Q15567 e-32 H match_to: TR O18375 e-32 D EST: P1: DS00180 direction: + SM_notes: Translation from edited Genscan. ========================================================================== symbol: j name: jaunty UID: FBgn0001277 references: cytology: 34E3--34E3 cytology_data: Left limit from inclusion within Df(2L)fn26 (FBrf0030161) cytology_data: Right limit from non-inclusion within Df(2L)A376 (FBrf0038050) spontaneous_allele: j² j^49j j^50e j⁵⁸ⁱ ems_allele: j⁶³ j^SF7 misc_allele: j¹ phenotypic_notes: wings upturned. phenotypic_class: visible; non_vital. =========================================================================== \+symbol: rk \+formal_name: BG:DS00180.13 name: rickets UID: FBgn0003255 references: cytology: 34E4--34E5 cytology_data: Left limit from inclusion within Df(2L)fn12 (FBrf0030161) cytology_data: Right limit from inclusion within Df(2L)b-L (FBrf0036112) genefinder: 87/12(DS00180)/26(DS01514) genscan: 207(DS00180)/59(DS01514) product: lutropin/choriogonadotropin receptor match_to: TR U47005 e-77(DS00180) D match_to: TR Q94979 e-77(DS00180) D match_to: GB M73746 e-79(DS00180) H match_to: GB M63108 e-79(DS00180) H match_to: SP P22888 e-82(DS00180) H match_to: SP P30730 e-82(DS00180) M match_to: GB M81310 e-77(DS00180) M match_to: TR Q18759 e-41(DS00180) W match_to: GB Z73971 e-19(DS00180) W match_to: TR O15421 e-9(DS01514) H EST: P1: DS00180, DS01514 direction: - spontaneous_allele: rk⁴ rk⁵ rk^cyl X_ray_allele: rk⁶ gamma_ray_allele: rk^81f2 rk^84b1 UV_allele: rk¹ rk² rk³ ems_allele: rk¹²⁵⁰ rk⁷⁶ rk^80l1 rk^80l2 rk^EMS PM_dysgenesis_allele: rk^Ke1 P_element_allele: rk^11P sequenced misc_allele: rk^AS3 rk^IK6 aberration_associated_allele: rk^noc11 (Df(2L)noc11) phenotypic_notes: legs 'crippled'; tarsal segements short etc. phenotypic_class: visible; non_vital. JR_notes: James Baker (chez Jim Truman) suspects rk to be involved in control of eclosion behaviour by peptide hormones. SM_notes: Translation 5' from Genscan on DS01514, 3' from Genscan on DS00180. rk^11P maps to 9522 of DS01514, sequence from Baker is from 5576-1. =========================================================================== \+symbol: BG:DS01514.3 \+formal_name: BG:DS01514.3 genefinder: genscan: 49 product: match_to: EST: P1: DS01514 direction: + SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS01514.1 \+formal_name: BG:DS01514.1 genefinder: genscan: tRNAscan-SE: 69 product: transfer RNA:gln match_to: GB X68534 e-5 O (rat) EST: P1: DS01514 direction: - Nested_in: BG:DS01514.3 ========================================================================== \+symbol: BG:DS01514.2 \+formal_name: BG:DS01514.2 synonym: 2a9hom P_element_allele: k09909 sequenced genefinder: 93(DS01514)/93(DS00131) genscan: 210(DS01514)/230(DS00131) product: long chain fatty acid CoA-ligase match_to: SP Q10776 e-35(DS01514)/e-42(DS00131) B (Mycobacterium tuberculosis) match_to: TR O30039 e-34(DS01514)/e-40(DS00131) B (Archaeoglobus fulgidus) match_to: GB Z74020 e-22(DS01514)/e-37(DS00131) B (Mycobacterium tuberculosis) match_to: SP P33121 e-28(DS01514)/e-31(DS00131) H match_to: GB D10040 e-23(DS01514)/e-29(DS00131) H match_to: SP P41216 e-27(DS01514)/e-32(DS00131) M match_to: GB U15977 e-31(DS00131) M match_to: TR Q18660 e-20(DS01514)/e-21(DS00131) W match_to: TR Q20264 e-16(DS01514) W match_to: TR G2736373 e-24(DS00131) W match_to: SP P30624 e-23(DS01514) Y match_to: SP P39518 e-23(DS00131) Y match_to: TR O22898 e-25(DS01514)/e-25(DS00131) A EST: LD10778.5'; LD10778.3'; LD02830.5'; HL05723.5'; GM08372.5'; GM14009.5'; GH01357.5'; GH02862.5'; GH02258.5' P1: DS01514, DS00131 direction: + SM_notes: Translation from aligned cDNA sequence from M. Leptin (expressed in anterior mesoderm, later in hemocytes) on DS01514 (5') and DS00131 (3'). ========================================================================== \+symbol: l(2)34Fa \+formal_name: BG:DS05899.2 name: lethal (2) 34Fa UID: FBgn0001967 cytology: 34F2+--34F2+ cytology_data: Left limit from inclusion within Df(2L)Adh-nBR41 (FBrf0091422) cytology_data: Right limit from inclusion within Df(2L)b88f43 (FBrf0092813) genefinder: 37(DS00131)/37(DS05899) genscan: 84(DS00131)/57(DS05899) product: match_to: EST: P1: DS00131, DS05899 direction: - ems_allele: l(2)34Fa¹ l(2)34Fa^CH59 P_element_allele: l(2)34Fa^k00811 sequenced EP(2)2418 sequenced aberration_allele: Df(2L)el20 (hypomorphic) phenotypic_class: vital. SM_notes: Translation from Genscan prediction on DS00131. =========================================================================== \+symbol: BG:DS05899.1 \+formal_name: BG:DS05899.1 synonym: 2a9 genefinder: 87 genscan: 252 product: long chain fatty acid CoA-ligase match_to: GB AL021957 e-46 O (Mycobacterium tuberculosis) match_to: TR E1253260 e-54 O (Mycobacterium tuberculosis) match_to: TR D1032567 e-108 H match_to: SP P41215 e-25 H match_to: SP P41216 e-24 M match_to: TR Q19339 e-19 W match_to: SP P39518 e-16 Y match_to: TR O23268 e-28 A EST: LD28132.5' P1: DS05899 direction: + SM_notes: Translation from aligned cDNA sequence from M. Leptin (expressed in mesoderm and later in fatbody). =========================================================================== \+symbol: BG:DS05899.7 \+formal_name: BG:DS05899.7 genefinder: genscan: 55 product: repeated Leucine-rich segment found in many proteins match_to: TR Q18902 e-27 W match_to: SP P35858 e-21 H match_to: SP P70389 e-21 M match_to: SP P36047 e-14 Y EST: P1: DS05899 direction: - SM_notes: Translation from Genscan prediction. ========================================================================== \+symbol: BG:DS05899.6 \+formal_name: BG:DS05899.6 genefinder: genscan: 46 product: match_to: EST: P1: DS05899 direction: - SM_notes: Translation from Genscan prediction. =========================================================================== \+symbol: BG:DS05899.3 \+formal_name: BG:DS05899.3 genefinder: 42 genscan: 106 product: match_to: SP Q61554 e-8 M (fibrillin precursor) match_to: SP P41990 e-7 W (Apx-1 precursor) EST: P1: DS05899 direction: + SM_notes: Translation from Genscan prediction. =========================================================================== \+symbol: BG:DS05899.5 \+formal_name: BG:DS05899.5 genefinder: genscan: 94 product: match_to: GB L42311 e-12 D (shn) match_to: GB U42403 e-10 D (sr) EST: P1: DS05899 direction: + SM_notes: Translation from Genscan prediction. ========================================================================== \+symbol: BG:DS05899.4 \+formal_name: BG:DS05899.4 genefinder: (14) genscan: 64 product: neuronal acetylcholine receptor, α-7 chain precursor match_to: TR E1246208 e-102 H match_to: SP P36544 e-103 H match_to: SP P49582 e-104 M match_to: GB L37663 e-75 M match_to: SP P48180 e-99 W match_to: GB X83887 e-73 W match_to: SP P09478 e-62 D match_to: HL02253.5' D (Dros EST) EST: P1: DS05899 direction: + SM_notes: Translation from edited Genscan. Not DopR. Region 6.5kb upstream and 2 regions downstream with good homology to receptor but no start codon (stop codon just after nearest M). Removed last 2 exons of Genscan prediction (low prob.) and used for translation. =========================================================================== \+symbol: BG:DS01759.1 \+formal_name: BG:DS01759.1 genefinder: 77 genscan: 192 product: proline-rich region like mucin match_to: TR Q29071 e-11 O (pig) match_to: SP Q02817 e-9 H match_to: SP P37370 e-7 Y EST: P1: DS01759 direction: + SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS01759.2 \+formal_name: BG:DS01759.2 genefinder: (14) genscan: 45 product: match_to: EST: HL03474.5' P1: DS01759 direction: - SM_notes: Translation from full-length HL03474. ========================================================================== \+symbol: BG:DS01523.1 \+formal_name: BG:DS01523.1 genefinder: 112 genscan: 230 product: match_to: GB W26043 e-18 H (Hum EST) EST: P1: DS01523 direction: + SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS01523.2 \+formal_name: BG:DS01523.2 genefinder: 153 genscan: 510 product: repeated segment found in mucin match_to: SP Q02817 e-65 H match_to: TR Q61002 e-21 M match_to: TR O17893 e-51 W match_to: SP P08640 e-46 Y match_to: TR O23054 e-28 A match_to: GB D49534 e-12 D (cno) match_to: LD02410.5' e-6;LD17667.5';LD12158.5';LD34053.5';GM09485.5';LD033260.5';LD23668.5' D (Dros EST) EST: P1: DS01523 direction: - SM_notes: Translation from Genscan. ========================================================================== \+symbol: smi35A \+formal_name: BG:DS01523.3 genefinder: 48/33 genscan: 217 product: Dyrk2 kinase match_to: TR Q92630 e-81 H match_to: SP Q13627 e-48 H match_to: TR Q61214 e-48 M match_to: GB U58497 e-28 M match_to: TR Q20604 e-61 W match_to: SP P14680 e-33 Y EST: CK02015.5'; LD10161.5'; LD10161.3'; LD20817.5'; LD20817.3'; HL01379.5'; HL01379.3'; GM04027.5'; LD02884.5'; LD15788.5'; LD33744.5' P1: DS01523, DS01652, DS03792 direction: - P_element_allele: rff(2)k11509 sequenced smi35A¹ sequenced by Anholt rff(2)k06901 sequenced SM_notes: Translation from full-length LD10161 on DS01523 edited (542-3970), DS01652 (426-541), DS03792 (1-425). k11509 maps to 82600 of DS03792 (first exon), k16716 maps to 53181, smi35A to 53174, and k06901 to 53160 of DS03792. =========================================================================== \+symbol: wb \+formal_name: BG:DS03792.1 synonym: l(2)34Fb name: wing blister UID: FBgn0004002 references: FBrf0046354 == Hilliker and Trusis-Coulter, 1987, Genetics 117: 233--244 cytology: 34F5--34F5 cytology_data: Left limit from inclusion within Df(2L)TE35B-10 (FBrf0091422) cytology_data: Right limit from inclusion within Df(2L)b78j (citation unavailable) genefinder: (14)/(16)/79(DS03792);68/150(DS01068) genscan: 337/(41)(DS03792);565(DS01068) product: laminin-α2 subunit (merosin) match_to: SP P24043 e-128(DS01068) H laminin-α2 match_to: GB X58531 e-112(DS03792) H laminin-α1 match_to: SP P25391 e-112(DS03792)/e-125(DS01068) H laminin-α1 match_to: SP Q60675 e-128(DS01068) M laminin-α2 match_to: GB J04064 e-114(DS03792) M laminin-α1 match_to: SP P19137 e-114(DS03792)/e-122(DS01068) M laminin-α1 match_to: TR E1247268 e-122(DS03792) W laminin-like match_to: SP Q21313 e-95(DS01068) W laminin-like match_to: SP Q00174 e-104(DS01068) D laminin-α EST: CK00390.5'; CK02229.5'; CK02229.3'; CK01592.3' P1: DS03792, DS01068 direction: + cDNA_sequence: AF135118.1 ems_allele: wb¹ wb³ wb⁴ wb^91g2 wb^BMW22 wb^BMW32 wb^CH18 wb^CH20 wb^CH38 wb^CH41 wb^CH57 wb^CH67 wb^CH70 wb^CR1 wb^DM10 wb^GM2 wb^HG10 wb^HG14 wb^HG16 wb^HG17 wb^HG18 wb^HG19 wb^HG24 wb^HG26 wb^HG7 wb^HG9 wb^L412 wb^OK14 wb^PA43 wb^SF19A wb^SF20 wb^SF25 tem_allele: wb^SF11 P_element_allele: wb⁰⁹⁴³⁷ sequenced Baumgartner wb¹⁰⁰⁰² sequenced Baumgartner wb^k06511 cluster: k06520 wb^k08909 wb^k14208 wb^k05612 wb^k00805 wb^k13507 wb^H155 sequenced Baumgartner rL918 sequenced n(2)k16716 sequenced PM_dysgenesis_allele: wb^PI5 X_ray_allele: wb^SF30 gamma_ray_allele: wb^GR301 aberration_associated_allele: wb^6r28 (T(2;3)6r28) wb^DTD121 (In(2LR)DTD121) wb^H68 (T(2;3)H68) misc_allele: wb^IK4 phenotypic_class: behavioural. SM_notes: Translation from alignment of GenBank AF135118.1 on DS03792 (5'; 1-3644) and on DS01068 (3'; 3645-10817). n(2)k16716 (viable over deletion but phenotypically wb) maps to 53181 of DS03792, smi35A to 53174, rff(2)k06901 to 53160, l(2)09437 to 15219, n(2)rL918 to 14850. phenotypic_notes: escapers or weak alleles with wing blister phenotype. phenotypic_class: vital. JR_notes: product data from Baumgartner & Prokop. =========================================================================== symbol: ms(2)34Fe name: male sterile (2) 34Fe synonym: ms(2)34Fh UID: FBgn0002822 references: FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119 cytology: 35A1--35A4 cytology_data: Left limit from complementation mapping against T(2;3)GT10 (citat ion unavailable) cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0091422) misc_allele: ms(2)34Fe¹ phenotypic_class: male_sterile. JR_notes: 34Fe = 34Fh because these classes male sterile (b78j/do-1,b78j/el15,b78j/ms(2)34Fe¹⁷¹⁵,do-1/ms(2)34Fe¹⁷¹⁵,el15/ms(2)34Fe¹⁷¹⁵) and these classes male fertile (b85f1/do-1,b79b4/do-1,b85f1/el15,b79b4/el15,b85f1/ms(2)34Fe¹⁷¹⁵,b79b4/ms(2)34 Fe¹⁷¹⁵) since ms(2)34Fh was inferred from b78j/do-1 and b78j/el15 being ms. =========================================================================== symbol: l(2)34Fc name: lethal (2) 34Fc UID: FBgn0001968 cytology: 35A1--35A4 cytology_data: Left limit from inclusion within Df(2L)A217 (FBrf0038050) cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0038047) gamma_ray_allele: T(2;3)GT10 ems_allele: l(2)34Fc¹ l(2)34Fc² l(2)34Fc³ l(2)34Fc⁴ l(2)34Fc⁵ l(2)34Fc⁶ l(2)34Fc⁷ l(2)34Fc⁸ l(2)34Fc⁹ l(2)34Fc¹⁰ l(2)34Fc^OK9 phenotypic_class: vital. JR_notes: the synthetic deletion GT10 TE35BC-GV8 is hypomorphic for 34Fc, thus GT10 breaks in 34Fc. JR_notes: 3/37 excisions of k08712=Rab14 lethal; all lethal excisions 34Fd^- or 35Aa^-; therefore gene order is 34Fe, 34Fd, Rab14, 35Aa. =========================================================================== symbol: l(2)34Fd name: lethal (2) 34Fd UID: FBgn0001969 references: FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119 cytology: 35A1--35A4 cytology_data: Left limit from inclusion within Df(2L)A217 (FBrf0038050) cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0091422) ems_allele: l(2)34Fd¹ l(2)34Fd² l(2)34Fd³ l(2)34Fd⁴ l(2)34Fd⁵ l(2)34Fd⁶ l(2)34Fd⁷ l(2)34Fd⁸ l(2)34Fd⁹ l(2)34Fd^CH35 phenotypic_class: vital. JR_notes: 3/37 excisions of k08712=Rab14 lethal; all lethal excisions 34Fd^- or 35Aa^-; therefore gene order is 34Fe, 34Fd, Rab14, 35Aa. =========================================================================== \+symbol: BG:DS03792.2 \+formal_name: BG:DS03792.2 genefinder: (20) genscan: 109 product: match_to: LD23113.5' e-7 EST: P1: DS03792 direction: + Nested_in: wb SM_notes: Translation from Genscan. Could be ms(2)34Fe. =========================================================================== \+symbol: BG:DS01068.1 \+formal_name: BG:DS01068.1 genefinder: 100 genscan: 397 product: match_to: EST: P1: DS01068 direction: + SM_notes: Could be ms(2)34Fe or l(2)34Fc. ========================================================================== \+symbol: BG:DS01068.11 \+formal_name: BG:DS01068.11 genefinder: (17)/172(1 span) genscan: 487(2 spans) product: match_to: GB AA313794 e-16 H (Homo EST) match_to: GB AA087241 e-14 M (Mus EST) match_to: SP P34664 e-10 W match_to: LD22379.5' e-22; LD34776.5' e-21; LD31155.5' e-21; LD06669.5' e-21; LD16573.5' e-21;LD16570.5' e-21;LD10017.5' e-21; LD21139.5' e-21;LD17209.5' e-21;LD17733.5' e-21 D (Dros EST) EST: GH05919.3' P1: DS01068 direction: + SM_notes: Translation from edited Genscan on 5' end and G05919.3' on 3' end. Could be ms(2)34Fe or l(2)34Fc. ========================================================================== \+symbol: BG:DS01068.2 \+formal_name: BG:DS01068.2 genefinder: 172(6 spans) genscan: 487(6 spans) product: match_to: TR O01893 e-101 W match_to: TR P73619 e-63 B (Synechoscystis sp.) match_to: GB R13905 e-18 H (Homo EST) match_to: GB T08003 e-18 H (Homo EST) match_to: GB AA451516 e-15 M (Mus EST) match_to: GB T76924 e-11 A (Arab EST) EST: P1: DS01068 direction: + SM_notes: Translation from edited Genscan. Could be ms(2)34Fe or l(2)34Fc. ========================================================================== \+symbol: BG:DS01068.10 \+formal_name: BG:DS01068.10 genefinder: 38 genscan: 30 product: similar to trypsin (serine protease) match_to: SP P15948 e-24 M match_to: SP P42278 e-31 D match_to: SP P54628 e-31 O (Drosophila erecta) EST: P1: DS01068 direction: - SM_notes: Translation from Genscan. Could be ms(2)34Fe or l(2)34Fc. ========================================================================== \+symbol: BG:DS01068.4 \+formal_name: BG:DS01068.4 genefinder: 41 genscan: 92 product: match_to: EST: LD33443.5'; LD22904.5' P1: DS01068 direction: - SM_notes: Translation from full-length LD33443. Could be ms(2)34Fe or l(2)34Fc. ========================================================================== \+symbol: BG:DS01068.5 \+formal_name: BG:DS01068.5 genefinder: 35 genscan: 382 (2 spans) product: match_to: EST: P1: DS01068 direction: - SM_notes: Translation from Genefinder. Could be ms(2)34Fe, l(2)34Fc, or l(2)34Fd. ========================================================================== \+symbol: BG:DS01068.6 \+formal_name: BG:DS01068.6 genefinder: 112 genscan: 382* (4 spans) product: match_to: TR Q19974 e-108 W (worm EST) match_to: SP P48234 e-82 Y match_to: GB Z72930 e-74 Y match_to: GB AA107580 e-41 M (Mus EST) match_to: GB X83354 e-25 M (Mus EST) match_to: GB AA314293 e-33 H (Hum EST) EST: LD09509.3'; LD09509.5'; GM05483.5'; GM06063.5'; GM08820.5'; LD21252.5'; LD32056.5' P1: DS01068 direction: - SM_notes: Translation from full-length LD09509. Best bet for 34Fd. JR_notes: Was thought to be broken by T(2;3)GT10 by in situ with LD09509, but this data disagrees with genetic data showing GT10 breaks in 34Fc. =========================================================================== \+symbol: Rab14 \+formal_name: BG:DS01068.7 full name: Rab-protein 14 synonym: ESTS:57H4T UID: FBgn0015791 cytology: 36A--36B references: FBrf0098074 == Ozaki, 1997.8.1 FBrf0093208 == Satoh et al., 1997, FEBS Lett. 404(1): 65--69 FBrf0077724 == Kohno et al., 1993, Zool. Sci., Tokyo 10: 119 FBrf0080163 == Kohno et al., 1994, Zool. Sci., Tokyo 11: 99 FBrf0086498 == Kono et al., 1995, Zool. Sci., Tokyo 12: 113 P_element_allele: n(2)k08712 sequenced genefinder: 39 genscan: 55 product: Rab14 match_to: SP P35287 e-79 M (rat) match_to: TR Q93874 e-73 W match_to: SP P20338 e-48 H match_to: GB AA214461 e-30 H (Hum EST) match_to: SP P38555 e-36 Y match_to: TR O23657 e-24 A EST: LD03340.3'; LD03340.5'; LD32887.5'; LD29476.5'; LD26806.5' P1: DS01068 direction: + cDNA_sequence: D84316 pr_sequence_SPTREMBL: O18336 phenotypic_class: not vital JR_notes: 3/37 excisions of k08712 lethal; all lethal excisions 34Fd^- or 35Aa^-, indicating that Rab14 is between 34Fd and 35Aa. Since 35Aa- deletion is rescued by a 5-kb GalNac (=35Aa) fragment (from Flores), and P in 5' end of Rab 14, Rab14 not vital. SM_notes: Translation from full-length LD03340 (longer than GenBank D84316). n(2)k08712 inserted at 39329 of DS01068; Rab14 at 39278-42449. =========================================================================== \+symbol: l(2)35Aa \+formal_name: BG:DS01068.8 UID: FBgn0001970 references: FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119 cytology: 35A3--35A4 cytology_data: Left limit from inclusion within Df(2L)TE35B-7 (FBrf0051916) cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0091422) enzyme: polypeptide N-acetylgalactosaminyltransferase == EC 2.4.1.41 genefinder: 107 genscan: 263 match_to: TR Q10471 e-91 H match_to: GB X85019 e-83 H match_to: TR G3047191 e-91 W match_to: TR G3047193 e-91 W match_to: TR G3047195 e-91 W match_to: TR O08912 e-89 M EST: LD24449.5' P1: DS01068 direction: + ems_allele: l(2)35Aa¹ l(2)35Aa² l(2)35Aa³ l(2)35Aa⁴ l(2)35Aa⁵ l(2)35Aa⁶ l(2)35Aa⁷ phenotypic_class: vital. phenotypic_notes: early pupal lethal. SM_notes: Translation from full-length LD24449. JR_notes: Product & transformation rescue information from Flores (chez Engels). =========================================================================== \+symbol: spel1 \+formal_name: BG:DS01068.9 name: spellchecker1 UID: FBgn0015546 references: FBrf0078419 == rd1552 == Flores and Engels, 1995, A. Conf. Dros. Res. 36: 204A cytology: 35A1--35A1 cytology_data: Left limit from inclusion within Df(2L)A217 (FBrf0038050) cytology_data: Right limit from sequence databank entry U17893 genefinder: 83(DS01068);33(DS06238) genscan: 211(DS01068);33(DS06238) match_to: SP P43246 e-97(DS01068)/e-70(DS06238) H match_to: GB U04045 e-84(DS01068)/e-64(DS06238) H match_to: SP P43247 e-92(DS01068)/e-68(DS06238) M match_to: TR O24617 e-60(DS01068)/e-56(DS06238) A match_to: SP P25847 e-50(DS01068)/e-60(DS06238) Y EST: LD33650.5'; GM13404.5'; LD14009.5' P1: DS01068, DS06238 direction: + motifs: PS00486 == DNA mismatch repair proteins mutS family signature. homology: species == Escherichia coli; gene == mutS; ECOGENE: EG10625 homology: species == Mus; gene == Msh2; MGD: MRK-18634 homology: species == Homo sapiens; gene == MSH2; GDB: 203983; OMIM: 120435 cDNA_sequence:U17893; g675456 partial pr_sequence_SwissProt:P43248 phenotypic_class: non_vital. SM_notes: Translation from alignment of GenBank U17893 on DS01068 & DS06238. =========================================================================== \+symbol: ppk \+formal_name: BG:DS06238.1 name: pickpocket synonym: mdNaC1 UID: FBgn0020258 cDNA_sequence: Y16225; e1237841 cDNA_sequence: AF043263; g2811254 pr_sequence_TREMBL:O46104 pr_sequence_TREMBL:O44940 genefinder: (9)/28 genscan: 132 product: epithelial sodium channel. match_to: TR AF043264 e-61 D EST: P1: DS06238 direction: - SM_notes: Translation from alignment of GenBank on AF043263. ========================================================================== \+symbol: elB \+formal_name: BG:DS06238.3 name: elbow B UID: FBgn0004858 references: FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119 cytology: 35A4--35A4 cytology_data: Left limit from inclusion within Df(2L)TE35B-14 (FBrf0092813) cytology_data: Right limit from inclusion within Df(2L)b83d29a (FBrf0051916) genefinder: 74 genscan: 199 product: noc-like Zinc-finger protein match_to: TR Q24423 e-59 D match_to: TR Q41805 e-7 O (Zea mays) EST: P1: DS06238 direction: - spontaneous_allele: see elA ems_allele: see elA gamma_ray_allele: see elA elB⁸ X_ray_allele: aberration_associated_allele: elB⁴ (T(Y;2)el⁴) elB⁶ (In(2LR)el⁶) elB⁷ (T(2;3)dpp^s19) elB⁹ (In(2L)el⁹) elB⁵ (T(Y;2)a15) P_element_allele: EP(2)2039 sequenced (elbow over a deletion) EP(2)0965 sequenced k07706 sequenced phenotypic_notes: reduced posterior compartment in wing; very similar, but complements, elA. SM_notes: Translation from Genscan. EP(2)2039 & sequence from Cohen at 45657 of DS06238; EP(2)0965 at 45828; k07706 at 45738. ========================================================================== \+symbol: BG:DS06238.4 \+formal_name: BG:DS06238.4 genefinder: 30 genscan: 63 product: larval cuticle protein match_to: GB M71249 e-11 D (Edg84A) match_to: SP P04929 e-33 O (Plasmodium lophurae) (His-rich, repeat segment) match_to: TR Q92504 e-11 H (His-rich, repeat segment) match_to: TR D1012195 e-11 H (His-rich, repeat segment) match_to: SP Q31125 e-11 M (His-rich, repeat segment) match_to: TR O35957 e-11 M match_to: TR O18272 e-9 W EST: P1: DS06238 direction: - SM_notes: Translation from Genscan. MA_notes: Best bet for pu, since matches Edg84A. ========================================================================== \+symbol: BG:DS08340.1 \+formal_name: BG:DS08340.1 genefinder: (9) genscan: (42) product: match_to: GB AA419695 e-8 M (Mus EST) match_to: GB AA778038 e-8 H (Hum EST) match_to: GH12842.5' e-19; LP06079.5' e-19; LP02268.5' e-19; GH06541.5' e-19; GH10679.5' e-19 D EST: P1: DS08340 direction: - SM_notes: Translation from Genscan. MA_notes: Best bet for elA. ========================================================================== symbol: pu name: pupal UID: FBgn0003161 references: FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119 cytology: 35B1--35A4+ cytology_data: Left limit from complementation mapping against T(2;3)GT3 (citation unavailable) cytology_data: Right limit from inclusion within Df(2L)b83d29a (FBrf0051916) spontaneous_allele: pu¹ ems_allele: pu² pu³ pu⁴ pu⁵ pu⁶ pu⁷ phenotypic_notes: wings unexpanded. phenotypic_class: visible; non_vital. =========================================================================== symbol: elA name: elbow A UID: FBgn0004857 references: FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119 cytology: 35B1--35B1 cytology_data: Left limit from inclusion within Df(2L)ARR1 (FBrf0051916) cytology_data: Right limit from inclusion within Df(2L)b81a1 (FBrf0038047) spontaneous_allele: elA¹ (25-kb deletion) ems_allele: elA² elA³ elA²¹ elA²² elA²³ elA²⁷ elA²⁹ elA³⁰ gamma_ray_allele: elA⁸ elA¹⁰ elA¹¹ elA¹² elA²⁵ elA²⁶ aberration_associated_allele: elA²⁴ (T(2;3)el24) phenotypic_notes: reduced posterior compartment in wing; very similar, but complements, elB. phenotypic_class: visible; non_vital. =========================================================================== \+symbol: noc \+formal_name: BG:DS04641.1 name: no ocelli UID: FBgn0005771 references: FBrf0066938 == Cheah et al., 1994, Molec. Cell. Biol. 14: 1487--1499 FBrf0043115 == Chia et al., 1985, J. molec. Biol. 186: 689--706 FBrf0087599 == McNabb et al., 1996, Genetics 143(2): 897--911 cytology: 35B1+--35B1+ cytology_data: Left limit from inclusion within Df(2L)A178 (FBrf0038047) cytology_data: Right limit from inclusion within Df(2L)b81a1 (FBrf0038047) motifs: Zinc finger protein. genefinder: 88 genscan: 179 match_to: TR Q90237 e-11 O (Anolis pulchellus) match_to: SP P32323 e-7 Y EST: GM07914.5'; LD28078.5'; LD28077.5' P1: DS04641 direction: + cDNA_sequence:L14009; g457883 pr_sequence_TREMBL:Q24423 pr_sequence_PIR:A55929 ems_allele: noc¹⁸ noc¹⁹ noc²² noc²³ noc^35Ba-1 noc^35Ba-2 noc^35Ba-3 noc^35Ba-4 noc^Sco-rv15 TE_insert_allele: noc^TE35B (TE146) X_ray_allele: noc^Sco-rv27 gamma_ray_allele: noc¹⁴ noc¹⁵ noc²¹ noc⁶ aberration_associated_allele: noc² (In(2L)noc²) noc⁴ (In(2LR)noc⁴) noc⁷ (In(2LR)noc⁷) noc^GT8 (T(2;3)GT8) noc^Sco (Tp(2;2)Sco) noc^Sco-rv1 (In(2LR)Sco^rv1) noc^Sco-rv2 (In(2L)Sco^rv2) noc^Sco-rv5 (In(2L)Sco^rv5) noc^Sco-rv8 (In(2L)Sco^rv8) noc^Sco-rv9 (In(2LR)Sco^rv9) noc^Sco-rv11 (In(2L)Sco^rv11) noc^Sco-rv12 (Tp(2;2)Sco^rv12) noc^Sco-rv13 (T(2;3)Sco^rv13) noc^Sco-rv17 (In(2L)Sco^rv17) noc^Sco-rv21 (In(2L)Sco^rv21) noc^Sco-rv23 (Tp(2;1)Sco^rv23) noc^Sco-rv24 (In(2L)Sco^rv24) noc^Sco-rv26 (In(2L)Sco^rv26) TE146 derivatives P_element_allele: EP(2)2000 sequenced EP(2)2173 sequenced phenotypic_notes: visible phenotype is loss of ocelli; lethal may show failure of head involution; Sco is antimorphic allele. phenotypic_class: vital. SM_notes: Translation from alignment of GenBank L14009. =========================================================================== \+symbol: BG:DS04641.2 \+formal_name: BG:DS04641.2 genefinder: genscan: tRNAscan-SE: 57 product: tRNA-pro match_to: (GB M26848 e-6 M) EST: P1: DS04641 direction: + ========================================================================== \+symbol: tRNA:G3:35Ba \+formal_name: BG:DS04641.3 name: transfer RNA:gly3: 35Ba UID: FBgn0011862 references: FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189 cytology: 35B1--35B2 genefinder: genscan: tRNAscan-SE: 72 product: tRNA-gly3 match_to: (GB Z14135 e-6 O (Bombyx mori)) match_to: (GB Z15047 e-6 O (Bombyx mori)) EST: P1: DS04641 direction: + na_sequence:X07778 =========================================================================== \+symbol: tRNA:G3:35Bb \+formal_name: BG:DS04641.4 name: transfer RNA:gly3: 35Bb UID: FBgn0011863 references: FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189 cytology: 35B1--35B2 genefinder: genscan: tRNAscan-SE: 72 product: tRNA-gly3 match_to: GB M13661 e-9 H match_to: GB Z49226 e-12 O (Bombyx mori) match_to: TR O17337 e-8 W EST: P1: DS04641 direction: - na_sequence:X07778 =========================================================================== \+symbol: tRNA:G3:35Bc \+formal_name: BG:DS04641.5 name: transfer RNA:gly3: 35Bc UID: FBgn0011864 references: FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189 cytology: 35B1--35B2 genefinder: genscan: tRNAscan-SE: 72 product: tRNA-gly3 match_to: GB M13661 e-9 H match_to: GB Z49226 e-12 O (Bombyx mori) EST: P1: DS04641 direction: - na_sequence:X07779 =========================================================================== \+symbol: tRNA:G3:35Bd \+formal_name: BG:DS04641.6 name: transfer RNA:gly3: 35Bd UID: FBgn0011865 references: FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189 cytology: 35B1--35B2 genefinder: genscan: tRNAscan-SE: 72 product: tRNA-gly3 match_to: GB M13661 e-9 H match_to: GB Z49226 e-12 O (Bombyx mori) EST: P1: DS04641 direction: - na_sequence:X07779 =========================================================================== \+symbol: tRNA:G3:35Be \+formal_name: BG:DS04641.7 name: transfer RNA:gly3: 35Be UID: FBgn0011866 references: FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189 cytology: 35B1--35B2 genefinder: genscan: tRNAscan-SE: 68 product: tRNA-gly3 match_to: GB M13661 e-9 H match_to: GB Z49226 e-12 O (Bombyx mori) EST: P1: DS04641 direction: - na_sequence:X07779 ========================================================================== \+symbol: BG:DS04641.8 \+formal_name: BG:DS04641.8 genefinder: 27 genscan: 94 product: match_to: EST: P1: DS04641 direction: - SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS01486.1 \+formal_name: BG:DS01486.1 genefinder: (8) genscan: (44) product: ubiquitin--protein ligase match_to: SP Q16781 e-60 H match_to: SP P52490 e-50 Y match_to: GB AA271547 e-45 M (Mus EST) match_to: GB U62483 e-26 M match_to: SP P35129 e-31 W match_to: GB S70118 e-44 D match_to: GB L20126 e-44 D match_to: SP P35132 e-30 A match_to: LD24448.5' e-43; LD16328.c e-43; GM02759.5' e-43;LD14534.5'e-40; LD31794.5' e-35 EST: P1: DS01486 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS01486.2 \+formal_name: BG:DS01486.2 genefinder: genscan: tRNAscan-SE: 57 product: transfer RNA:pro match_to: GB X55888 e-9 O (chicken) EST: P1: DS01486 direction: + ========================================================================== \+symbol: BG:DS01486.3 \+formal_name: BG:DS01486.3 genefinder: genscan: tRNAscan-SE: 57 product: transfer RNA:pro match_to: GB X55888 e-10 O (chicken) EST: P1: DS01486 direction: - ========================================================================== \+symbol: BG:DS01486.4 \+formal_name: BG:DS01486.4 genefinder: genscan: tRNAscan-SE: 57 product: transfer RNA:pro match_to: GB X55888 e-9 O (chicken) EST: P1: DS01486 direction: + ========================================================================== \+symbol: osp \+formal_name: BG:DS01486.7 synonym: BG:DS01486.5 synonym: BG:DS07721.2 name: outspread UID: FBgn0003016 references: FBrf0087599 == McNabb et al., 1996, Genetics 143(2): 897--911 cytology: 35B3--35B3 cytology_data: Left limit from complementation mapping against T(2;3)GT7 (citation unavailable) cytology_data: Right limit from inclusion within Df(2L)A178 (FBrf0038047) genefinder: 94/34(DS01486); 9(DS07721) genscan: 431(DS01486); (30)* (2 spans)(DS07721) match_to: TR P97434 e-18 M (p116Rip) match_to: GB AA118415 e-10 M (Mus EST) match_to: SP P11055 e-10 H (myosin heavy chain) match_to: SP P13535 e-10 H (myosin heavy chain) match_to: TR Q20042 e-10 W match_to: TR Q18082 e-9 W (myosin heavy chain) match_to: SP P25386 e-8 Y EST: LD14119.5'; LD14119.3'; LD13781.5'; CK02594.5'; LD15891.5'; LD15891.3' P1: DS01486, (DS09219), DS07721 direction: - na_sequence:M14802; g552081 na_sequence:M17837; g903720 na_sequence:Z00030; g7559 pr_sequence_TREMBL:Q24231 pr_sequence_TREMBL:Q27421 ems_allele: osp¹ osp¹⁶ osp¹⁹ osp²⁴ osp²⁵ osp²⁷ osp⁴ osp⁶ osp⁷ osp^76e osp^77e osp⁸ osp^CH63 diepoxyoctane_allele: osp^80.1D P_element_allele: osp^rJ571 sequenced l(3)00865 sequenced k13218 sequenced gamma_ray_allele: osp¹⁰⁴ osp²⁰¹ osp²⁹ osp³⁵ osp⁴⁰ osp⁸³ aberration_associated_allele: osp²² (In(2L)osp²²) osp³ (Tp(2;3)osp³) osp²⁹ (Df(2L)osp29) osp⁵⁹ (In(2L)osp⁵⁹) osp⁹⁰ (T(2;3)osp⁹⁰) osp^H47 (T(2;3)H47) osp^Mpe (T(2;3)Mpe) osp^pb3 (T(2;3)pb³) osp^H86 (In(2L)dpp^H86) misc_allele: osp^alw phenotypic_notes: wings outspread; not vital. phenotypic_class: visible; non_vital. MA_notes: includes BG:DS01486.6; Note that k13218 is not a phenotypic osp allele. SM_notes: Appears to be alternatively spliced: translation of osp-LD14119 from complete sequence LD14119 (not full-length on 5' end?), doesn't use penultimate exon of LD15891 but does use last exon (longer 3'). Translation of osp-3prime from full-length LD15891 on DS01486 (838-5324), osp-5prime on DS07721. =========================================================================== \+symbol: Adh \+formal_name: BG:DS01486.8 name: Alcohol dehydrogenase UID: FBgn0000055 cytology: 35B3--35B3 cytology_data: Left limit from non-inclusion within Df(2L)TE35B-8 (FBrf0087599) cytology_data: Right limit from inclusion within Df(2L)A178 (FBrf0038047) enzyme: alcohol dehydrogenase == EC 1.1.1.1 genefinder: genscan: 132* (1 span) match_to: SP P15428 e-11 H match_to: TR Q61106 e-10 M EST: HL01670.5'; HL05782.5'; GH01616.5' P1: DS01486 direction: + motifs: PS00061 == Short-chain alcohol dehydrogenase family signature. na_sequence:J01066 na_sequence:M14802; g156803 na_sequence:M17827; g156860 na_sequence:M17828; g156862 na_sequence:M17830; g156866 na_sequence:M17831; g156868 na_sequence:M17832; g156870 na_sequence:M17833; g156872 na_sequence:M17834; g156874 na_sequence:M17835; g156876 na_sequence:M17836; g156878 na_sequence:M17837; g156880 na_sequence:M17845; g156906 na_sequence:M19547; g156864 na_sequence:M22210; g156839 na_sequence:M29635 na_sequence:M29636; e124826 na_sequence:M36580; g156805 na_sequence:M57239; g156800 na_sequence:M71284 na_sequence:M73256 na_sequence:U20765; g684944 na_sequence:U35852 na_sequence:X04454 na_sequence:X15607 na_sequence:X60791; g8152 na_sequence:X60792; g8441 na_sequence:X60793; g8282 na_sequence:X66233 na_sequence:X78384; e315259 na_sequence:X78385 na_sequence:X78386 na_sequence:X78387 na_sequence:X78402 na_sequence:X78916 na_sequence:X78917 na_sequence:X98338; e248823 na_sequence:Z00030; g599727 pr_sequence_SwissProt:P00334 pr_sequence_TREMBL:Q27332 pr_sequence_TREMBL:Q27579 pr_sequence_TREMBL:Q27596 pr_sequence_PIR:A37092 pr_sequence_PIR:B93309 pr_sequence_PIR:A93713 pr_sequence_PIR:A93875 pr_sequence_PIR:A93309 pr_sequence_PIR:A93873 pr_sequence_PIR:S17083 pr_sequence_PIR:S17084 phenotypic_class: visible; non_vital. Nested_in: osp SM_notes: Translation from alignment of trEMBL Q27332. =========================================================================== \+symbol: Adhr \+formal_name: BG:DS01486.9 name: Adh-related UID: FBgn0000056 references: Brogna, EMBO J. 16: 2023-2031 cytology: 35B3--35B3 cytology_data: Left limit from non-inclusion within Df(2L)TE35B-8 (FBrf0091422) cytology_data: Right limit from inclusion within Df(2L)A178 (FBrf0091422) genefinder: (15) genscan: 132* (2 spans) product: alcohol-dehydrogenase \like match_to: SP P15428 e-11 H match_to: TR Q61106 e-10 M EST: GM04306.5' P1: DS01486 direction: + na_sequence:M14802; g765036 na_sequence:Z00030 na_sequence:X78384; g483719 na_sequence:X98338; e248898 pr_sequence_TREMBL:Q24230 pr_sequence_TREMBL:Q24232 phenotypic_notes: complete deletion associated with malformation of gastric caecea. phenotypic_class: visible; non_vital. Nested_in: osp SM_notes: Translation from alignment of SwissProt P91615. ========================================================================== \+symbol: BG:DS09219.1 \+formal_name: BG:DS09219.1 genefinder: genscan: (41)(DS09219)/(34)(DS07721) product: match_to: EST: P1: DS09219, DS07721 direction: - Nested_in: osp SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS07721.1 \+formal_name: BG:DS07721.1 genefinder: genscan: product: match_to: EST: CK02594.5'; CK02594.3' P1: DS07721 direction: + Nested_in: osp SM_notes: Translation from full-length CK02594. =========================================================================== \+symbol: BG:DS07721.3 \+formal_name: BG:DS07721.3 genefinder: 21 genscan: 47/(44) product: match_to: LP02495.5' e-8; LP04185.5' e-8; LP03565.5' e-8; LP03436.5' e-8 EST: P1: DS07721 direction: + SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS07721.6 \+formal_name: BG:DS07721.6 genefinder: genscan: 271 match_to: EST: P1: DS07721 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS00810.1 \+formal_name: BG:DS00810.1 genefinder: 25 genscan: 97 product: match_to: GB AA313794 e-14 H (Homo EST) match_to: SP P34664 e-14 W match_to: GB AA087241 e-10 M (Mus EST) match_to: LD20357.5' e-13;LD22379.5' e-12;LD34776.5' e-12;LD31155.5' e-12;LD16573.5' e-12;LD16570.5' e-12;LD06669.5' e-12;LD21139.5' e-12;LD28856.5' e-12;LD15550.5' e-12 EST: P1: DS00810 direction: + SM_notes: Translation from Genscan. ========================================================================== \+symbol: BG:DS00810.2 \+formal_name: BG:DS00810.2 genefinder: (19) genscan: product: ribosomal protein 15a match_to: GB Z21673 e-47 D match_to: LD11847.3' e-25; GM02304.5' e-27; GM04832.5' e-25; GM06369.5' e-54; GM13983.5' e-48; HL07857.5' e-43; LD03678.5' e-25; LD04294.5' e-21; LD07181.5' e-50; LD14972.5' e-25; LD33594.5' e-48; GH04971.3' e-45 EST: LP03565.5'; LP04185.5'; LP02495.5'; LP04636.3'; LP06216.3'; LP03436.5' P1: DS00810 direction: - SM_notes: Translation from full-length LP03565. ========================================================================== \+symbol: BG:DS00810.3 \+formal_name: BG:DS00810.3 genefinder: (16) genscan: (14) product: match_to: SP Q25055 e-10 O match_to: SP P17816 e-12 O match_to: TR O02049 e-9 W EST: GH13704.5'; GH07880.5'; LP02868.5'; LP03582.5' P1: DS00810 direction: + SM_notes: Translation from complete sequence GH13704 at 5' (not full-length clone?) and GH07880.5' EST at 3'.. =========================================================================== \+symbol: BG:DS06874.1 \+formal_name: BG:DS06874.1 genefinder: 27 genscan: 59 product: match_to: EST: P1: DS06874 direction: + SM_notes: Translation from Genefinder. ========================================================================== \+symbol: BG:DS06874.2 \+formal_name: BG:DS06874.2 genefinder: (19) genscan: 111 product: match_to: SP P97834 e-58 (rat) match_to: GB X87885 e-57 (rat) match_to: SP Q13098 e-56 H match_to: SP P45432 e-37 A match_to: GB W65922 e-13 M (Mus EST) EST: P1: DS06874 direction: + SM_notes: Translation from Genscan. MA_notes: Fusca; GPS1 homolog see MCB 16: 6698-6706 =========================================================================== \+symbol: BG:DS06874.3 \+formal_name: BG:DS06874.3 genefinder: 44 genscan: 127 product: MSP1 homolog (TAT-binding) match_to: SP P54815 e-62 W match_to: YPD 1323004 e-62 Y match_to: GB X68055 e-56 Y match_to: GB X81069 e-58 Y match_to: TR G3193292 e-50 A match_to: GB AA028745 e-36 M (Mus EST) match_to: GB AA268776 e-36 M (Mus EST) match_to: TR G2984586 e-33 H match_to: TR G3283072 e-33 H match_to: SP P91638 e-33 D match_to: GH13949.5' e-58; LP05581.5' e-39; GH08677.5' e-39; LD20618.5' e-22;GM07738.5' e-12;GM05721.5' e-15;GM04824.5' e-12;CK00306.5' e-28 EST: P1: DS06874 direction: + SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS06874.4 \+formal_name: BG:DS06874.4 genefinder: (16) genscan: 103(2 spans) product: serine protease match_to: SP P40313 e-13 H match_to: TR D1029835 (AB015206) e-11 M match_to: SP P05049 e-10 D EST: P1: DS06874 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS06874.6 \+formal_name: BG:DS06874.6 genefinder: genscan: (35) product: serine protease match_to: TR D1029835 (AB015206) e-8 M match_to: SP P40313 e-13 H EST: P1: DS06874 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS06874.7 \+formal_name: BG:DS06874.7 genefinder: genscan: 119 product: match_to: EST: P1: DS06874 direction: + SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS03431.1 \+formal_name: BG:DS03431.1 genefinder: 55 genscan: 111 product: proline transporter match_to: TR G3252836 e-115 O (tobacco hornworm) match_to: SP P51905 e-74 D match_to: SP Q99884 e-69 H match_to: TR Q99884 e-69 H match_to: SP P31659 e-63 M match_to: TR O17372 e-54 W match_to: LD18557.5' e-31 EST: P1: DS03431 direction: - SM_notes: Translation from Genscan. ether resistant P-element insert; may or may-not be this. =========================================================================== \+symbol: Mst35Ba \+formal_name: BG:DS03431.2 name: Male-specific-transcript-35Ba references: FBrf0058368 == Russell and Kaiser, 1993, Europ. Dros. Res. Conf. 13: n.p. cytology: 35B1--35B10 genefinder: genscan: product: protamine \like match_to: SP P17502 e-7 O (boll weevil) EST: P1: DS03431 direction: - cDNA_sequence:Z46790; g608696 genomic_sequence:Z46783; g608700 pr_sequence_TREMBL:Q24401 pr_sequence_TREMBL:Q24405 pr_sequence_PIR:S52155 pr_sequence_PIR:S52157 SM_notes: Translation from GenBank Z46790. =========================================================================== \+symbol: Mst35Bb \+formal_name: BG:DS03431.3 name: Male-specific-transcript-35Bb references: FBrf0058368 == Russell and Kaiser, 1993, Europ. Dros. Res. Conf. 13: n.p. cytology: 35B1--35B10 genefinder: (11) genscan: product: protamine \like match_to: EST: P1: DS03431 direction: - cDNA_sequence:Z46784; g608698 genomic_sequence:Z46785; g608702 pr_sequence_TREMBL:Q24402 pr_sequence_TREMBL:Q24406 pr_sequence_PIR:S52156 pr_sequence_PIR:S52158 SM_notes: Translation from GenBank Z46784. =========================================================================== symbol: ms(2)35Bi JR_notes: Inferred from deletion o/laps. =========================================================================== \+symbol: BG:DS03144.1 \+formal_name: BG:DS03144.1 genefinder: 49/(11) genscan: 123 product: match_to: EST: P1: DS03144 direction: - SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS03323.1 \+formal_name: BG:DS03323.1 genefinder: 102(DS03323) genscan: 133(DS03144);405(DS03323) product: strawberry-notch-like match_to: GB U95760 e-197 D (sno) match_to: TR O01737 e-241 W match_to: TR G3152595 e-176 A match_to: GB AA413592 e-51 M (Mus EST) match_to: GB W25975 e-31 H (Hum EST) match_to: HL01650.5' e-24 EST: P1: DS03144, DS03323 direction: + SM_notes: Translation from Genscan. =========================================================================== \+symbol: BG:DS01219.3 \+formal_name: BG:DS01219.3 genefinder: (10) genscan: 99 product: match_to: EST: P1: DS01219 direction: - SM_notes: Translation from Genscan. =========================================================================== symbol: l(2)35Bb name: lethal (2) 35Bb UID: FBgn0001972 references: FBrf0087599 == McNabb et al., 1996, Genetics 143(2): 897--911 cytology: 35B4--35B4 cytology_data: Left limit from inclusion within Df(2L)TE35BC-34 (FBrf0091422) cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544) spontaneous_allele: l(2)35Bb⁶ ems_allele: l(2)35Bb¹ l(2)35Bb² l(2)35Bb³ l(2)35Bb⁴ l(2)35Bb⁵ l(2)35Bb⁷ l(2)35Bb⁸ l(2)35Bb⁹ neutron_induced_allele: l(2)35Bb¹⁰ P_element_induced_allele: l(2)35Bb^k11524 sequenced(DS00929) phenotypic_class: vital. SM_notes: k11524p inserted at 5037 of DS00929, in ORF of BG:DS00929.16, but BG:DS01219.1 ESTs from 1533-1359 of DS00929. =========================================================================== symbol: l(2)35Bf name: lethal (2) 35Bf UID: FBgn0001976 references: cytology: 35B4--35B4 cytology_data: Left limit from inclusion within Df(2L)TE35BC-4 (FBrf0038053) cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544) ems_allele: l(2)35Bf¹ l(2)35Bf² l(2)35Bf³ l(2)35Bf⁴ l(2)35Bf⁵ l(2)35Bf⁶ l(2)35Bf⁷ l(2)35Bf⁸ l(2)35Bf^QL53 phenotypic_class: vital. JR_notes: Excision of k08808=l(2)35Bc indicates gene order is 35Bb, 35Bf, 35Be, 35Bc, 35Bd. ========================================================================== symbol: l(2)35Be name: lethal (2) 35Be UID: FBgn0001975 references: cytology: 35B4--35B4 cytology_data: Left limit from inclusion within Df(2L)TE35BC-4 (FBrf0038053) cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544) ems_allele: l(2)35Be¹ l(2)35Be² l(2)35Be³ l(2)35Be⁴ l(2)35Be⁵ l(2)35Be⁶ l(2)35Be⁷ phenotypic_class: vital. JR_notes: Excision of k08808=l(2)35Bc indicates gene order is 35Bb, 35Bf, 35Be, 35Bc, 35Bd. =========================================================================== symbol: l(2)35Bc name: lethal (2) 35Bc UID: FBgn0001973 references: cytology: 35B4--35B4 cytology_data: Left limit from inclusion within Df(2L)TE35BC-4 (FBrf0038053) cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544) ems_allele: l(2)35Bc¹ l(2)35Bc² l(2)35Bc³ l(2)35Bc⁴ l(2)35Bc⁵ l(2)35Bc⁶ l(2)35Bc⁷ l(2)35Bc⁸ P_element_allele: l(2)35Bc^k08808 sequenced phenotypic_class: vital. SM_notes: yoyo is in intron of l(2)35Bb; P sequences map to yoyo LTRs (therefore nested in 35Bb).. The following P-elements match the sequence of the yoyo LTR but some may be from other sites: l(3)06264, l(2)01092, EP(x)1031, l(2)rH280, l(2)k00611, EP(2)0533, EP(3)0396, EP(x)1102, l(3)j2D5, l(3)rL061 JR_notes: Of 84 viable and 38 lethal excisions of k08808, 3 are deletions: 1 mutant for 35Be and 35Bc, 2 mutant for 35Bc and 35Bd. This suggests order is 35Bb, 35Bf, 35Be, 35Bc, 35Bd. PZ06264 is a 2nd site insertion. =========================================================================== \+symbol: BG:DS01219.1 \+formal_name: BG:DS01219.1 genefinder: 40/9 genscan: 53(2 spans)/37(1 span)(DS01219) product: match_to: SP P34298 e-11 W EST: LD16050.5'; LD16050.3'; LD13118.5'; LD13118.3'; LD14488.5'; LD17401.5'; LD27791.5' P1: DS01219, DS00929 direction: - SM_notes: Translation from full-length LD16050 3' on DS01219 (166-1993), 5' on DS00929 (1-165). k11524p (l(2)35Bb) inserted at 5037 of DS00929, ESTs from 1533-1359 of DS00929, so could be l(2)35Bb. =========================================================================== \+symbol: BG:DS00929.16 \+formal_name: BG:DS01219.16 genefinder: genscan: 71 product: match_to: EST: P1: DS00929 direction: + SM_notes: Translation from 5' edited Genscan (missing 5' end?). Good bet for l(2)35Bb because P element k11524p maps to 5037 of DS00929 and one ORF of genscan prediction is 4992-5160. JR_notes: Could also be l(2)35Bf. =========================================================================== \+symbol: BG:DS00929.1 \+formal_name: BG:DS00929.1 genefinder: 21 genscan: 49 product: match_to: GB AA221255 e-32 M (Mus EST) match_to: GB AA245336 e-32 M (Mus EST) match_to: GB AA166258 e-32 M (Mus EST) match_to: GB AA25934 e-27 H (Hum EST) match_to: GB AA004508 e-10 H (Hum EST) EST: P1: DS00929 direction: + SM_notes: Translation from Genscan. Could be l(2)35Bf or l(2)35Be. ========================================================================== \+symbol: BG:DS00929.2 \+formal_name: BG:DS00929.2 genefinder: 43 genscan: 75 product: ankyrin-like match_to: GB AA200445 e-17 M (Mus EST) match_to: GB AA200439 e-17 M (Mus EST) match_to: TR Q19822 e-14 W match_to: SP P16157 e-10 H match_to: TR Q24241 e-7 D EST: LD17234.5'; LD17234.3' P1: DS00929 direction: - SM_notes: Translation from full-length LD17234. Could be l(2)35Bf, l(2)35Be, or l(2)35Bc. =========================================================================== \+symbol: BG:DS00929.3 \+formal_name: BG:DS00929.3 genefinder: 44 genscan: 70 product: TATA-binding protein associated phosphoprotein match_to: SP Q01658 e-33 H match_to: GB M97388 e-31 H match_to: GB AA413894 e-31 M (Mus EST) match_to: TR E1246915 e-19 W match_to: SP P49592 e-17 A match_to: TR Q92317 e-10 Y match_to: YPD 1666487 e-16 Y EST: P1: DS00929 direction: + SM_notes: Translation from Genscan. Could be l(2)35Be or l(2)35Bc. ========================================================================== \+symbol: BG:DS00929.4 \+formal_name: BG:DS00929.4 genefinder: 29 genscan: 62 product: match_to: SP P53215 e-56 Y match_to: GB Z72809 e-55 Y match_to: GB T04261 e-29 A match_to: GB AA450700 e-23 M (Mus EST) match_to: GB W77781 e-7 H (Hum EST) EST: P1: DS00929 direction: - SM_notes: Translation from Genscan. Could be l(2)35Bc. =========================================================================== \+symbol: l(2)35Bd \+formal_name: BG:DS00929.5 name: lethal (2) 35Bd UID: FBgn0001974 references: cytology: 35B4--35B4 cytology_data: Left limit from inclusion within Df(2L)Antp^Ctxrv1 (FBrf0092813) cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544) genefinder: 49 genscan: 684(2 spans) product: mRNA cap methyltransferase match_to: TR D1024575 e-72 H match_to: SP P32783 e-24 Y match_to: GB L12000 e-22 Y match_to: GB Z81038 e-11 W match_to: GB T21843 e-8 A EST: LD09819.3'; LD09819.5'; LD27566.5'; LD02165.5'; LD07429.5'; LD10977.5'; LD13245.5'; LD13885.5'; LD19803.5'; LD21076.5'; LD21952.5'; LD22017.5'; LD26541.5'; LD26968.5'; LD27714.5' P1: DS00929 direction: + ems_allele: l(2)35Bd¹ l(2)35Bd² l(2)35Bd³ l(2)35Bd⁴ l(2)35Bd⁵ l(2)35Bd⁶ P_element_allele: l(2)35Bd¹⁰⁴⁰⁸ sequenced aberration_associated_allele: l(2)35Bd^Ctx (Tp(3;2)Antp^Ctx) phenotypic_class: vital. SM_notes: Translation from full-length LD09819. l(2)35Bd 17448-19229 (ESTs), l(2)10408 at ~17507 (plasmid rescue). =========================================================================== \+symbol: BG:DS00929.6 \+formal_name: BG:DS00929.6 genefinder: 8/31 genscan: 684(16 spans) product: GABA receptor match_to: TR O08621 e-139 O (rat) match_to: GB Y10370 e-135 O (rat) match_to: GB W48985 e-30 M (Mus EST) match_to: GB AA036134 e-12 M (Mus EST) match_to: GB X90543 e-18 H (Hum EST) match_to: TR Q23442 e-15 W match_to: GB U58748 e-9 W EST: P1: DS00929 direction: + SM_notes: Translation from 5' and 3' edited Genscan (missing 5' end?). ========================================================================== \+symbol: BG:DS00929.7 \+formal_name: BG:DS00929.7 genefinder: genscan: product: ficolin match_to: SP P21520 e-23 D match_to: TR O18546 e-30 O (bloodfluke planorb) match_to: TR D1026054 e-28 M match_to: TR Q28763 e-27 H match_to: TR O17043 e-7 W EST: P1: DS00929 direction: - SM_notes: Translation from 3' edited BLASTX homology to GenBank P21520. ========================================================================== \+symbol: BG:DS00929.8 \+formal_name: BG:DS00929.8 genefinder: 66 genscan: 684(4 spans) product: yellow-like match_to: SP P09957 e-74 D match_to: TR O18330 e-21 O (honey bee) EST: P1: DS00929 direction: + SM_notes: Translation from 5' edited Genscan. ========================================================================== \+symbol: l(2)35Bg \+formal_name: BG:DS00929.9 synonym: anon-35Ba name: lethal (2) 35Bg UID: FBgn0001977 UID: FBgn0015867 references: FBrf0055545 == Schweisguth and Posakony, 1992, Cell 69: 1199--1212 cytology: 35B10--35B10 cytology_data: Lef