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Citation
Ashburner, M., Roote, J., Lewis, S.E., Rubin, G.M. (1999.10.12). Adh. 
FlyBase ID
FBrf0112153
Publication Type
Personal communication to FlyBase
Abstract
PubMed ID
PubMed Central ID
Text of Personal Communication
From ma11@XXXX Tue Oct 12  09:51:40  1999
Envelope-to: gm119@XXXX
Delivery-date: Tue, 12 Oct 1999  09:51:40  +0100
To: gm119@XXXX
Subject: Adh
Cc: ma11@XXXX
X-Sun-Charset: US-ASCII
From: Michael Ashburner (Genetics) <ma11@XXXX>
Date: Tue, 12 Oct 1999  09:53:33  +0100
Content-Length: 190201
Gillian
This is our working file. It can be taken as a personal communication to
FlyBase from Ashburner, Misra, Roote, Lewis & Rubin.
This version will have the new genes analysed since the paper was
submitted. These should be curated. This file is authorative over the
paper [except for the 'product' lines which were never u/dated].
Also ignore the 'cytology' & lines & refs - these were all unaltered from FB
about a year ago.
Ignore the .* suffixes on EST names.
MA
==========================================================================
Region 34-36 genes.
Michael Ashburner and John Roote and Sima Misra and Suzanna Lewis and
Gerry M. Rubin.
Version 18.1
13 Sept. 1999
\+symbol = identified on sequence
direction = direction of transcription
+ = distal to proximal
- = proximal to distal
? = unclear since only P insertion
product - often very very tentative
BLAST results: expect < e-7
GB = GenBank/dbEST TBLASTX
SP = SwissProt BLASTX
TR = trEMBL BLASTX
YPD = yeast protein database BLASTX
genefinder scores > 20
genscan scores > 45
If only part of gene prediction used, indicated number of spans.
\* = split gene prediction between 2 gene records.
Results in parentheses less than the above cutoffs.
===========================================================================
\+symbol: B4
\+formal_name:  BG:DS07660 .4
references:
Sotillos et al., 1997 Development 124: 4769-4779
cDNA_sequence: AF022364; g2636727
 pr_sequence_TREMBL:O16865 
P_element_allele:
PZ05337 sequenced
EP2503 sequenced
genefinder: 48(BACR48E02)/21(BACR48E02)
genscan: 153(BACR48E02)
product:
match_to: SP P46591 e-9 O (Candida albicans)
match_to: SP P08399 e-7 M (serine residues)
EST: LD07105.5', LD33628.5'
BAC: BACR48E02
direction: -
MA_notes: This is a divergent transcript from kuz encoding a 964 aa protein
with
no matches. 5' ends of anon-B4 and kuz a few kb apart Sotillos et al., 1997.
SM_notes: Translation from alignment to GenBank AF022364 (only 1-2314 of
4053). n(2)05337 maps to 187441 (in 4th exon), EP2503 maps to 151575 of
BACR48E02 (in 1st exon).
===========================================================================
\+symbol:  BG:BACR48E02 .1
\+formal_name:  BG:BACR48E02 .1
genefinder: 21
genscan: (31)
product:
match_to:
EST:
BAC: BACR48E02
direction: -
Nested_in: B4
SM_notes: Translation from Genefinder.
===========================================================================
\+symbol:  BG:BACR48E02 .2
\+formal_name:  BG:BACR48E02 .2
genefinder: (15)
genscan: 63
product:
match_to:
EST:
BAC: BACR48E02
direction: +
Nested_in: B4
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:BACR48E02 .3
\+formal_name:  BG:BACR48E02 .3
genefinder: 23
genscan: 54
product:
match_to:
EST:
BAC: BACR48E02
direction: +
Nested_in: B4
SM_notes: Translation from Genscan.
===========================================================================
\+symbol: kuz
\+formal_name:  BG:DS07660 .3
synonym: l(2)34Da
synonym: l(2)03782
name: kuzbanian
UID: FBgn0015954
references:
FBrf0089802 == Rooke et al., 1996, Science 273(5279): 1227--1231
FBrf0090545 == Fambrough et al., 1996, Proc. Natl. Acad. Sci. USA.
93(23): 1
3233--13238
Sotillos et al., 1997 Development 124: 4769-4779
cytology: 34C5--34C5
cytology_data: Left limit from inclusion within Df(2L)b88c75 (FBrf0092813)
cytology_data: Right limit from in situ hybridisation (FBrf0067338)
 cDNA_sequence:U60591 ; g1531633
 pr_sequence_TREMBL:Q94902 
genefinder: 23/77(BACR48E02)
genscan: 286/83(2 spans)(BACR48E02)
product: metalloprotease/disintegrin family protein
match_to: TR G2739037 (AF024614) e-128 W
match_to: TR E1246683 (Z96047) e-128 W
match_to: TR O14672 (AF009615) e-113 H
match_to: TR O35598 (AF011379) e-112 M
EST: LD04086.5', LD20268.5', LD04356.5'
BAC: BACR48E02
direction: +
TE_insert_allele:
kuz1 (TE13=TE34Cb)
kuz2 (TE60=TE34Ca)
kuz3 (TE94=TE34Cc)
P_element_allele:
kuzk01403 sequenced l(2)k01405, cluster mate ?
kuzk07601 sequenced
kuzk12004 sequenced
kuzk14817 sequenced
kuzk09934
kuzk11804
kuzk14701
l(2)0378203782 (hypomorphic allele) sequenced
rK028 sequenced
P_element_derivative_allele:
kuze29-4
kuzk01405Rev4
kuzk01405Rev11
kuzk01405Rev23
aberration_associated_allele:
kuzTE34Cc-GV2 (In(2)TE34Cc-2)
kuzTE34Cc-SV1 (In(2L)TE34Cc-1)
kuzTE34Cc-GV1 (T(2;3)TE34Cc-1)
kuzTE34Ca-GV1 (T(Y;2)TE34Ca-1)
misc_allele:
kuzIK5
kuzH143
phenotypic_class: vital.
SM_notes: Translation from alignment to GenBank U60591 (edited 3' end of
2nd exon).
rK028 maps to 151448 of BACR48E02.
===========================================================================
\+symbol:  BG:DS07660 .1
\+formal_name:  BG:DS07660 .1
genefinder: 20(BACR48E02)
genscan: 99(BACR48E02)
product: Na-dependent transporter
match_to: TR Q94886 (Y07720) e-56 D
match_to: SP Q03567 e-72 W
match_to: TR Q62634 (U07609) e-60 M
match_to: SP Q61983 e-55 M
match_to: SP Q14916 e-44 H
match_to: TR G3582333 (AC005496) e-57 A
match_to: LP07553.5' e-42 D
EST:
BAC: BACR48E02
direction: -
Nested_in: kuz
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:BACR48E02 .4
\+formal_name:  BG:BACR48E02 .4
genefinder: 42
genscan: 68
product: ras suppressor protein rsp-1
match_to: SP Q15404 e-69 H
match_to: SP Q01730 e-68 M
match_to: TR Q09497 (Z46996) e-58 W
match_to: TR E1226129 (Y16045) e-15 A
EST: LD13077.5', LD11984.5', LD18845.5', LP02171.5'
BAC: BACR48E02
direction: -
SM_notes: Translation from full-length LD13077.
===========================================================================
\+symbol:  BG:DS01368 .1
\+formal_name:  BG:DS01368 .1
genefinder: 80(DS01368)
genscan: 153(DS01368)
product:
match_to: TR Q18202 e-13 W
EST: CK00026.3', LP04233.5'
P1: DS01368
direction: +
SM_notes: Translation from full-length CK00026. CK00026.3' matches but
CK00026.5prime.contig sequence does not match; only nts 612-2123 of 2131
CK00026 full-length sequence align by sim4.
LP04233.5' looks alternatively spliced, overlaps exon 4 and 6, not 5.
===========================================================================
\+symbol:  BG:DS08249 .1
\+formal_name:  BG:DS08249 .1
genefinder: 36
genscan: 139(DS01368)/103(DS08249)
product: similar to lachesin?
match_to: SP Q26474 e-9 O (grasshopper)
EST:
P1: DS01368, DS08249, BACR48E02
direction: -
SM_notes: Translation from Genscan on DS01368. match_to: GB Z81045;g1627647
e-8 W but by 1/99 this protein in the cosmid accession no longer exists.
===========================================================================
\+symbol:  BG:DS08249 .2
\+formal_name:  BG:DS08249 .2
genefinder: 73
genscan: 163
product: mitochondrial glycerol 3-phosphate dehydrogenase
match_to: GB U12424 e-87 H
match_to: SP P43304 e-97 H
match_to: GB U60987 e-87 M
match_to: SP Q64521 e-100 M
match_to: TR E1323155 e-97 W (EMBL; Z72516)
match_to: GB Z73906 e-67 W
match_to: TR P90795 e-78 W
match_to: YPD 763191 e-61 Y
match_to: SP P32191 e-52 Y
EST:
P1: DS08249
direction: +
SM_notes: Genefinder used rather than Genscan for translation since Genscan
adds
on stuff at amino terminus.
===========================================================================
\+symbol:  BG:DS08249 .3
\+formal_name:  BG:DS08249 .3
genefinder: 50
genscan: 91
product:
match_to: TR G3342562 e-72 H (EMBL; AF077599)
match_to: GB AA305709 e-29 H (Hum EST)
match_to: GB AA212211 e-13 M (Mus EST)
match_to: LD19320.5' e-16; LD28635.5' e-16
EST:
P1: DS08249
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS08249 .4
\+formal_name:  BG:DS08249 .4
genefinder: 38
genscan: 97
product:
match_to:
EST:
P1: DS08249
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS08249 .5
\+formal_name:  BG:DS08249 .5
genefinder: (18)
genscan: 50
product:
match_to:
EST:
P1: DS08249
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS00797 .1
\+formal_name:  BG:DS00797 .1
synonym: l(2)k07245
UID: FBgn0022093
genefinder: 59
genscan: 185
product: similar to Yeast EMP70 (70kd endomembrane) gene product P24A
protein precursor
match_to: GB D87444 e-159 H (KIAA0255)
match_to: TR Q92544 e-210 H (KIAA0255)
match_to: TR Q94422 e-180 W
match_to: TR E1247604 e-180 W
match_to: TR Q12101 e-103 Y
match_to: SP P32802 e-102 Y
match_to: GB X67316 e-50 Y
match_to: GB AA272456 e-37 M (Mus EST)
match_to: GB AA117787 e-35 M (Mus EST)
match_to: TR O04091 e-73 A
match_to: GB T45159 e-24 A
EST: HL07777.5'; HL07777.3'; LD32761.5'; GH02822.5'
P_element_allele:
l(2)k07245 sequenced
P1: DS08284
direction: +
SM_notes: k07245 inserted at 7502 of DS08284, LD32671.5' is from 7511-8360,
extends further 5' than HL07777. Translation from full-length LD32761 sequence.
===========================================================================
\+symbol:  BG:DS00797 .2
\+formal_name:  BG:DS00797 .2
genefinder: 39
genscan: 77
product:
match_to: YPD 854436 e-16 Y
match_to: GB C90076 e-15 O (Dictyostelium discoideum)
EST: HL03175.5'; HL03175.3'
P1: DS08284
direction: -
SM_notes: Translation from full-length HL03175 sequence.
===========================================================================
\+symbol: p38b
\+formal_name:  BG:DS00797 .3
genefinder: 71
genscan: 173
product: MAP Kinase
match_to: GB L35253 e-115 H
match_to: GB L35264 e-115 H
match_to: SP Q16539 e-136 H
match_to: GB U10871 e-116 M
match_to: SP P47811 e-136 M
match_to: TR Q17466 e-116 W
match_to: SP P32485 e-92 Y
match_to: SP Q39026 e-86 A
EST: GM01004.3'; GM01004.5'; GM04790.5'; GM06395.5'; HL03933.5'; LD24658.5'
P1: DS08284
direction: +
SM_notes: Translation from full-length GM01004.
===========================================================================
\+symbol:  BG:DS00797 .4
\+formal_name:  BG:DS00797 .4
genefinder: 30
genscan: 69
product:
match_to: TR Q17843 e-31 W
match_to: GB Z81275 e-24 O (Scrofa EST)
match_to: GB AA114025 e-19 H (Hum EST)
match_to: GB R90322 e-16 A (Arabidopsis EST)
EST:
P1: DS08284
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS00797 .5
\+formal_name:  BG:DS00797 .5
genefinder: 87
genscan: 296
product: ABC transporter
match_to: GB X97187 e-82 H
match_to: TR Q92473 e-102 H
match_to: TR Q99758 e-102 H
match_to: GB AF000149 e-71 M
match_to: SP P41233 e-86 M
match_to: TR O01790 e-69 W
match_to: TR O22231 e-58 A
match_to: SP P55476 e-31 B
EST: CK01017.3'; CK01017.5'; LD33192.5'
P1: DS08284
direction: +
SM_notes: Translation from complete sequence of CK01017 at 5' end and
LD33192 at 3' end--neither full-length. Because homology extends 5' of
CK01017 and this library not full-length clones, gene may extend further 5'
than translation.
===========================================================================
\+symbol:  BG:DS00797 .6
\+formal_name:  BG:DS00797 .6
genefinder: 71
genscan: 170
product:
match_to: TR Q25239 e-10 O (Lucilia cuprina)
EST:
P1: DS08284
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS00797 .7
\+formal_name:  BG:DS00797 .7
genefinder: 218
genscan: 632
product: guanine nucleotide-exchange protein (SEC7)
match_to: GB J03918 e-161 Y
match_to: SP P11075 e-178 Y
match_to: TR G2674107 0.0 O (Bos taurus)
match_to: TR E1287857 e-181 A
match_to: TR Q92538 e-51 H
match_to: GB M85169 e-42 H
match_to: TR O08967 e-44 M
match_to: SP P34512 e-25 W
EST: LD10472.3'; LD10472.5'; HL01681.5'; LD29171.5'
P1: DS08284
direction: +
MA_note: Bet this is anon-34Da
SM_notes: Translation from full-length LD29171.
===========================================================================
\+symbol:  BG:DS00941 .1
\+formal_name:  BG:DS00941 .1
genefinder: 56
genscan: 122
product: carbonic anhydrase
match_to: GB U55177 e-50 O (Danio rerio)
match_to: TR G2576335 e-53 O (Danio rerio)
match_to: SP P23589 e-47 M
match_to: GB X51971 e-40 M
match_to: SP P43166 e-50 H
match_to: GB L19297 e-40 H
match_to: TR Q21614 e-28 W
match_to: GB Z68118 e-14 W
match_to: TR O04846 e-7 A
EST: GH09688.5'; GH05601.3'; GH06111.3'; GH08627.5'; GH08470.5'; GH05849.5'
P1: DS00941
direction: +
SM_notes: Translation from full-length GH09688, but problem aligning
1321-2642 (internal exon) of GH09688; GH05601.3' and GH05601.3' align
there so used these for middle of 3rd exon.
===========================================================================
\+symbol:  BG:DS00941 .2
\+formal_name:  BG:DS00941 .2
genefinder: 55
genscan: 54
product: RNA editase
match_to: GB X99383 e-23 H
match_to: GB U76420 e-23 H
match_to: SP P55265 e-18 H
match_to: TR G2981097 e-16 M
match_to: SP Q22618 e-15 W
match_to: SP P53065 e-12 Y
EST:
P1: DS00941
direction: -
SM_notes: Translation from Genscan. Missing key dsRNA binding domains.
MA_notes: Liam Keegan (Edinburgh) named it Adat and think it is a
tRNA adenosine deaminase
===========================================================================
\+symbol:  BG:DS00941 .3
\+formal_name:  BG:DS00941 .3
genefinder: 44
genscan: 99
product:
match_to: GB D76471 e-7 M (Mus EST)
match_to: TR G2772565 e-12 H (Hum EST)
EST:
P1: DS00941
direction: +
SM_notes: Translation from Genscan.
===========================================================================
symbol: l(2)34Db
name: lethal (2) 34Db
UID: FBgn0001959
references:
cytology: 34D3--34D3
cytology_data: Left limit from inclusion within Df(2L)b81a1 (FBrf0091422)
cytology_data: Right limit from complementation mapping against In(2L)tsh3
(citation unavailable)
ems_allele:
l(2)34Db1
l(2)34Db2
l(2)34Db3
l(2)34Db4
l(2)34Db5
l(2)34Db6
l(2)34Db7
l(2)34Db8
l(2)34Db9
l(2)34Db10
l(2)34Db11
l(2)34Db12
misc_allele:
l(2)34DbAS1
aberration_associated_allele:
l(2)34Dbtsh3 (In(2L)tsh3)
phenotypic_notes: escapers with rough eyes; etched wing margin; bristle
loss etc; fertile both sexes.
phenotypic_class: vital.
JR_notes: OM's in situs of DS00797 suggest that this P1 is almost entirely
distal to tsh3 break, ie that 34Db is probably either  BG:DS00941 .1, .2 or .3.
One lethal excision (out of loads of viables) from k07245 is
kuz-, 34Db+, Sos+, black+ i.e. 34Db is to the right of k07245.
===========================================================================
symbol: anon-34Da
synonym: transcript 7
references:
FBrf0057637 == Bonfini et al., 1992, Science 255: 603--606
MA_note: Bet this is  BG:DS00797 .7
===========================================================================
\+symbol: Sos
\+formal_name:  BG:DS00941 .4
name: Son of sevenless
synonym: l(2)34Ea
UID: FBgn0001965
references:
FBrf0057637 == Bonfini et al., 1992, Science 255: 603--606
FBrf0053370 == Rogge et al., 1991, Cell 64: 39--48
FBrf0053392 == Simon et al., 1991, Cell 67: 701--716
FBrf0057544 == Bowtell et al., 1992, Proc. Natl. Acad. Sci. USA. 89:
6511--6515
FBrf0057536 == Rogge et al., 1992, Proc. natn. Acad. Sci. USA. 89:
5271--5275
cytology: 34D4--34D4
cytology_data: Left limit from complementation mapping against
In(2LR)b71k1A (FBrf0091347)
cytology_data: Right limit from non-inclusion within Df(2L)b77c (citation
unavailable)
product: guanine-nucleotide-exchange-factor
motifs: PS00720 == Guanine-nucleotide dissociation stimulators CDC25 family
signature.
motifs: PS50003 == PH domain profile.
genefinder: 230
genscan: 573
match_to: TR Q07889 e-254 H
match_to: TR G303382 e-254 H
match_to: TR Q62245 e-249 M
match_to: GB L13857 e-232 H
match_to: GB Z11574 e-229 M
match_to: SP P04821 e-26 Y
match_to: TR Q22503 e-14 W
EST: GH01796.5'
P1: DS00941
direction: +
homology: species == Homo sapiens; gene == SOS2; GDB: 230041; OMIM: 601247
MEDLINE: 94102743
homology: species == Homo sapiens; gene == SOS1; GDB: 230004; OMIM: 182530
homology: species == Mus; gene == Sos1; MGD: MRK-14489
homology: species == Mus; gene == Sos2; MGD: MRK-14490
 cDNA_sequence:M83931 ; g158485
 genomic_sequence:M77501 ; g158471
 pr_sequence_PIR:A41216 
 pr_sequence_SwissProt:P26675 
ems_allele:
Sos34Ea-1
Sos34Ea-2
Sos34Ea-3
Sos34Ea-4
Sos34Ea-5
Sos34Ea-6
Sos34Ea-7
Sos34Ea-8
Sos34Ea-9
Sos34Ea-10
Sos34Ea-11
Sos34Ea-12
Sos34Ea-13
Sos34Ea-14
Sos34Ea-15
Sos34Ea-16
Sos34Ea-17
Sos34Ea-18
Sos34Ea-19
SosF1
SoseCN6
SoseCS3
SoseDN4
SoseJ2
SoseN6
P_element_allele:
E(var)3091
E(var)1891
l(2)k05224 sequenced
l(2)k06321
l(2)k05705
misc_allele:
SosJC2
SosSutor-157
SosSutor-405
Sose0D
Sose1A
Sose2H
Sose4G
Sose6C
Sosex63
Sosx122
Sosx15
phenotypic_class: vital.
phenotypic_notes: escapers with small rough eyes; wing vein gaps.
SM_notes: Translation from alignment of GenBank M83931.
===========================================================================
\+symbol: b
\+formal_name:  BG:DS00941 .5
name: black
synonym: Gad2
synonym: anon-34Db
synonym: transcript 1 Bonfini
UID: FBgn0000153
UID: FBgn0005622
references:
FBrf0064653 == Phillips et al., 1993, J. Neurochem. Suppl. 61(4):
1291--1301
FBrf0082478 == Phillips et al., 1995, Abstr. Europ. Symp. Dros.
Neurobiol. 5: 44--45
FBrf0053317 == Phillips et al., 1991, Greenspan, Palka, 1991: 97
cytology: 34D6--34D6
cytology_data: Left limit from complementation mapping against
T(2;3)b79b6 (citation unavailable)
cytology_data: Right limit from complementation mapping against
T(2;3)b79b6 (citation unavailable)
enzyme: glutamate decarboxylase == EC 4.1.1.15
 cDNA_sequence:U01239 ; g402252
 pr_sequence_TREMBL:Q24062 
 pr_sequence_PIR:JH0827 
genefinder: 109
genscan: 259
match_to: GB X69936 e-109 H
match_to: SP Q05329 e-115 H
match_to: TR Q64611 e-127 O (Rattus norvegicus)
match_to: TR O35119 e-114 M
match_to: SP P48320 e-114 M
match_to: GB L16980 e-110 M
match_to: GB Z14925 e-14 W
EST: HL08051.5'; HL07852.5'
P1: DS00941
direction: +
spontaneous_allele:
b1
b14b28
b18c27
b23b2
b24b15
b29
b34g
b39
b39j
b40c
b82c1
UV_allele:
b50d
b51f
gamma_ray_allele:
b661
b71k2
b75a
b76e1
b76e2
b76f3
b77j
b78a
b79b1
b79d2
b79df2
b79dt3
b79g2
b79h2
b79h3
b80c1
b80i2
b80i3
b80j1
b80j2
b80k1
b80k2
b80l1
b80l2
b81a2
b81c17
b81c2
b81f2
b81h2
b81k
b81l2
b81l40
b81l42
b83b1
b83b40
b83c20
b83c25
b83c26
b83c35a
b83c35b
b83c36
b83c47
b83f17
b83f18
b83f51
b83f52
b84b1
b84h70
b85b3
b85b4
caffeine/gamma_ray_allele:
b74b2
b74b4
b74b5
b74c2
b74c4
b74c5
b74d2
b74d4
b74d6
b76b1
b76b2
actinomycin_D/gamma_ray_allele:
b76j1
b76j2
b76j3
b76k1
b76k2
b77a1
b77a2
b77a3
b77a4
b77a5
NaF/gamma_ray_allele:
b78f1
b78f2
b78g
b78k1
b78k2
b78k3
b78k4
b78k5
neutrons/gamma_ray_allele:
b79d6
b79d8
b79dt0
X_ray_allele:
b77.1X
b77.2X
b77.5X
b83fXD
b84g
b84h34
b84h40
neutron_allele:
b79a1
b79a2
b79a3
b79b7
b79d4
b79dt1
b81c
b82c16
b82c3
b82c54
b82c7
b83d29b
b83d35
b83d36
b83l
b85c3
ems_allele:
b75f
b77.3e
b77.4e
bA
bA51
bA53
bA54
bA55
diepoxyoctane_allele:
b78.1
misc_allele:
b66h
b81dt
P_element_allele:
bP
aberration_associated_allele:
b36f (Tp(2;3)dp)
b79b6 (T(2;3)b79b6)
b79d5 (In(2L)b79d5)
b79d6 (T(2;3)b79d6)
b79h1 (Tp(2;2)b79h1)
b80c2 (In(2L)b80c2)
b81a (In(2LR)b81a2)
b81f1 (Df(2L)b81f1)
b81f3 (In(2L)b81f3)
b81l17 (In(2L)b81l7)
b82c44 (In(2L)b82c44)
b83b2 (In(2L)b83b22)
b85c2 (T(2;3)b85c2)
phenotypic_notes: black body color; puparial case light; lacks
beta-alanine; presumably on beta-alanine pathway.
phenotypic_class: visible; non_vital.
misc_note: if GAD acts as an aspartate decarboxylase then b = Gad2.
JR_notes: Marie Phillips (Melbourne) wrote (1991) that Gad2 was in
Df(2L)b84a4 but not in Df(2L)b84a8.
SM_notes: Translation from alignment of GenBank U01239.
===========================================================================
\+symbol: tamas
\+formal_name:  BG:DS00941 .6
name: lethal (2) 34Dc
synonym: DNApol-γ125
synonym: l(2)34Dc
synonym: anon-34Dc
synonym: transcript 2 Bonfini
UID: FBgn0001960
UID: FBgn0004406
references:
FBrf0090361 == Lewis et al., 1996, J. Biol. Chem. 271(38): 23389--23394
FBrf0092749 == Ropp and Copeland, 1996, Genomics 36(3): 449--458
FBrf0089488 == Ropp, 1996.9.23, personal communication
FBrf0056420 == Olson and Kaguni, 1992, J. Biol. Chem. 267: 23136--23142
FBrf0050857 == Kaguni and Olson, 1989, Proc. natn. Acad. Sci. USA.
86(17): 6469--6473
FBrf0047578 == Wernette et al., 1988, Biochemistry 27: 6046--6054
FBrf0044677 == Wernette and Kaguni, 1986, J. Biol. Chem. 261(31):
14764--14770
FBrf0063558 == Kaguni et al., 1988, Cancer Cells 6: 425--432
FBrf0064748 == Williams et al., 1993, J. Biol. Chem. 268(33): 24855--24862
FBrf0079622 == Williams and Kaguni, 1995, J. Biol. Chem. 270(2): 860--865
FBrf0085690 == Olson et al., 1995, J. Biol. Chem. 270(48): 28932--28937
FBrf0090538 == Dusenbery and Smith, 1996, Mutat. Res. 364(3): 133--145
cytology: 34D6--34D8
cytology_data: Left limit from complementation mapping against
In(2L)b79d5 (citation unavailable)
cytology_data: Right limit from inclusion within Df(2L)b82a3 (citation
unavailable)
enzyme: mitochondrial DNA-directed DNA polymerase, catalytic subunit == EC
2.7.7.7
genefinder: 143
genscan: 337
match_to: TR Q92515 e-232 H
match_to: GB U60325 e-215 H
match_to: GB X98093 e-215 H
match_to: SP P54099 e-216 M
match_to: GB U53584 e-203 M
match_to: SP P15801 e-129 Y
match_to: GB Z75238 e-104 Y
match_to: GB D35928 e-10 W
EST: LD06421.5'; LD18609.5'; LD02053.5'
P1: DS00941
direction: -
 genomic_sequence:U60298 ; g1401344
 cDNA_sequence:U62547 ; g1552493
 pr_sequence_SwissProt:Q27607 
 pr_sequence_TREMBL:Q94906 
ems_allele:
l(2)34Dc1
l(2)34Dc2
l(2)34Dc3
l(2)34Dc4
l(2)34Dc5
l(2)34Dc6
l(2)34Dc7
l(2)34Dc8
phenotypic_class: vital.
JR_notes: Ann Regina Campos (Ontario) picked up as mutation in adult/larval
visual system; B. Iyengar <iyengabg@XXXX>
SM_notes: Translation from alignment of GenBank U62547.
===========================================================================
\+symbol: Sop2
\+formal_name:  BG:DS00941 .7
name: Suppressor of profilin
synonym: l(2)34Dd
UID: FBgn0001961
references:
<camposa@XXXX> to JR 13 March 1997.
cytology: 34D6--34D8
cytology_data: Left limit from complementation mapping against In(2L)b79h1A
(citation unavailable)
cytology_data: Right limit from inclusion within Df(2L)b82a3 (citation
unavailable)
homology: species == S. pombe; gene == sop2 EMBO J. 15: 6426
genefinder: 75
genscan: 199
match_to: TR Q92747 e-106 H
match_to: GB Y08999 e-102 H
match_to: GB Z36103 e-59 Y
match_to: SP P38328 e-60 Y
match_to: GB W08597 e-49 M (Mus EST)
match_to: GB AA408535 e-49 M (Mus EST)
match_to: GB C12211 e-36 W
EST: CK00388.3'
P1: DS00941
direction: -
ems_allele:
l(2)34Dd1
l(2)34Dd2
l(2)34Dd3
phenotypic_notes: interallelic escapers.
phenotypic_class: vital.
JR_notes: Information on product & orders from Andrew Hudson (chez Cooley).
SM_notes: Translation from alignment of cDNA from A. Hudson (from GM library).
===========================================================================
\+symbol: Orc5
\+formal_name:  BG:DS00941 .8
name: Origin recognition complex subunit 5
synonym: l(2)34Df
UID: FBgn0001963
references:
FBrf0085120 == Gossen et al., 1995, Science 270(5242): 1674--1677
FBrf0086393 == Ehrenhofer-Murray et al., 1995, Science 270(5242):
1671--1674
cytology: 34D6--34E2
cytology_data: Left limit from non-inclusion within Df(2L)b88b42 (citation
unavailable)
cytology_data: Right limit from inclusion within Df(2L)b83l1 (citation
unavailable)
product: origin recognition complex subunit
genefinder: 59
genscan: 166
match_to: TR G2906228 e-58 H
match_to: TR G2739446 e-58 H
EST:
P1: DS00941
direction: +
 cDNA_sequence:U43505 ; g1136136
 pr_sequence_SwissProt:Q24169 
ems_allele:
l(2)34Df1
l(2)34Df2
phenotypic_class: vital.
JR_notes: Information on Orc5 from Michelle Pflumme (chez Mike Botchan).
SM_notes: Translation from alignment of GenBank U43505.
===========================================================================
\+symbol: MtPolB
\+formal_name:  BG:DS00941 .9
synonym: l(2)34De
UID: FBgn0020398
UID: FBgn0001962
cytology: 34D8--34E1
cytology_data: Left limit from non-inclusion within Df(2L)b85b2 (citation
unavailable)
cytology_data: Right limit from non-inclusion within Df(2L)A47 (FBrf0038050)
references:
FBrf0093778 == Wang et al., 1997, J. Biol. Chem. 272(21): 13640--13646
 cDNA_sequence:U94702 ; g2114434
 pr_sequence_TREMBL:O02005 
enzyme: mitochondrial DNA-directed DNA polymerase, accessory subunit == EC
2.7.7.7
genefinder: 25/26
genscan: 86
match_to: SP P54098 e-231 H
match_to: TR Q92515 e-232 H
EST: GM03048.3'; GM03048.5'
P1: DS00941
direction: -
ems_allele:
l(2)34De1
l(2)34De2
l(2)34De3
phenotypic_class: vital.
JR_notes: Identity of 34De and MtPolB based on mapping with b89e12 ordering
34De and 34Dg.
SM_notes: Translation from alignment of GenBank U94702.
===========================================================================
\+symbol: RpII33
\+formal_name:  BG:DS00941 .10
name: lethal (2) 34Dg
synonym: l(2)34Dg
UID: FBgn0001964
references:
cytology: 34D8--34D8
cytology_data: Left limit from non-inclusion within Df(2L)b85b2 (citation
unavailable)
cytology_data: Right limit from inclusion within Df(2L)b81l42 (citation
unavailable)
product: RNA polymerase II 33 KD subunit
enzyme: DNA-directed RNA polymerase == EC 2.7.7.6
genefinder: 53
genscan: 161
match_to: GB AF008443 e-105 H
match_to: TR O15161 e-107 H
match_to: SP P19387 e-106 H
match_to: GB D83999 e-100 M
match_to: SP P97760 e-101 M
match_to: TR Q93338 e-82 W
match_to: GB Z81079 e-41 W
match_to: GB M27496 e-53 Y
match_to: SP P16370 e-56 Y
match_to: TR Q39211 e-45 A
EST: LD09978.3'; LD09978.5'; LD05121.5'; LD08178.5'
P1: DS00941
direction: +
ems_allele:
l(2)34Dg1
l(2)34Dg2
P_element_allele:
l(2)k05605 sequenced
phenotypic_class: vital.
JR_notes: Information on product & orders from Andrew Hudson (chez Cooley).
SM_notes: Translation from full-length LD09978.
===========================================================================
\+symbol:  BG:DS00941 .11
\+formal_name:  BG:DS00941 .11
genefinder: 47
genscan: 98
product:
match_to:
EST:
P1: DS00941
direction: -
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS00941 .12
\+formal_name:  BG:DS00941 .12
genefinder: 58
genscan: 139
product:
match_to:
EST:
P1: DS00941
direction: -
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS00941 .13
\+formal_name:  BG:DS00941 .13
genefinder: 50
genscan: 113
product:
match_to:
EST: LP05416.5'
P1: DS00941
direction: +
SM_notes: Translation from full-length LP05416.
==========================================================================
\+symbol:  BG:DS00941 .14
\+formal_name:  BG:DS00941 .14
genefinder: 65
genscan: 145
product:
match_to:
EST: LP05733.5', LP01570.5', LP03350.5'
P1: DS00941
direction: +
SM_notes: Translation from full-length LP05733.
==========================================================================
\+symbol:  BG:DS00941 .15
\+formal_name:  BG:DS00941 .15
genefinder: 32
genscan: (43)
product:
match_to:
EST: LP04791.5'
P1: DS00941
direction: +
SM_notes: Translation from LP04791.5' at 5' end and Genscan at 3' end.
==========================================================================
\+symbol:  BG:DS08220 .1
\+formal_name:  BG:DS08220 .1
P_element_allele:
PZ06646 sequenced
rN149 sequenced
ms(2)k10802 sequenced not male-sterile
genefinder: 127(DS08220)
genscan: (22)(DS00941)/298(DS08220)
product:
match_to: GB D79989 e-103 H (KIAA0167)
match_to: TR O00578 e-114 H
match_to: GB C08626 e-16 W (worm EST)
match_to: GB C08427 e-14 W (worm EST)
match_to: TR O04097 e-11 A
match_to: GB T04032 e-9 A
EST: LD11783.5'; LD11783.3'; GM01069.5'; GM01069.3'
P1: DS00941, DS08220
direction: +
JR_notes: all excisions of 06646 viable; 2/44 excisions of rN149 are lethal
but lethality not to this region (being mapped by JR).
SM_notes: Translation from full-length LD11783. n(2)rN149 and PZ06646 map
to ex
actly the same nucleotide with the
same orientation, 4552 of DS00941 (d>p revcomp 76272 of DS00941);
ms(2)k10802 maps at 3710 of DS00941.
LD11783.5' is from 3699-3125 (d>p revcomp 77325-77899), 1kb downstream of
rN149/PZ06646, and 11bp downstream of ms(2)k10802.
==========================================================================
\+symbol: anon-34Ea
\+formal_name:  BG:DS08220 .2
references:
FBrf0083469 == Tatei et al., 1995, Mech. Dev. 51(2-3): 157--168
P_element_allele:
EP(2)2171 sequenced
genefinder: 175
genscan: 505
product:
match_to:
EST: LD02558.3'; LD02558.5'; LD06162.3'; LD06162.5'; LD20278.5';
LD12350.5'; LD22235.5'; LD29084.5'
P1: DS08220
direction: -
misc_data: 16.5kb EcoRI fragment including the Ance and anon-34Ea genes.
SM_notes: Translation from full-length LD02558. EP(2)2171 is inserted at
3159 of DS08220, LD29084.5' first exon
is 3139-3164, so P is 5bp upstream of first intron.
===========================================================================
\+symbol: Ance
\+formal_name:  BG:DS08220 .3
synonym: l(2)34Eb
name: Angiotensin converting enzyme
UID: FBgn0012037
references:
FBrf0081664 == Cornell et al., 1995, J. Biol. Chem. 270(23): 13613--13619
FBrf0083469 == Tatei et al., 1995, Mech. Dev. 51(2-3): 157--168
FBrf0087131 == Frank and Rushlow, 1996, Development 122(5): 1343--1352
FBrf0090455 == Biehs et al., 1996, Genes Dev. 10(22): 2922--2934
FBrf0092672 == Rusch and Levine, 1997, Development 124(2): 303--311
cytology: 34E2--34E2+
cytology_data: Left limit from inclusion within Df(2L)Adh-nBR55 (FBrf0083469)
cytology_data: Right limit from inclusion within Df(2L)b74c6 (citation
unavailable)
enzyme: peptidyl-dipeptidase A == EC 3.4.15.1
homology: species == Mus; gene == Ace; MGD: MRK-1032
homology: species == Homo sapiens; gene == DCP1; GDB: 119840; OMIM: 106180
genefinder: 41(DS08220)/107(DS00180)
genscan: 114(DS08220)/296*(DS00180)
match_to: SP Q10715 e-71(DS08220)/e-208(DS00180) O (Haematobia irritans)
match_to: GB L43965 e-66(DS08220)/e-206(DS00180) O (Haematobia irritans)
match_to: SP P22966 e-16(DS08220)/e-101(DS00180) H
match_to: GB M26657 e-13(DS08220)/e-99(DS00180) H
match_to: GB A31567 e-13(DS08220)/e-99(DS00180) H
match_to: GB X16295 e-13(DS08220)/e-99(DS00180) H
match_to: GB J04144 e-13(DS08220)/e-173(DS00180) H
match_to: GB A00914 e-13(DS08220)/e-173(DS00180) H
match_to: SP P22967 e-16(DS08220)/e-106(DS00180) M
match_to: SP P09470 e-190(DS00180) M
match_to: GB M55333 e-14(DS08220)/e-104(DS00180) M
match_to: GB J04946 e-151(DS00180) M
match_to: TR Q18581 e-26(DS00180) W
EST: LD11258.5'; LD11258.3'; LD06090.5'; LD17344.5'; GM02190.5'; GM01822.5'
P1: DS08220, DS00180
direction: +
 cDNA_sequence:U25344 ; g1373009
 cDNA_sequence:U34599 ; g1002909
 pr_sequence_SwissProt:Q10714 
 pr_sequence_PIR:A57533 
ems_allele:
Ance34Eb-1
Ance34Eb-2
phenotypic_class: vital.
SM_notes: Translation of 3' from aligned GenBank U25344 on DS00180.
===========================================================================
symbol: l(2)34Ec
JR_notes: predicted by non rescue by Ance transgene of some Ance- o/laps.
===========================================================================
\+symbol: Acyp
\+formal_name:  BG:DS00180 .1
UID: FBgn0025115
references:
\*x FBrf0104497 == Pieri et al., 1998, FEBS Lett. 433(3): 205--210
enzyme: acyl phosphatase == EC 3.6.1.7
genefinder: 20
genscan: 296* (one span)
match_to: SP P56375 e-15 M
match_to: SP P07311 e-15 H
match_to: GB X84194 e-13 H
match_to: GB X84195 e-13 H
match_to: GB AA285985 e-13 M (mus EST)
EST:
P1: DS00180
direction: +
 pr_sequence_SwissProt:P56544 
SM_notes: Translation from Genefinder.
==========================================================================
\+symbol:  BG:DS00180 .2
\+formal_name:  BG:DS00180 .2
genefinder: 69
genscan: 184
product:
match_to: TR Q39721 e-49 O (Euglena gracilis)
match_to: TR Q22807 e-9 W
EST:
P1: DS00180
direction: -
SM_notes: Translation from Genefinder.
==========================================================================
\+symbol:  BG:DS00180 .3
\+formal_name:  BG:DS00180 .3
genefinder: 66
genscan: 142/145(2 spans)
product: articulin
match_to: TR Q39721 e-49 O (Euglena gracilis)
match_to: SP Q02817 e-21 H
match_to: YPD 763364 e-19 Y
match_to: SP P15265 e-8 M
EST: HL02234.5'; HL02234.3'
P1: DS00180
direction: -
SM_notes: Translation from full-length HL02234.
==========================================================================
\+symbol:  BG:DS00180 .5
\+formal_name:  BG:DS00180 .5
genefinder: 23/35
genscan: 201*(9 spans)
product:
match_to: SP Q10715 e-203 O
match_to: SP P09470 e-190 M
match_to: SP P12821 e-187 H
match_to: TR Q18581 e-8 W
EST:
P1: DS00180
direction: +
SM_notes: Translation from edited Genscan.
==========================================================================
\+symbol:  BG:DS00180 .12
\+formal_name:  BG:DS00180 .12
genefinder: 32*(3 spans)
genscan: 201*(3 spans)
product:
match_to: SP Q61554 e-43 M
match_to: SP P35555 e-41 H
match_to: TR Q23587 e-22 W
EST: GH08194.5'; GH07762.5'
P1: DS00180
direction: +
SM_notes: Translation from full-length GH07762.
==========================================================================
\+symbol:  BG:DS00180 .7
\+formal_name:  BG:DS00180 .7
genefinder: 67
genscan: 100
product: tenascin X-like repeat
match_to: SP P24821 e-30 H
match_to: TR Q08424 e-44 H
match_to: TR O35452 e-43 M
match_to: SP P98133 e-37 O (cow)
match_to: SP P14585 e-13 W
match_to: TR O18375 e-29 D
EST: HL01444.5'; HL01444.3'
P1: DS00180
direction: -
SM_notes: Translation from full-length HL01444
===========================================================================
\+symbol:  BG:DS00180 .8
\+formal_name:  BG:DS00180 .8
genefinder: 62
genscan: 128
product: tenascin-like repeat
match_to: SP P24821 e-30 H
match_to: TR Q08424 e-44 H
match_to: TR O18375 e-29 D
match_to: TR Q64706 e-26 M
match_to: TR O01343 e-16 W
EST: CK00536.5'; CK00194.5'
P1: DS00180
direction: -
SM_notes: Translation from full-length CK00536.
===========================================================================
\+symbol:  BG:DS00180 .9
\+formal_name:  BG:DS00180 .9
genefinder: 30
genscan: 85
product: tenascin/Notch-like repeat
match_to: SP P10039 e-31 O (chicken)
match_to: TR D1013803 e-15 H
match_to: SP Q61554 e-31 M
EST:
P1: DS00180
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS00180 .10
\+formal_name:  BG:DS00180 .10
genefinder: 21
genscan: 120
product: Notch-like repeat
match_to: SP Q01705 e-26 M
match_to: TR Q23587 e-24 W
match_to: TR O18375 e-29 D
match_to: HL01967.5' D (Dros EST)
EST: LP05465.5'
P1: DS00180
direction: -
SM_notes: Translation from 5'EST and Genscan.
==========================================================================
\+symbol:  BG:DS00180 .11
\+formal_name:  BG:DS00180 .11
genefinder: 91*(5 spans)
genscan: 217*(6 spans)
product: cytochrome P450
match_to: TR G2673981 e-153 O (D.mettleri)
match_to: TR Q64407 e-18 M
match_to: SP P33268 e-16 H
match_to: HL05525.5' D (Dros EST)
EST:
P1: DS00180
direction: +
SM_notes: Translation from edited Genscan. Cyp28a5 67% identical to Cyp28a1
==========================================================================
\+symbol:  BG:DS00180 .14
\+formal_name:  BG:DS00180 .14
genefinder: 91*(2 spans)
genscan: 217*(3 spans)
match_to: TR Q15567 e-32 H
match_to: TR O18375 e-32 D
EST:
P1: DS00180
direction: +
SM_notes: Translation from edited Genscan.
==========================================================================
symbol: j
name: jaunty
UID: FBgn0001277
references:
cytology: 34E3--34E3
cytology_data: Left limit from inclusion within Df(2L)fn26 (FBrf0030161)
cytology_data: Right limit from non-inclusion within Df(2L)A376 (FBrf0038050)
spontaneous_allele:
j2
j49j
j50e
j58i
ems_allele:
j63
jSF7
misc_allele:
j1
phenotypic_notes: wings upturned.
phenotypic_class: visible; non_vital.
===========================================================================
\+symbol: rk
\+formal_name:  BG:DS00180 .13
name: rickets
UID: FBgn0003255
references:
cytology: 34E4--34E5
cytology_data: Left limit from inclusion within Df(2L)fn12 (FBrf0030161)
cytology_data: Right limit from inclusion within Df(2L)b-L (FBrf0036112)
genefinder: 87/12(DS00180)/26(DS01514)
genscan: 207(DS00180)/59(DS01514)
product: lutropin/choriogonadotropin receptor
match_to: TR U47005 e-77(DS00180) D
match_to: TR Q94979 e-77(DS00180) D
match_to: GB M73746 e-79(DS00180) H
match_to: GB M63108 e-79(DS00180) H
match_to: SP P22888 e-82(DS00180) H
match_to: SP P30730 e-82(DS00180) M
match_to: GB M81310 e-77(DS00180) M
match_to: TR Q18759 e-41(DS00180) W
match_to: GB Z73971 e-19(DS00180) W
match_to: TR O15421 e-9(DS01514) H
EST:
P1: DS00180, DS01514
direction: -
spontaneous_allele:
rk4
rk5
rkcyl
X_ray_allele:
rk6
gamma_ray_allele:
rk81f2
rk84b1
UV_allele:
rk1
rk2
rk3
ems_allele:
rk1250
rk76
rk80l1
rk80l2
rkEMS
PM_dysgenesis_allele:
rkKe1
P_element_allele:
rk11P sequenced
misc_allele:
rkAS3
rkIK6
aberration_associated_allele:
rknoc11 (Df(2L)noc11)
phenotypic_notes: legs 'crippled'; tarsal segements short etc.
phenotypic_class: visible; non_vital.
JR_notes: James Baker (chez Jim Truman) suspects rk to be involved in
control of eclosion behaviour by peptide hormones.
SM_notes: Translation 5' from Genscan on DS01514, 3' from Genscan on
DS00180. rk11P maps to 9522 of DS01514, sequence from Baker is from
5576-1.
===========================================================================
\+symbol:  BG:DS01514 .3
\+formal_name:  BG:DS01514 .3
genefinder:
genscan: 49
product:
match_to:
EST:
P1: DS01514
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS01514 .1
\+formal_name:  BG:DS01514 .1
genefinder:
genscan:
tRNAscan-SE: 69
product: transfer  RNA:gln 
match_to: GB X68534 e-5 O (rat)
EST:
P1: DS01514
direction: -
Nested_in:  BG:DS01514 .3
==========================================================================
\+symbol:  BG:DS01514 .2
\+formal_name:  BG:DS01514 .2
synonym: 2a9hom
P_element_allele:
k09909 sequenced
genefinder: 93(DS01514)/93(DS00131)
genscan: 210(DS01514)/230(DS00131)
product: long chain fatty acid CoA-ligase
match_to: SP Q10776 e-35(DS01514)/e-42(DS00131) B (Mycobacterium tuberculosis)
match_to: TR O30039 e-34(DS01514)/e-40(DS00131) B (Archaeoglobus fulgidus)
match_to: GB Z74020 e-22(DS01514)/e-37(DS00131) B (Mycobacterium tuberculosis)
match_to: SP P33121 e-28(DS01514)/e-31(DS00131) H
match_to: GB D10040 e-23(DS01514)/e-29(DS00131) H
match_to: SP P41216 e-27(DS01514)/e-32(DS00131) M
match_to: GB U15977 e-31(DS00131) M
match_to: TR Q18660 e-20(DS01514)/e-21(DS00131) W
match_to: TR Q20264 e-16(DS01514) W
match_to: TR G2736373 e-24(DS00131) W
match_to: SP P30624 e-23(DS01514) Y
match_to: SP P39518 e-23(DS00131) Y
match_to: TR O22898 e-25(DS01514)/e-25(DS00131) A
EST: LD10778.5'; LD10778.3'; LD02830.5'; HL05723.5'; GM08372.5';
GM14009.5'; GH01357.5'; GH02862.5'; GH02258.5'
P1: DS01514, DS00131
direction: +
SM_notes: Translation from aligned cDNA sequence from M. Leptin (expressed
in anterior mesoderm, later in hemocytes) on DS01514 (5') and DS00131 (3').
==========================================================================
\+symbol: l(2)34Fa
\+formal_name:  BG:DS05899 .2
name: lethal (2) 34Fa
UID: FBgn0001967
cytology: 34F2+--34F2+
cytology_data: Left limit from inclusion within Df(2L)Adh-nBR41 (FBrf0091422)
cytology_data: Right limit from inclusion within Df(2L)b88f43 (FBrf0092813)
genefinder: 37(DS00131)/37(DS05899)
genscan: 84(DS00131)/57(DS05899)
product:
match_to:
EST:
P1: DS00131, DS05899
direction: -
ems_allele:
l(2)34Fa1
l(2)34FaCH59
P_element_allele:
l(2)34Fak00811 sequenced
EP(2)2418 sequenced
aberration_allele: Df(2L)el20 (hypomorphic)
phenotypic_class: vital.
SM_notes: Translation from Genscan prediction on DS00131.
===========================================================================
\+symbol:  BG:DS05899 .1
\+formal_name:  BG:DS05899 .1
synonym: 2a9
genefinder: 87
genscan: 252
product: long chain fatty acid CoA-ligase
match_to: GB AL021957 e-46 O (Mycobacterium tuberculosis)
match_to: TR E1253260 e-54 O (Mycobacterium tuberculosis)
match_to: TR D1032567 e-108 H
match_to: SP P41215 e-25 H
match_to: SP P41216 e-24 M
match_to: TR Q19339 e-19 W
match_to: SP P39518 e-16 Y
match_to: TR O23268 e-28 A
EST: LD28132.5'
P1: DS05899
direction: +
SM_notes: Translation from aligned cDNA sequence from M. Leptin (expressed
in mesoderm and later in fatbody).
===========================================================================
\+symbol:  BG:DS05899 .7
\+formal_name:  BG:DS05899 .7
genefinder:
genscan: 55
product: repeated Leucine-rich segment found in many proteins
match_to: TR Q18902 e-27 W
match_to: SP P35858 e-21 H
match_to: SP P70389 e-21 M
match_to: SP P36047 e-14 Y
EST:
P1: DS05899
direction: -
SM_notes: Translation from Genscan prediction.
==========================================================================
\+symbol:  BG:DS05899 .6
\+formal_name:  BG:DS05899 .6
genefinder:
genscan: 46
product:
match_to:
EST:
P1: DS05899
direction: -
SM_notes: Translation from Genscan prediction.
===========================================================================
\+symbol:  BG:DS05899 .3
\+formal_name:  BG:DS05899 .3
genefinder: 42
genscan: 106
product:
match_to: SP Q61554 e-8 M (fibrillin precursor)
match_to: SP P41990 e-7 W (Apx-1 precursor)
EST:
P1: DS05899
direction: +
SM_notes: Translation from Genscan prediction.
===========================================================================
\+symbol:  BG:DS05899 .5
\+formal_name:  BG:DS05899 .5
genefinder:
genscan: 94
product:
match_to: GB L42311 e-12 D (shn)
match_to: GB U42403 e-10 D (sr)
EST:
P1: DS05899
direction: +
SM_notes: Translation from Genscan prediction.
==========================================================================
\+symbol:  BG:DS05899 .4
\+formal_name:  BG:DS05899 .4
genefinder: (14)
genscan: 64
product: neuronal acetylcholine receptor, α-7 chain precursor
match_to: TR E1246208 e-102 H
match_to: SP P36544 e-103 H
match_to: SP P49582 e-104 M
match_to: GB L37663 e-75 M
match_to: SP P48180 e-99 W
match_to: GB X83887 e-73 W
match_to: SP P09478 e-62 D
match_to: HL02253.5' D (Dros EST)
EST:
P1: DS05899
direction: +
SM_notes: Translation from edited Genscan. Not DopR. Region 6.5kb
upstream and 2 regions downstream with good homology to receptor but no
start codon (stop codon just after nearest M). Removed last 2 exons of
Genscan prediction (low prob.) and used for translation.
===========================================================================
\+symbol:  BG:DS01759 .1
\+formal_name:  BG:DS01759 .1
genefinder: 77
genscan: 192
product: proline-rich region like mucin
match_to: TR Q29071 e-11 O (pig)
match_to: SP Q02817 e-9 H
match_to: SP P37370 e-7 Y
EST:
P1: DS01759
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS01759 .2
\+formal_name:  BG:DS01759 .2
genefinder: (14)
genscan: 45
product:
match_to:
EST: HL03474.5'
P1: DS01759
direction: -
SM_notes: Translation from full-length HL03474.
==========================================================================
\+symbol:  BG:DS01523 .1
\+formal_name:  BG:DS01523 .1
genefinder: 112
genscan: 230
product:
match_to: GB W26043 e-18 H (Hum EST)
EST:
P1: DS01523
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS01523 .2
\+formal_name:  BG:DS01523 .2
genefinder: 153
genscan: 510
product: repeated segment found in mucin
match_to: SP Q02817 e-65 H
match_to: TR Q61002 e-21 M
match_to: TR O17893 e-51 W
match_to: SP P08640 e-46 Y
match_to: TR O23054 e-28 A
match_to: GB D49534 e-12 D (cno)
match_to: LD02410.5'
e-6;LD17667.5';LD12158.5';LD34053.5';GM09485.5';LD033260.5';LD23668.5' D
(Dros EST)
EST:
P1: DS01523
direction: -
SM_notes: Translation from Genscan.
==========================================================================
\+symbol: smi35A
\+formal_name:  BG:DS01523 .3
genefinder: 48/33
genscan: 217
product: Dyrk2 kinase
match_to: TR Q92630 e-81 H
match_to: SP Q13627 e-48 H
match_to: TR Q61214 e-48 M
match_to: GB U58497 e-28 M
match_to: TR Q20604 e-61 W
match_to: SP P14680 e-33 Y
EST: CK02015.5'; LD10161.5'; LD10161.3'; LD20817.5'; LD20817.3';
HL01379.5'; HL01379.3'; GM04027.5'; LD02884.5'; LD15788.5'; LD33744.5'
P1: DS01523, DS01652, DS03792
direction: -
P_element_allele:
rff(2)k11509 sequenced
smi35A1 sequenced by Anholt
rff(2)k06901 sequenced
SM_notes: Translation from full-length LD10161 on DS01523 edited
(542-3970), DS01652 (426-541), DS03792 (1-425). k11509 maps to 82600 of
DS03792 (first exon),
k16716 maps to 53181, smi35A to 53174, and k06901 to 53160 of DS03792.
===========================================================================
\+symbol: wb
\+formal_name:  BG:DS03792 .1
synonym: l(2)34Fb
name: wing blister
UID: FBgn0004002
references:
FBrf0046354 == Hilliker and Trusis-Coulter, 1987, Genetics 117: 233--244
cytology: 34F5--34F5
cytology_data: Left limit from inclusion within Df(2L)TE35B-10 (FBrf0091422)
cytology_data: Right limit from inclusion within Df(2L)b78j (citation
unavailable)
genefinder: (14)/(16)/79(DS03792);68/150(DS01068)
genscan: 337/(41)(DS03792);565(DS01068)
product: laminin-α2 subunit (merosin)
match_to: SP P24043 e-128(DS01068) H laminin-α2
match_to: GB X58531 e-112(DS03792) H laminin-α1
match_to: SP P25391 e-112(DS03792)/e-125(DS01068) H laminin-α1
match_to: SP Q60675 e-128(DS01068) M laminin-α2
match_to: GB J04064 e-114(DS03792) M laminin-α1
match_to: SP P19137 e-114(DS03792)/e-122(DS01068) M laminin-α1
match_to: TR E1247268 e-122(DS03792) W laminin-like
match_to: SP Q21313 e-95(DS01068) W laminin-like
match_to: SP Q00174 e-104(DS01068) D laminin-α
EST: CK00390.5'; CK02229.5'; CK02229.3'; CK01592.3'
P1: DS03792, DS01068
direction: +
cDNA_sequence: AF135118.1
ems_allele:
wb1
wb3
wb4
wb91g2
wbBMW22
wbBMW32
wbCH18
wbCH20
wbCH38
wbCH41
wbCH57
wbCH67
wbCH70
wbCR1
wbDM10
wbGM2
wbHG10
wbHG14
wbHG16
wbHG17
wbHG18
wbHG19
wbHG24
wbHG26
wbHG7
wbHG9
wbL412
wbOK14
wbPA43
wbSF19A
wbSF20
wbSF25
tem_allele:
wbSF11
P_element_allele:
wb09437 sequenced Baumgartner
wb10002 sequenced Baumgartner
wbk06511 cluster: k06520
wbk08909
wbk14208
wbk05612
wbk00805
wbk13507
wbH155 sequenced Baumgartner
rL918 sequenced
n(2)k16716 sequenced
PM_dysgenesis_allele:
wbPI5
X_ray_allele:
wbSF30
gamma_ray_allele:
wbGR301
aberration_associated_allele:
wb6r28 (T(2;3)6r28)
wbDTD121 (In(2LR)DTD121)
wbH68 (T(2;3)H68)
misc_allele:
wbIK4
phenotypic_class: behavioural.
SM_notes: Translation from alignment of GenBank AF135118.1 on DS03792 (5';
1-3644) and
on DS01068 (3'; 3645-10817). n(2)k16716 (viable over deletion but
phenotypically wb) maps to 53181 of DS03792, smi35A to 53174,
rff(2)k06901 to 53160, l(2)09437 to 15219, n(2)rL918 to 14850.
phenotypic_notes: escapers or weak alleles with wing blister phenotype.
phenotypic_class: vital.
JR_notes: product data from Baumgartner & Prokop.
===========================================================================
symbol: ms(2)34Fe
name: male sterile (2) 34Fe
synonym: ms(2)34Fh
UID: FBgn0002822
references:
FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119
cytology: 35A1--35A4
cytology_data: Left limit from complementation mapping against T(2;3)GT10
(citat
ion unavailable)
cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0091422)
misc_allele:
ms(2)34Fe1
phenotypic_class: male_sterile.
JR_notes: 34Fe = 34Fh because these classes male sterile
(b78j/do-1,b78j/el15,b78j/ms(2)34Fe1715,do-1/ms(2)34Fe1715,el15/ms(2)34Fe1715)
and these classes male fertile
(b85f1/do-1,b79b4/do-1,b85f1/el15,b79b4/el15,b85f1/ms(2)34Fe1715,b79b4/ms(2)34
Fe1715) since ms(2)34Fh
was inferred from b78j/do-1 and b78j/el15 being ms.
===========================================================================
symbol: l(2)34Fc
name: lethal (2) 34Fc
UID: FBgn0001968
cytology: 35A1--35A4
cytology_data: Left limit from inclusion within Df(2L)A217 (FBrf0038050)
cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0038047)
gamma_ray_allele:
T(2;3)GT10
ems_allele:
l(2)34Fc1
l(2)34Fc2
l(2)34Fc3
l(2)34Fc4
l(2)34Fc5
l(2)34Fc6
l(2)34Fc7
l(2)34Fc8
l(2)34Fc9
l(2)34Fc10
l(2)34FcOK9
phenotypic_class: vital.
JR_notes: the synthetic deletion GT10 TE35BC-GV8 is hypomorphic for 34Fc,
thus GT10 breaks in 34Fc.
JR_notes: 3/37 excisions of k08712=Rab14 lethal; all lethal excisions
34Fd- or 35Aa-; therefore gene order is 34Fe, 34Fd, Rab14, 35Aa.
===========================================================================
symbol: l(2)34Fd
name: lethal (2) 34Fd
UID: FBgn0001969
references:
FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119
cytology: 35A1--35A4
cytology_data: Left limit from inclusion within Df(2L)A217 (FBrf0038050)
cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0091422)
ems_allele:
l(2)34Fd1
l(2)34Fd2
l(2)34Fd3
l(2)34Fd4
l(2)34Fd5
l(2)34Fd6
l(2)34Fd7
l(2)34Fd8
l(2)34Fd9
l(2)34FdCH35
phenotypic_class: vital.
JR_notes: 3/37 excisions of k08712=Rab14 lethal; all lethal excisions
34Fd- or 35Aa-; therefore gene order is 34Fe, 34Fd, Rab14, 35Aa.
===========================================================================
\+symbol:  BG:DS03792 .2
\+formal_name:  BG:DS03792 .2
genefinder: (20)
genscan: 109
product:
match_to: LD23113.5' e-7
EST:
P1: DS03792
direction: +
Nested_in: wb
SM_notes: Translation from Genscan. Could be ms(2)34Fe.
===========================================================================
\+symbol:  BG:DS01068 .1
\+formal_name:  BG:DS01068 .1
genefinder: 100
genscan: 397
product:
match_to:
EST:
P1: DS01068
direction: +
SM_notes: Could be ms(2)34Fe or l(2)34Fc.
==========================================================================
\+symbol:  BG:DS01068 .11
\+formal_name:  BG:DS01068 .11
genefinder: (17)/172*(1 span)
genscan: 487*(2 spans)
product:
match_to: GB AA313794 e-16 H (Homo EST)
match_to: GB AA087241 e-14 M (Mus EST)
match_to: SP P34664 e-10 W
match_to: LD22379.5' e-22; LD34776.5' e-21; LD31155.5' e-21; LD06669.5'
e-21; LD16573.5' e-21;LD16570.5' e-21;LD10017.5' e-21; LD21139.5'
e-21;LD17209.5' e-21;LD17733.5' e-21 D (Dros EST)
EST: GH05919.3'
P1: DS01068
direction: +
SM_notes: Translation from edited Genscan on 5' end and G05919.3' on 3'
end. Could be ms(2)34Fe or l(2)34Fc.
==========================================================================
\+symbol:  BG:DS01068 .2
\+formal_name:  BG:DS01068 .2
genefinder: 172*(6 spans)
genscan: 487*(6 spans)
product:
match_to: TR O01893 e-101 W
match_to: TR P73619 e-63 B (Synechoscystis sp.)
match_to: GB R13905 e-18 H (Homo EST)
match_to: GB T08003 e-18 H (Homo EST)
match_to: GB AA451516 e-15 M (Mus EST)
match_to: GB T76924 e-11 A (Arab EST)
EST:
P1: DS01068
direction: +
SM_notes: Translation from edited Genscan. Could be ms(2)34Fe or l(2)34Fc.
==========================================================================
\+symbol:  BG:DS01068 .10
\+formal_name:  BG:DS01068 .10
genefinder: 38
genscan: 30
product: similar to trypsin (serine protease)
match_to: SP P15948 e-24 M
match_to: SP P42278 e-31 D
match_to: SP P54628 e-31 O (Drosophila erecta)
EST:
P1: DS01068
direction: -
SM_notes: Translation from Genscan. Could be ms(2)34Fe or l(2)34Fc.
==========================================================================
\+symbol:  BG:DS01068 .4
\+formal_name:  BG:DS01068 .4
genefinder: 41
genscan: 92
product:
match_to:
EST: LD33443.5'; LD22904.5'
P1: DS01068
direction: -
SM_notes: Translation from full-length LD33443. Could be ms(2)34Fe or
l(2)34Fc.
==========================================================================
\+symbol:  BG:DS01068 .5
\+formal_name:  BG:DS01068 .5
genefinder: 35
genscan: 382* (2 spans)
product:
match_to:
EST:
P1: DS01068
direction: -
SM_notes: Translation from Genefinder. Could be ms(2)34Fe, l(2)34Fc, or
l(2)34Fd.
==========================================================================
\+symbol:  BG:DS01068 .6
\+formal_name:  BG:DS01068 .6
genefinder: 112
genscan: 382* (4 spans)
product:
match_to: TR Q19974 e-108 W (worm EST)
match_to: SP P48234 e-82 Y
match_to: GB Z72930 e-74 Y
match_to: GB AA107580 e-41 M (Mus EST)
match_to: GB X83354 e-25 M (Mus EST)
match_to: GB AA314293 e-33 H (Hum EST)
EST: LD09509.3'; LD09509.5'; GM05483.5'; GM06063.5'; GM08820.5';
LD21252.5'; LD32056.5'
P1: DS01068
direction: -
SM_notes: Translation from full-length LD09509. Best bet for 34Fd.
JR_notes: Was thought to be broken by T(2;3)GT10 by in situ with LD09509,
but
this data disagrees with genetic data showing GT10 breaks in 34Fc.
===========================================================================
\+symbol: Rab14
\+formal_name:  BG:DS01068 .7
full name: Rab-protein 14
synonym:  ESTS:57H4T 
UID: FBgn0015791
cytology: 36A--36B
references:
FBrf0098074 == Ozaki, 1997.8.1
FBrf0093208 == Satoh et al., 1997, FEBS Lett. 404(1): 65--69
FBrf0077724 == Kohno et al., 1993, Zool. Sci., Tokyo 10: 119
FBrf0080163 == Kohno et al., 1994, Zool. Sci., Tokyo 11: 99
FBrf0086498 == Kono et al., 1995, Zool. Sci., Tokyo 12: 113
P_element_allele:
n(2)k08712 sequenced
genefinder: 39
genscan: 55
product: Rab14
match_to: SP P35287 e-79 M (rat)
match_to: TR Q93874 e-73 W
match_to: SP P20338 e-48 H
match_to: GB AA214461 e-30 H (Hum EST)
match_to: SP P38555 e-36 Y
match_to: TR O23657 e-24 A
EST: LD03340.3'; LD03340.5'; LD32887.5'; LD29476.5'; LD26806.5'
P1: DS01068
direction: +
cDNA_sequence: D84316
pr_sequence_SPTREMBL: O18336
phenotypic_class: not vital
JR_notes: 3/37 excisions of k08712 lethal; all lethal excisions 34Fd- or
35Aa-,
indicating that Rab14 is between 34Fd and 35Aa. Since 35Aa- deletion is
rescued by a
5-kb GalNac (=35Aa) fragment (from Flores), and P in 5' end of Rab 14,
Rab14 not vital.
SM_notes: Translation from full-length LD03340 (longer than GenBank
D84316). n(2)k08712 inserted at 39329 of DS01068; Rab14 at 39278-42449.
===========================================================================
\+symbol: l(2)35Aa
\+formal_name:  BG:DS01068 .8
UID: FBgn0001970
references:
FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119
cytology: 35A3--35A4
cytology_data: Left limit from inclusion within Df(2L)TE35B-7 (FBrf0051916)
cytology_data: Right limit from inclusion within Df(2L)b80e3 (FBrf0091422)
enzyme: polypeptide N-acetylgalactosaminyltransferase == EC 2.4.1.41
genefinder: 107
genscan: 263
match_to: TR Q10471 e-91 H
match_to: GB X85019 e-83 H
match_to: TR G3047191 e-91 W
match_to: TR G3047193 e-91 W
match_to: TR G3047195 e-91 W
match_to: TR O08912 e-89 M
EST: LD24449.5'
P1: DS01068
direction: +
ems_allele:
l(2)35Aa1
l(2)35Aa2
l(2)35Aa3
l(2)35Aa4
l(2)35Aa5
l(2)35Aa6
l(2)35Aa7
phenotypic_class: vital.
phenotypic_notes: early pupal lethal.
SM_notes: Translation from full-length LD24449.
JR_notes: Product & transformation rescue information from Flores (chez
Engels).
===========================================================================
\+symbol: spel1
\+formal_name:  BG:DS01068 .9
name: spellchecker1
UID: FBgn0015546
references:
FBrf0078419 == rd1552 == Flores and Engels, 1995, A. Conf. Dros. Res.
36: 204A
cytology: 35A1--35A1
cytology_data: Left limit from inclusion within Df(2L)A217 (FBrf0038050)
cytology_data: Right limit from sequence databank entry U17893
genefinder: 83(DS01068);33(DS06238)
genscan: 211(DS01068);33(DS06238)
match_to: SP P43246 e-97(DS01068)/e-70(DS06238) H
match_to: GB U04045 e-84(DS01068)/e-64(DS06238) H
match_to: SP P43247 e-92(DS01068)/e-68(DS06238) M
match_to: TR O24617 e-60(DS01068)/e-56(DS06238) A
match_to: SP P25847 e-50(DS01068)/e-60(DS06238) Y
EST: LD33650.5'; GM13404.5'; LD14009.5'
P1: DS01068, DS06238
direction: +
motifs: PS00486 == DNA mismatch repair proteins mutS family signature.
homology: species == Escherichia coli; gene == mutS; ECOGENE: EG10625
homology: species == Mus; gene == Msh2; MGD: MRK-18634
homology: species == Homo sapiens; gene == MSH2; GDB: 203983; OMIM: 120435
 cDNA_sequence:U17893 ; g675456 partial
 pr_sequence_SwissProt:P43248 
phenotypic_class: non_vital.
SM_notes: Translation from alignment of GenBank U17893 on DS01068 & DS06238.
===========================================================================
\+symbol: ppk
\+formal_name:  BG:DS06238 .1
name: pickpocket
synonym: mdNaC1
UID: FBgn0020258
cDNA_sequence: Y16225; e1237841
cDNA_sequence: AF043263; g2811254
 pr_sequence_TREMBL:O46104 
 pr_sequence_TREMBL:O44940 
genefinder: (9)/28
genscan: 132
product: epithelial sodium channel.
match_to: TR AF043264 e-61 D
EST:
P1: DS06238
direction: -
SM_notes: Translation from alignment of GenBank on AF043263.
==========================================================================
\+symbol: elB
\+formal_name:  BG:DS06238 .3
name: elbow B
UID: FBgn0004858
references:
FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119
cytology: 35A4--35A4
cytology_data: Left limit from inclusion within Df(2L)TE35B-14 (FBrf0092813)
cytology_data: Right limit from inclusion within Df(2L)b83d29a (FBrf0051916)
genefinder: 74
genscan: 199
product: noc-like Zinc-finger protein
match_to: TR Q24423 e-59 D
match_to: TR Q41805 e-7 O (Zea mays)
EST:
P1: DS06238
direction: -
spontaneous_allele:
see elA
ems_allele:
see elA
gamma_ray_allele:
see elA
elB8
X_ray_allele:
aberration_associated_allele:
elB4 (T(Y;2)el4)
elB6 (In(2LR)el6)
elB7 (T(2;3)dpps19)
elB9 (In(2L)el9)
elB5 (T(Y;2)a15)
P_element_allele:
EP(2)2039 sequenced (elbow over a deletion)
EP(2)0965 sequenced
k07706 sequenced
phenotypic_notes: reduced posterior compartment in wing; very similar, but
complements, elA.
SM_notes: Translation from Genscan. EP(2)2039 & sequence from Cohen at
45657 of DS06238; EP(2)0965 at
45828; k07706 at 45738.
==========================================================================
\+symbol:  BG:DS06238 .4
\+formal_name:  BG:DS06238 .4
genefinder: 30
genscan: 63
product: larval cuticle protein
match_to: GB M71249 e-11 D (Edg84A)
match_to: SP P04929 e-33 O (Plasmodium lophurae) (His-rich, repeat segment)
match_to: TR Q92504 e-11 H (His-rich, repeat segment)
match_to: TR D1012195 e-11 H (His-rich, repeat segment)
match_to: SP Q31125 e-11 M (His-rich, repeat segment)
match_to: TR O35957 e-11 M
match_to: TR O18272 e-9 W
EST:
P1: DS06238
direction: -
SM_notes: Translation from Genscan.
MA_notes: Best bet for pu, since matches Edg84A.
==========================================================================
\+symbol:  BG:DS08340 .1
\+formal_name:  BG:DS08340 .1
genefinder: (9)
genscan: (42)
product:
match_to: GB AA419695 e-8 M (Mus EST)
match_to: GB AA778038 e-8 H (Hum EST)
match_to: GH12842.5' e-19; LP06079.5' e-19; LP02268.5' e-19; GH06541.5'
e-19; GH10679.5' e-19 D
EST:
P1: DS08340
direction: -
SM_notes: Translation from Genscan.
MA_notes: Best bet for elA.
==========================================================================
symbol: pu
name: pupal
UID: FBgn0003161
references:
FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119
cytology: 35B1--35A4+
cytology_data: Left limit from complementation mapping against T(2;3)GT3
(citation unavailable)
cytology_data: Right limit from inclusion within Df(2L)b83d29a (FBrf0051916)
spontaneous_allele:
pu1
ems_allele:
pu2
pu3
pu4
pu5
pu6
pu7
phenotypic_notes: wings unexpanded.
phenotypic_class: visible; non_vital.
===========================================================================
symbol: elA
name: elbow A
UID: FBgn0004857
references:
FBrf0051916 == Davis et al., 1990, Genetics 126: 105--119
cytology: 35B1--35B1
cytology_data: Left limit from inclusion within Df(2L)ARR1 (FBrf0051916)
cytology_data: Right limit from inclusion within Df(2L)b81a1 (FBrf0038047)
spontaneous_allele:
elA1 (25-kb deletion)
ems_allele:
elA2
elA3
elA21
elA22
elA23
elA27
elA29
elA30
gamma_ray_allele:
elA8
elA10
elA11
elA12
elA25
elA26
aberration_associated_allele:
elA24 (T(2;3)el24)
phenotypic_notes: reduced posterior compartment in wing; very similar, but
complements, elB.
phenotypic_class: visible; non_vital.
===========================================================================
\+symbol: noc
\+formal_name:  BG:DS04641 .1
name: no ocelli
UID: FBgn0005771
references:
FBrf0066938 == Cheah et al., 1994, Molec. Cell. Biol. 14: 1487--1499
FBrf0043115 == Chia et al., 1985, J. molec. Biol. 186: 689--706
FBrf0087599 == McNabb et al., 1996, Genetics 143(2): 897--911
cytology: 35B1+--35B1+
cytology_data: Left limit from inclusion within Df(2L)A178 (FBrf0038047)
cytology_data: Right limit from inclusion within Df(2L)b81a1 (FBrf0038047)
motifs: Zinc finger protein.
genefinder: 88
genscan: 179
match_to: TR Q90237 e-11 O (Anolis pulchellus)
match_to: SP P32323 e-7 Y
EST: GM07914.5'; LD28078.5'; LD28077.5'
P1: DS04641
direction: +
 cDNA_sequence:L14009 ; g457883
 pr_sequence_TREMBL:Q24423 
 pr_sequence_PIR:A55929 
ems_allele:
noc18
noc19
noc22
noc23
noc35Ba-1
noc35Ba-2
noc35Ba-3
noc35Ba-4
nocSco-rv15
TE_insert_allele:
nocTE35B (TE146)
X_ray_allele:
nocSco-rv27
gamma_ray_allele:
noc14
noc15
noc21
noc6
aberration_associated_allele:
noc2 (In(2L)noc2)
noc4 (In(2LR)noc4)
noc7 (In(2LR)noc7)
nocGT8 (T(2;3)GT8)
nocSco (Tp(2;2)Sco)
nocSco-rv1 (In(2LR)Scorv1)
nocSco-rv2 (In(2L)Scorv2)
nocSco-rv5 (In(2L)Scorv5)
nocSco-rv8 (In(2L)Scorv8)
nocSco-rv9 (In(2LR)Scorv9)
nocSco-rv11 (In(2L)Scorv11)
nocSco-rv12 (Tp(2;2)Scorv12)
nocSco-rv13 (T(2;3)Scorv13)
nocSco-rv17 (In(2L)Scorv17)
nocSco-rv21 (In(2L)Scorv21)
nocSco-rv23 (Tp(2;1)Scorv23)
nocSco-rv24 (In(2L)Scorv24)
nocSco-rv26 (In(2L)Scorv26)
TE146 derivatives
P_element_allele:
EP(2)2000 sequenced
EP(2)2173 sequenced
phenotypic_notes: visible phenotype is loss of ocelli; lethal may show
failure of head involution; Sco is antimorphic allele.
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank L14009.
===========================================================================
\+symbol:  BG:DS04641 .2
\+formal_name:  BG:DS04641 .2
genefinder:
genscan:
tRNAscan-SE: 57
product: tRNA-pro
match_to: (GB M26848 e-6 M)
EST:
P1: DS04641
direction: +
==========================================================================
\+symbol:  tRNA:G3:35Ba 
\+formal_name:  BG:DS04641 .3
name: transfer  RNA:gly3:  35Ba
UID: FBgn0011862
references:
FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189
cytology: 35B1--35B2
genefinder:
genscan:
tRNAscan-SE: 72
product: tRNA-gly3
match_to: (GB Z14135 e-6 O (Bombyx mori))
match_to: (GB Z15047 e-6 O (Bombyx mori))
EST:
P1: DS04641
direction: +
 na_sequence:X07778 
===========================================================================
\+symbol:  tRNA:G3:35Bb 
\+formal_name:  BG:DS04641 .4
name: transfer  RNA:gly3:  35Bb
UID: FBgn0011863
references:
FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189
cytology: 35B1--35B2
genefinder:
genscan:
tRNAscan-SE: 72
product: tRNA-gly3
match_to: GB M13661 e-9 H
match_to: GB Z49226 e-12 O (Bombyx mori)
match_to: TR O17337 e-8 W
EST:
P1: DS04641
direction: -
 na_sequence:X07778 
===========================================================================
\+symbol:  tRNA:G3:35Bc 
\+formal_name:  BG:DS04641 .5
name: transfer  RNA:gly3:  35Bc
UID: FBgn0011864
references:
FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189
cytology: 35B1--35B2
genefinder:
genscan:
tRNAscan-SE: 72
product: tRNA-gly3
match_to: GB M13661 e-9 H
match_to: GB Z49226 e-12 O (Bombyx mori)
EST:
P1: DS04641
direction: -
 na_sequence:X07779 
===========================================================================
\+symbol:  tRNA:G3:35Bd 
\+formal_name:  BG:DS04641 .6
name: transfer  RNA:gly3:  35Bd
UID: FBgn0011865
references:
FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189
cytology: 35B1--35B2
genefinder:
genscan:
tRNAscan-SE: 72
product: tRNA-gly3
match_to: GB M13661 e-9 H
match_to: GB Z49226 e-12 O (Bombyx mori)
EST:
P1: DS04641
direction: -
 na_sequence:X07779 
===========================================================================
\+symbol:  tRNA:G3:35Be 
\+formal_name:  BG:DS04641 .7
name: transfer  RNA:gly3:  35Be
UID: FBgn0011866
references:
FBrf0048836 == Meng et al., 1988, Nucleic Acids Res. 16: 7189
cytology: 35B1--35B2
genefinder:
genscan:
tRNAscan-SE: 68
product: tRNA-gly3
match_to: GB M13661 e-9 H
match_to: GB Z49226 e-12 O (Bombyx mori)
EST:
P1: DS04641
direction: -
 na_sequence:X07779 
==========================================================================
\+symbol:  BG:DS04641 .8
\+formal_name:  BG:DS04641 .8
genefinder: 27
genscan: 94
product:
match_to:
EST:
P1: DS04641
direction: -
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS01486 .1
\+formal_name:  BG:DS01486 .1
genefinder: (8)
genscan: (44)
product: ubiquitin--protein ligase
match_to: SP Q16781 e-60 H
match_to: SP P52490 e-50 Y
match_to: GB AA271547 e-45 M (Mus EST)
match_to: GB U62483 e-26 M
match_to: SP P35129 e-31 W
match_to: GB S70118 e-44 D
match_to: GB L20126 e-44 D
match_to: SP P35132 e-30 A
match_to: LD24448.5' e-43; LD16328.c e-43; GM02759.5' e-43;LD14534.5'e-40;
LD31794.5' e-35
EST:
P1: DS01486
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS01486 .2
\+formal_name:  BG:DS01486 .2
genefinder:
genscan:
tRNAscan-SE: 57
product: transfer  RNA:pro 
match_to: GB X55888 e-9 O (chicken)
EST:
P1: DS01486
direction: +
==========================================================================
\+symbol:  BG:DS01486 .3
\+formal_name:  BG:DS01486 .3
genefinder:
genscan:
tRNAscan-SE: 57
product: transfer  RNA:pro 
match_to: GB X55888 e-10 O (chicken)
EST:
P1: DS01486
direction: -
==========================================================================
\+symbol:  BG:DS01486 .4
\+formal_name:  BG:DS01486 .4
genefinder:
genscan:
tRNAscan-SE: 57
product: transfer  RNA:pro 
match_to: GB X55888 e-9 O (chicken)
EST:
P1: DS01486
direction: +
==========================================================================
\+symbol: osp
\+formal_name:  BG:DS01486 .7
synonym:  BG:DS01486 .5
synonym:  BG:DS07721 .2
name: outspread
UID: FBgn0003016
references:
FBrf0087599 == McNabb et al., 1996, Genetics 143(2): 897--911
cytology: 35B3--35B3
cytology_data: Left limit from complementation mapping against T(2;3)GT7
(citation unavailable)
cytology_data: Right limit from inclusion within Df(2L)A178 (FBrf0038047)
genefinder: 94/34(DS01486); 9(DS07721)
genscan: 431(DS01486); (30)* (2 spans)(DS07721)
match_to: TR P97434 e-18 M (p116Rip)
match_to: GB AA118415 e-10 M (Mus EST)
match_to: SP P11055 e-10 H (myosin heavy chain)
match_to: SP P13535 e-10 H (myosin heavy chain)
match_to: TR Q20042 e-10 W
match_to: TR Q18082 e-9 W (myosin heavy chain)
match_to: SP P25386 e-8 Y
EST: LD14119.5'; LD14119.3'; LD13781.5'; CK02594.5'; LD15891.5'; LD15891.3'
P1: DS01486, (DS09219), DS07721
direction: -
 na_sequence:M14802 ; g552081
 na_sequence:M17837 ; g903720
 na_sequence:Z00030 ; g7559
 pr_sequence_TREMBL:Q24231 
 pr_sequence_TREMBL:Q27421 
ems_allele:
osp1
osp16
osp19
osp24
osp25
osp27
osp4
osp6
osp7
osp76e
osp77e
osp8
ospCH63
diepoxyoctane_allele:
osp80.1D
P_element_allele:
osprJ571 sequenced
l(3)00865 sequenced
k13218 sequenced
gamma_ray_allele:
osp104
osp201
osp29
osp35
osp40
osp83
aberration_associated_allele:
osp22 (In(2L)osp22)
osp3 (Tp(2;3)osp3)
osp29 (Df(2L)osp29)
osp59 (In(2L)osp59)
osp90 (T(2;3)osp90)
ospH47 (T(2;3)H47)
ospMpe (T(2;3)Mpe)
osppb3 (T(2;3)pb3)
ospH86 (In(2L)dppH86)
misc_allele:
ospalw
phenotypic_notes: wings outspread; not vital.
phenotypic_class: visible; non_vital.
MA_notes: includes  BG:DS01486 .6; Note that k13218 is not a phenotypic osp
allele.
SM_notes: Appears to be alternatively spliced: translation of osp-LD14119
from complete sequence LD14119 (not full-length on 5' end?), doesn't use
penultimate
exon of LD15891 but does use last exon (longer 3').
Translation of osp-3prime from full-length LD15891 on DS01486 (838-5324),
osp-5prime on DS07721.
===========================================================================
\+symbol: Adh
\+formal_name:  BG:DS01486 .8
name: Alcohol dehydrogenase
UID: FBgn0000055
cytology: 35B3--35B3
cytology_data: Left limit from non-inclusion within Df(2L)TE35B-8 (FBrf0087599)
cytology_data: Right limit from inclusion within Df(2L)A178 (FBrf0038047)
enzyme: alcohol dehydrogenase == EC 1.1.1.1
genefinder:
genscan: 132* (1 span)
match_to: SP P15428 e-11 H
match_to: TR Q61106 e-10 M
EST: HL01670.5'; HL05782.5'; GH01616.5'
P1: DS01486
direction: +
motifs: PS00061 == Short-chain alcohol dehydrogenase family signature.
 na_sequence:J01066 
 na_sequence:M14802 ; g156803
 na_sequence:M17827 ; g156860
 na_sequence:M17828 ; g156862
 na_sequence:M17830 ; g156866
 na_sequence:M17831 ; g156868
 na_sequence:M17832 ; g156870
 na_sequence:M17833 ; g156872
 na_sequence:M17834 ; g156874
 na_sequence:M17835 ; g156876
 na_sequence:M17836 ; g156878
 na_sequence:M17837 ; g156880
 na_sequence:M17845 ; g156906
 na_sequence:M19547 ; g156864
 na_sequence:M22210 ; g156839
 na_sequence:M29635 
 na_sequence:M29636 ; e124826
 na_sequence:M36580 ; g156805
 na_sequence:M57239 ; g156800
 na_sequence:M71284 
 na_sequence:M73256 
 na_sequence:U20765 ; g684944
 na_sequence:U35852 
 na_sequence:X04454 
 na_sequence:X15607 
 na_sequence:X60791 ; g8152
 na_sequence:X60792 ; g8441
 na_sequence:X60793 ; g8282
 na_sequence:X66233 
 na_sequence:X78384 ; e315259
 na_sequence:X78385 
 na_sequence:X78386 
 na_sequence:X78387 
 na_sequence:X78402 
 na_sequence:X78916 
 na_sequence:X78917 
 na_sequence:X98338 ; e248823
 na_sequence:Z00030 ; g599727
 pr_sequence_SwissProt:P00334 
 pr_sequence_TREMBL:Q27332 
 pr_sequence_TREMBL:Q27579 
 pr_sequence_TREMBL:Q27596 
 pr_sequence_PIR:A37092 
 pr_sequence_PIR:B93309 
 pr_sequence_PIR:A93713 
 pr_sequence_PIR:A93875 
 pr_sequence_PIR:A93309 
 pr_sequence_PIR:A93873 
 pr_sequence_PIR:S17083 
 pr_sequence_PIR:S17084 
phenotypic_class: visible; non_vital.
Nested_in: osp
SM_notes: Translation from alignment of trEMBL Q27332.
===========================================================================
\+symbol: Adhr
\+formal_name:  BG:DS01486 .9
name: Adh-related
UID: FBgn0000056
references:
Brogna, EMBO J. 16: 2023-2031
cytology: 35B3--35B3
cytology_data: Left limit from non-inclusion within Df(2L)TE35B-8 (FBrf0091422)
cytology_data: Right limit from inclusion within Df(2L)A178 (FBrf0091422)
genefinder: (15)
genscan: 132* (2 spans)
product: alcohol-dehydrogenase \like
match_to: SP P15428 e-11 H
match_to: TR Q61106 e-10 M
EST: GM04306.5'
P1: DS01486
direction: +
 na_sequence:M14802 ; g765036
 na_sequence:Z00030 
 na_sequence:X78384 ; g483719
 na_sequence:X98338 ; e248898
 pr_sequence_TREMBL:Q24230 
 pr_sequence_TREMBL:Q24232 
phenotypic_notes: complete deletion associated with malformation of gastric
caecea.
phenotypic_class: visible; non_vital.
Nested_in: osp
SM_notes: Translation from alignment of SwissProt P91615.
==========================================================================
\+symbol:  BG:DS09219 .1
\+formal_name:  BG:DS09219 .1
genefinder:
genscan: (41)(DS09219)/(34)(DS07721)
product:
match_to:
EST:
P1: DS09219, DS07721
direction: -
Nested_in: osp
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS07721 .1
\+formal_name:  BG:DS07721 .1
genefinder:
genscan:
product:
match_to:
EST: CK02594.5'; CK02594.3'
P1: DS07721
direction: +
Nested_in: osp
SM_notes: Translation from full-length CK02594.
===========================================================================
\+symbol:  BG:DS07721 .3
\+formal_name:  BG:DS07721 .3
genefinder: 21
genscan: 47/(44)
product:
match_to: LP02495.5' e-8; LP04185.5' e-8; LP03565.5' e-8; LP03436.5' e-8
EST:
P1: DS07721
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS07721 .6
\+formal_name:  BG:DS07721 .6
genefinder:
genscan: 271
match_to:
EST:
P1: DS07721
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS00810 .1
\+formal_name:  BG:DS00810 .1
genefinder: 25
genscan: 97
product:
match_to: GB AA313794 e-14 H (Homo EST)
match_to: SP P34664 e-14 W
match_to: GB AA087241 e-10 M (Mus EST)
match_to: LD20357.5' e-13;LD22379.5' e-12;LD34776.5' e-12;LD31155.5'
e-12;LD16573.5' e-12;LD16570.5' e-12;LD06669.5' e-12;LD21139.5'
e-12;LD28856.5' e-12;LD15550.5' e-12
EST:
P1: DS00810
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS00810 .2
\+formal_name:  BG:DS00810 .2
genefinder: (19)
genscan:
product: ribosomal protein 15a
match_to: GB Z21673 e-47 D
match_to: LD11847.3' e-25; GM02304.5' e-27; GM04832.5' e-25; GM06369.5'
e-54; GM13983.5' e-48; HL07857.5' e-43; LD03678.5' e-25; LD04294.5' e-21;
LD07181.5' e-50; LD14972.5' e-25; LD33594.5' e-48; GH04971.3' e-45
EST: LP03565.5'; LP04185.5'; LP02495.5'; LP04636.3'; LP06216.3'; LP03436.5'
P1: DS00810
direction: -
SM_notes: Translation from full-length LP03565.
==========================================================================
\+symbol:  BG:DS00810 .3
\+formal_name:  BG:DS00810 .3
genefinder: (16)
genscan: (14)
product:
match_to: SP Q25055 e-10 O
match_to: SP P17816 e-12 O
match_to: TR O02049 e-9 W
EST: GH13704.5'; GH07880.5'; LP02868.5'; LP03582.5'
P1: DS00810
direction: +
SM_notes: Translation from complete sequence GH13704 at 5' (not full-length
clone?) and GH07880.5' EST at 3'..
===========================================================================
\+symbol:  BG:DS06874 .1
\+formal_name:  BG:DS06874 .1
genefinder: 27
genscan: 59
product:
match_to:
EST:
P1: DS06874
direction: +
SM_notes: Translation from Genefinder.
==========================================================================
\+symbol:  BG:DS06874 .2
\+formal_name:  BG:DS06874 .2
genefinder: (19)
genscan: 111
product:
match_to: SP P97834 e-58 (rat)
match_to: GB X87885 e-57 (rat)
match_to: SP Q13098 e-56 H
match_to: SP P45432 e-37 A
match_to: GB W65922 e-13 M (Mus EST)
EST:
P1: DS06874
direction: +
SM_notes: Translation from Genscan.
MA_notes: Fusca; GPS1 homolog see MCB 16: 6698-6706
===========================================================================
\+symbol:  BG:DS06874 .3
\+formal_name:  BG:DS06874 .3
genefinder: 44
genscan: 127
product: MSP1 homolog (TAT-binding)
match_to: SP P54815 e-62 W
match_to: YPD 1323004 e-62 Y
match_to: GB X68055 e-56 Y
match_to: GB X81069 e-58 Y
match_to: TR G3193292 e-50 A
match_to: GB AA028745 e-36 M (Mus EST)
match_to: GB AA268776 e-36 M (Mus EST)
match_to: TR G2984586 e-33 H
match_to: TR G3283072 e-33 H
match_to: SP P91638 e-33 D
match_to: GH13949.5' e-58; LP05581.5' e-39; GH08677.5' e-39; LD20618.5'
e-22;GM07738.5' e-12;GM05721.5' e-15;GM04824.5' e-12;CK00306.5' e-28
EST:
P1: DS06874
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS06874 .4
\+formal_name:  BG:DS06874 .4
genefinder: (16)
genscan: 103*(2 spans)
product: serine protease
match_to: SP P40313 e-13 H
match_to: TR D1029835 (AB015206) e-11 M
match_to: SP P05049 e-10 D
EST:
P1: DS06874
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS06874 .6
\+formal_name:  BG:DS06874 .6
genefinder:
genscan: (35)
product: serine protease
match_to: TR D1029835 (AB015206) e-8 M
match_to: SP P40313 e-13 H
EST:
P1: DS06874
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS06874 .7
\+formal_name:  BG:DS06874 .7
genefinder:
genscan: 119
product:
match_to:
EST:
P1: DS06874
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS03431 .1
\+formal_name:  BG:DS03431 .1
genefinder: 55
genscan: 111
product: proline transporter
match_to: TR G3252836 e-115 O (tobacco hornworm)
match_to: SP P51905 e-74 D
match_to: SP Q99884 e-69 H
match_to: TR Q99884 e-69 H
match_to: SP P31659 e-63 M
match_to: TR O17372 e-54 W
match_to: LD18557.5' e-31
EST:
P1: DS03431
direction: -
SM_notes: Translation from Genscan. ether resistant P-element insert; may
or may-not be this.
===========================================================================
\+symbol: Mst35Ba
\+formal_name:  BG:DS03431 .2
name: Male-specific-transcript-35Ba
references:
FBrf0058368 == Russell and Kaiser, 1993, Europ. Dros. Res. Conf. 13: n.p.
cytology: 35B1--35B10
genefinder:
genscan:
product: protamine \like
match_to: SP P17502 e-7 O (boll weevil)
EST:
P1: DS03431
direction: -
 cDNA_sequence:Z46790 ; g608696
 genomic_sequence:Z46783 ; g608700
 pr_sequence_TREMBL:Q24401 
 pr_sequence_TREMBL:Q24405 
 pr_sequence_PIR:S52155 
 pr_sequence_PIR:S52157 
SM_notes: Translation from GenBank Z46790.
===========================================================================
\+symbol: Mst35Bb
\+formal_name:  BG:DS03431 .3
name: Male-specific-transcript-35Bb
references:
FBrf0058368 == Russell and Kaiser, 1993, Europ. Dros. Res. Conf. 13: n.p.
cytology: 35B1--35B10
genefinder: (11)
genscan:
product: protamine \like
match_to:
EST:
P1: DS03431
direction: -
 cDNA_sequence:Z46784 ; g608698
 genomic_sequence:Z46785 ; g608702
 pr_sequence_TREMBL:Q24402 
 pr_sequence_TREMBL:Q24406 
 pr_sequence_PIR:S52156 
 pr_sequence_PIR:S52158 
SM_notes: Translation from GenBank Z46784.
===========================================================================
symbol: ms(2)35Bi
JR_notes: Inferred from deletion o/laps.
===========================================================================
\+symbol:  BG:DS03144 .1
\+formal_name:  BG:DS03144 .1
genefinder: 49/(11)
genscan: 123
product:
match_to:
EST:
P1: DS03144
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS03323 .1
\+formal_name:  BG:DS03323 .1
genefinder: 102(DS03323)
genscan: 133(DS03144);405(DS03323)
product: strawberry-notch-like
match_to: GB U95760 e-197 D (sno)
match_to: TR O01737 e-241 W
match_to: TR G3152595 e-176 A
match_to: GB AA413592 e-51 M (Mus EST)
match_to: GB W25975 e-31 H (Hum EST)
match_to: HL01650.5' e-24
EST:
P1: DS03144, DS03323
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS01219 .3
\+formal_name:  BG:DS01219 .3
genefinder: (10)
genscan: 99
product:
match_to:
EST:
P1: DS01219
direction: -
SM_notes: Translation from Genscan.
===========================================================================
symbol: l(2)35Bb
name: lethal (2) 35Bb
UID: FBgn0001972
references:
FBrf0087599 == McNabb et al., 1996, Genetics 143(2): 897--911
cytology: 35B4--35B4
cytology_data: Left limit from inclusion within Df(2L)TE35BC-34 (FBrf0091422)
cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544)
spontaneous_allele:
l(2)35Bb6
ems_allele:
l(2)35Bb1
l(2)35Bb2
l(2)35Bb3
l(2)35Bb4
l(2)35Bb5
l(2)35Bb7
l(2)35Bb8
l(2)35Bb9
neutron_induced_allele:
l(2)35Bb10
P_element_induced_allele:
l(2)35Bbk11524 sequenced(DS00929)
phenotypic_class: vital.
SM_notes: k11524p inserted at 5037 of DS00929, in ORF of  BG:DS00929 .16, but
 BG:DS01219 .1 ESTs from 1533-1359 of DS00929.
===========================================================================
symbol: l(2)35Bf
name: lethal (2) 35Bf
UID: FBgn0001976
references:
cytology: 35B4--35B4
cytology_data: Left limit from inclusion within Df(2L)TE35BC-4 (FBrf0038053)
cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544)
ems_allele:
l(2)35Bf1
l(2)35Bf2
l(2)35Bf3
l(2)35Bf4
l(2)35Bf5
l(2)35Bf6
l(2)35Bf7
l(2)35Bf8
l(2)35BfQL53
phenotypic_class: vital.
JR_notes: Excision of k08808=l(2)35Bc indicates gene order is 35Bb, 35Bf,
35Be, 35Bc, 35Bd.
==========================================================================
symbol: l(2)35Be
name: lethal (2) 35Be
UID: FBgn0001975
references:
cytology: 35B4--35B4
cytology_data: Left limit from inclusion within Df(2L)TE35BC-4 (FBrf0038053)
cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544)
ems_allele:
l(2)35Be1
l(2)35Be2
l(2)35Be3
l(2)35Be4
l(2)35Be5
l(2)35Be6
l(2)35Be7
phenotypic_class: vital.
JR_notes: Excision of k08808=l(2)35Bc indicates gene order is 35Bb, 35Bf,
35Be, 35Bc, 35Bd.
===========================================================================
symbol: l(2)35Bc
name: lethal (2) 35Bc
UID: FBgn0001973
references:
cytology: 35B4--35B4
cytology_data: Left limit from inclusion within Df(2L)TE35BC-4 (FBrf0038053)
cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544)
ems_allele:
l(2)35Bc1
l(2)35Bc2
l(2)35Bc3
l(2)35Bc4
l(2)35Bc5
l(2)35Bc6
l(2)35Bc7
l(2)35Bc8
P_element_allele:
l(2)35Bck08808 sequenced
phenotypic_class: vital.
SM_notes: yoyo is in intron of l(2)35Bb; P sequences map to yoyo LTRs
(therefore nested in 35Bb)..
The following P-elements match the sequence of the yoyo LTR but some may be
from other sites:
l(3)06264, l(2)01092, EP(x)1031, l(2)rH280, l(2)k00611, EP(2)0533,
EP(3)0396, EP(x)1102, l(3)j2D5, l(3)rL061
JR_notes: Of 84 viable and 38 lethal excisions of k08808, 3 are deletions:
1 mutant for 35Be and 35Bc, 2 mutant for 35Bc and 35Bd.
This suggests order is 35Bb, 35Bf, 35Be, 35Bc, 35Bd. PZ06264 is a 2nd site
insertion.
===========================================================================
\+symbol:  BG:DS01219 .1
\+formal_name:  BG:DS01219 .1
genefinder: 40/9
genscan: 53(2 spans)/37(1 span)(DS01219)
product:
match_to: SP P34298 e-11 W
EST: LD16050.5'; LD16050.3'; LD13118.5'; LD13118.3'; LD14488.5';
LD17401.5'; LD27791.5'
P1: DS01219, DS00929
direction: -
SM_notes: Translation from full-length LD16050 3' on DS01219 (166-1993),
5' on DS00929 (1-165). k11524p (l(2)35Bb) inserted at 5037 of DS00929,
ESTs from
1533-1359 of DS00929, so could be l(2)35Bb.
===========================================================================
\+symbol:  BG:DS00929 .16
\+formal_name:  BG:DS01219 .16
genefinder:
genscan: 71
product:
match_to:
EST:
P1: DS00929
direction: +
SM_notes: Translation from 5' edited Genscan (missing 5' end?). Good bet
for l(2)35Bb because P element k11524p maps to 5037 of
DS00929 and one ORF of genscan prediction is 4992-5160.
JR_notes: Could also be l(2)35Bf.
===========================================================================
\+symbol:  BG:DS00929 .1
\+formal_name:  BG:DS00929 .1
genefinder: 21
genscan: 49
product:
match_to: GB AA221255 e-32 M (Mus EST)
match_to: GB AA245336 e-32 M (Mus EST)
match_to: GB AA166258 e-32 M (Mus EST)
match_to: GB AA25934 e-27 H (Hum EST)
match_to: GB AA004508 e-10 H (Hum EST)
EST:
P1: DS00929
direction: +
SM_notes: Translation from Genscan. Could be l(2)35Bf or l(2)35Be.
==========================================================================
\+symbol:  BG:DS00929 .2
\+formal_name:  BG:DS00929 .2
genefinder: 43
genscan: 75
product: ankyrin-like
match_to: GB AA200445 e-17 M (Mus EST)
match_to: GB AA200439 e-17 M (Mus EST)
match_to: TR Q19822 e-14 W
match_to: SP P16157 e-10 H
match_to: TR Q24241 e-7 D
EST: LD17234.5'; LD17234.3'
P1: DS00929
direction: -
SM_notes: Translation from full-length LD17234. Could be l(2)35Bf,
l(2)35Be, or l(2)35Bc.
===========================================================================
\+symbol:  BG:DS00929 .3
\+formal_name:  BG:DS00929 .3
genefinder: 44
genscan: 70
product: TATA-binding protein associated phosphoprotein
match_to: SP Q01658 e-33 H
match_to: GB M97388 e-31 H
match_to: GB AA413894 e-31 M (Mus EST)
match_to: TR E1246915 e-19 W
match_to: SP P49592 e-17 A
match_to: TR Q92317 e-10 Y
match_to: YPD 1666487 e-16 Y
EST:
P1: DS00929
direction: +
SM_notes: Translation from Genscan. Could be l(2)35Be or l(2)35Bc.
==========================================================================
\+symbol:  BG:DS00929 .4
\+formal_name:  BG:DS00929 .4
genefinder: 29
genscan: 62
product:
match_to: SP P53215 e-56 Y
match_to: GB Z72809 e-55 Y
match_to: GB T04261 e-29 A
match_to: GB AA450700 e-23 M (Mus EST)
match_to: GB W77781 e-7 H (Hum EST)
EST:
P1: DS00929
direction: -
SM_notes: Translation from Genscan. Could be l(2)35Bc.
===========================================================================
\+symbol: l(2)35Bd
\+formal_name:  BG:DS00929 .5
name: lethal (2) 35Bd
UID: FBgn0001974
references:
cytology: 35B4--35B4
cytology_data: Left limit from inclusion within Df(2L)AntpCtxrv1
(FBrf0092813)
cytology_data: Right limit from inclusion within Df(2L)b84a3 (FBrf0055544)
genefinder: 49
genscan: 684*(2 spans)
product: mRNA cap methyltransferase
match_to: TR D1024575 e-72 H
match_to: SP P32783 e-24 Y
match_to: GB L12000 e-22 Y
match_to: GB Z81038 e-11 W
match_to: GB T21843 e-8 A
EST: LD09819.3'; LD09819.5'; LD27566.5'; LD02165.5'; LD07429.5';
LD10977.5'; LD13245.5'; LD13885.5'; LD19803.5'; LD21076.5'; LD21952.5';
LD22017.5'; LD26541.5'; LD26968.5'; LD27714.5'
P1: DS00929
direction: +
ems_allele:
l(2)35Bd1
l(2)35Bd2
l(2)35Bd3
l(2)35Bd4
l(2)35Bd5
l(2)35Bd6
P_element_allele:
l(2)35Bd10408 sequenced
aberration_associated_allele:
l(2)35BdCtx (Tp(3;2)AntpCtx)
phenotypic_class: vital.
SM_notes: Translation from full-length LD09819. l(2)35Bd 17448-19229
(ESTs), l(2)10408 at ~17507 (plasmid rescue).
===========================================================================
\+symbol:  BG:DS00929 .6
\+formal_name:  BG:DS00929 .6
genefinder: 8/31
genscan: 684*(16 spans)
product: GABA receptor
match_to: TR O08621 e-139 O (rat)
match_to: GB Y10370 e-135 O (rat)
match_to: GB W48985 e-30 M (Mus EST)
match_to: GB AA036134 e-12 M (Mus EST)
match_to: GB X90543 e-18 H (Hum EST)
match_to: TR Q23442 e-15 W
match_to: GB U58748 e-9 W
EST:
P1: DS00929
direction: +
SM_notes: Translation from 5' and 3' edited Genscan (missing 5' end?).
==========================================================================
\+symbol:  BG:DS00929 .7
\+formal_name:  BG:DS00929 .7
genefinder:
genscan:
product: ficolin
match_to: SP P21520 e-23 D
match_to: TR O18546 e-30 O (bloodfluke planorb)
match_to: TR D1026054 e-28 M
match_to: TR Q28763 e-27 H
match_to: TR O17043 e-7 W
EST:
P1: DS00929
direction: -
SM_notes: Translation from 3' edited BLASTX homology to GenBank P21520.
==========================================================================
\+symbol:  BG:DS00929 .8
\+formal_name:  BG:DS00929 .8
genefinder: 66
genscan: 684*(4 spans)
product: yellow-like
match_to: SP P09957 e-74 D
match_to: TR O18330 e-21 O (honey bee)
EST:
P1: DS00929
direction: +
SM_notes: Translation from 5' edited Genscan.
==========================================================================
\+symbol: l(2)35Bg
\+formal_name:  BG:DS00929 .9
synonym: anon-35Ba
name: lethal (2) 35Bg
UID: FBgn0001977
UID: FBgn0015867
references:
FBrf0055545 == Schweisguth and Posakony, 1992, Cell 69: 1199--1212
cytology: 35B10--35B10
cytology_data: Left limit from non-inclusion within Df(2L)b80k (FBrf0092813)
cytology_data: Right limit from inclusion within Df(2L)ARR1 (FBrf0038053)
ems_allele:
l(2)35Bg1
l(2)35Bg2
PM_dysgenesis_allele:
l(2)35BgPI2
P_element_allele:
k10011 sequenced (semilethal)
phenotypic_class: vital.
genefinder: 41
genscan: 47
product:
match_to: TR G3252826 e-14 H
match_to: YPD YKR071C e-9 Y
match_to: GB AA289143 e-7 M (Mus EST)
match_to: SP P41847 e-7 W
EST: GM08660.5'; GM08660.3';GM10279.5'; LD23249.5'; LD32407.5'
P1: DS00929
direction: -
SM_notes: Translation from full-length LD32407. cDNA overlaps  BG:DS00929 .8
but on opposite strand--does this mean  BG:DS00929 .8 not real gene?
l(2)35Bg 46305-43777(ESTs), l(2)k10011 inserted 46297 DS00929.
==========================================================================
\+symbol: Su(H)
\+formal_name:  BG:DS00929 .10
synonym: l(2)35Bh
name: Suppressor of Hairless
UID: FBgn0004837
references:
FBrf0054340 == Furukawa et al., 1991, J. Biol. Chem. 266: 23334--23340
FBrf0055544 == Furukawa et al., 1992, Cell 69: 1191--1197
FBrf0079374 == Schweisguth et al., 1994, Dev. Biol. 166(2): 812--814
FBrf0079375 == Schweisguth, 1995, Development 121(6): 1875--1884
FBrf0068637 == Posakony, 1994, Cell 76(3): 415--418
FBrf0074389 == Schweisguth and Posakony, 1994, Development 120(6):
1433--1441
FBrf0055545 == Schweisguth and Posakony, 1992, Cell 69: 1199--1212
FBrf0084115 == Lecourtois and Schweisguth, 1995, Genes Dev. 9(21):
2598--2608
cytology: 35B10--35B10
cytology_data: Left limit from non-inclusion within Df(2L)b80k (FBrf0092813)
cytology_data: Right limit from inclusion within Df(2L)ARR1 (FBrf0038053)
product: DNA-binding-protein
genefinder: 80
genscan: 188
match_to: GB M81871 e-175 M
match_to: GB X17459 e-175 M
match_to: SP P31266 e-176 M
match_to: SP Q06330 e-158 H
match_to: GB L34543 e-157 H
match_to: GB L34544 e-157 H
match_to: TR Q27427 e-107 W
match_to: GB U49794 e-98 W
match_to: YPD 825569 e-10 Y
EST: LD17227.5'; GM10826.5'; LD22806.5'; LD24729.5'
P1: DS00929
direction: +
homology: species == Mus; gene == Igkrsbp; MGD: MRK-11327
homology: species == Homo sapiens; gene == IGKJRB; GDB: 138293; OMIM:
147183 MEDLINE: 94010923
homology: species == Homo sapiens; gene == IMAGE: 32996; EMBL: R19314; DRES: 55
 cDNA_sequence:X58393 ; g10957
 cDNA_sequence:M94383 ; g158515
 pr_sequence_SwissProt:P28159 
 pr_sequence_PIR:A41585 
 pr_sequence_PIR:A42770 
spontaneous_allele:
Su(H)1
Su(H)2
ems_allele:
Su(H)3
Su(H)4
Su(H)5
Su(H)6
Su(H)7
Su(H)9
Su(H)AM1
Su(H)10
Su(H)11
Su(H)16
Su(H)IB115
Su(H)O5
Su(H)T4
Su(H)eBC11
Su(H)sA21
Su(H)sK2
Su(H)sO10
Su(H)E86
tem_allele:
Su(H)8
PM_dysgenesis_allele:
Su(H)12
Su(H)13
Su(H)14
Su(H)15
P{X6}Su(H)M28=Su(H)1356
P_element_allele:
k07904 sequenced
P_element_derivative_allele:
Su(H)rv1
misc_allele:
Su(H)E(H)
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank M94383.
===========================================================================
\+symbol: ck
\+formal_name:  BG:DS00929 .11
name: crinkled
synonym: Mhc35BC; UID: FBgn0015260;
synonym: anon-35Bb
UID: FBgn0000317
references:
FBrf0083719 == Agrawal et al., 1995, Dev. Biol. 172(1): 218--229
FBrf0054380 == Chen et al., 1991, J. Cell Biol. 115(3/2): 330a
FBrf0089920 == Wright and Jackson, 1996, Trends Genet. 12(6): 206--209
FBrf0055545 == Schweisguth and Posakony, 1992, Cell 69: 1199--1212
cytology: 35B10+--35B10+
cytology_data: Left limit from inclusion within Df(2L)TE35BC-3 (FBrf0038047)
cytology_data: Right limit from inclusion within Df(2L)TE35BC-7 (FBrf0055544)
product: myosin VIIA
genefinder: 179
genscan: 630
match_to: GB U39226 0 H
match_to: GB U81453 0 M
match_to: TR P91443 0 W
match_to: GB U80848 0 W
match_to: TR G3142302 e-128 A
match_to: SP P19524 e-112 Y
match_to: GB Z75234 e-112 Y
EST: LD10736.3'; LD10736.5'; LD14917.5'; LD14874.5'
P1: DS00929
direction: -
spontaneous_allele:
ck1 note that the existing ck1 allele is l(2)35Fb
ems_allele:
ck2
ck3
ck4
ck5
ck6
ck7
ck8
ck9
ck10
ck11
ck12
ck13
ck14
ck15
ck16
ck17
ckA11
ckGJ2
P_element_allele:
ck07130 sequenced
EP2051 sequenced
aberration_associated_allele:
ckH67 (T(2;3)H67)
misc_allele:
ckIK3
TE_insert_allele:
ckTE35BC (TE36)
TE36 derivatives
phenotypic_notes: cell polarity gene; affects denticle belts, microchaetae etc.
phenotypic_class: visible; non_vital.
SM_notes: Translation from alignment of cDNA from D. Kiehart (unfinished).
PZ07130 at nt 65322, first exon of Kiehart's cDNA 65294-65143.
EP2051 at 62404 of DS00929.
===========================================================================
\+symbol: TfIIS
\+formal_name:  BG:DS00929 .12
name: RNA polymerase II elongation factor
synonym: l(2)35Cf
synonym: DmS2
UID: FBgn0010422
UID: FBgn0001982 (l(2)35Cf)
product: RNA-polymerase-II-elongation-factor
motifs: PS00466 == TFIIS zinc ribbon domain signature.
genefinder: 69
genscan: 128
match_to: TR E1309841 e-62 M
match_to: TR Q15560 e-61 H
match_to: SP P52652 e-45 W
match_to: YPD 1322528 e-28 Y
EST: LD32510.5'; LD34766.5'; LD33310.5'; LD15545.5'; GM02906.5';
GM03078.5'; GM04006.5'; GM09514.5'; LD18436.5'
P1: DS00929
direction: -
 genomic_sequence:L26091 ; g416355
 cDNA_sequence:X53670 ; g7921
 pr_sequence_PIR:S12106 
 pr_sequence_PIR:S55899 
 pr_sequence_SwissProt:P20232 
references:
cytology: 35C1--35C1
cytology_data: Left limit from inclusion within Df(2L)TE35BC-3 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)64j (FBrf0051973)
PM_dysgenesis_allele:
l(2)35Cf1
l(2)35Cf2
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank L26091.Genomic sequence
has a stop codon in middle of gene--this is
good sequence from 7 reads of 3 different subclones.
Problem sequence: CGGGATTAGC'TAA'CGTGCCGCG
===========================================================================
\+symbol: vas
\+formal_name:  BG:DS00929 .14
name: vasa
synonym: no-relish
synonym: cgt
UID: FBgn0003970
UID: FBgn0004805
references:
FBrf0047652 == Hay et al., 1988, Cell 55: 577--587
FBrf0048768 == Lasko and Ashburner, 1988, Nature 355: 611--617
FBrf0051865 == Lasko and Ashburner, 1990, Genes Dev. 4: 905--921
FBrf0051573 == Hay et al., 1990, Development 109: 425--433
FBrf0052735 == Dorer et al., 1990, Nucleic Acids Res. 18: 5489--5494
FBrf0054956 == de Valoir et al., 1991, Proc. Natl. Acad. Sci. USA. 88:
2113--2117
FBrf0054123 == Schupbach and Wieschaus, 1991, Genetics 129: 1119--1136
cytology: 35C1--35C1
cytology_data: Left limit from inclusion within Df(2L)TE35BC-3 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)A267 (FBrf0048768)
genefinder: 26(DS00929); 27(DS04929)
genscan: 285*(3 spans)(DS00929); 131(DS04929)
match_to: YPD 1430979 e-13(DS00929) Y
match_to: TR O01378 e-122(DS04929) O (silkworm)
match_to: SP Q61496 e-96(DS04929) M
match_to: SP P06634 e-88(DS04929) Y
match_to: TR O15523 e-87(DS04929) H
match_to: SP P34689 e-69(DS04929) W
match_to: TR O22907 e-52(DS04929) A
EST: LD06084.5'; LD12044.5'; LD17083.5'
P1: DS00929, DS04929
direction: +
motifs: PS00039 == DEAD-box subfamily ATP-dependent helicases signature.
homology: species == Caenorhabditis elegans; gene == glh-1
homology: species == Mus; gene == 'Vasa'; EMBL: D14859
 genomic_sequence:X12945 ; g1054723
 genomic_sequence:X12946 
 cDNA_sequence:M23560 ; g158796
 pr_sequence_SwissProt:P09052 
 pr_sequence_TREMBL:Q24582 
 pr_sequence_PIR:A31922 
 pr_sequence_PIR:S01676 
ems_allele:
vas1
vas2
vas3
vas4
vas5
vas6
vasAQB3
vasD5
vasHE1
vasPW72
vasQS17
vasRG53
fs(2)ltoRJ36RJ36
vasPH165
misc_allele:
vas3F
vas4C
vasAS
vasKD
vas88c25
P_element_allele:
vasLYG2
EP(2)0812 sequenced
k07233 sequenced
PM_dysgenesis_allele:
vasP808
phenotypic_class: female_sterile; non_vital.
JR_notes: identity of vasa and courgette based on our complementation data
and those of Montell.
SM_notes: Translation of 5' from alignment of GenBank X12945 on DS00929,
but with LD06084.5' at 5' end. Translation of 3' from alignment of GenBank
M23560 on DS04929.
k07233 maps to 74616 of DS00929. EP0812 maps to 72346, 2.3kb upstream.
===========================================================================
\+symbol: vig
\+formal_name:  BG:DS00929 .13
name: vasa intronic gene
UID: FBgn0024183
genefinder: 81
genscan: 248
product:
match_to: YPD 927699 e-8 Y
match_to: TR O24106 e-7 O (tobacco)
EST: LD07162.5'; LD07162.3'; HL01210.5'; LD20406.5';
P1: DS00929
direction: -
Nested_in: vasa
MA_notes: This is vig (vasa intronic gene) of Kevin Edwards.
P-elements (EP(2)0812, k07233) that map within vig behave genetically as vasa
alleles.
SM_notes: Translation from full-length LD07162.
===========================================================================
\+symbol:  BG:DS00929 .15
\+formal_name:  BG:DS00929 .15
genefinder:
genscan: 285*(2 spans)
product:
match_to:
EST:
P1: DS00929
direction: +
Nested_in: vasa
SM_notes: Translation from 5' edited Genscan (missing 5' end?).
Paul Lasko's ORF within 3rd vasa intron. Paul's coordinates are
76407-77600 and 77894-79528 on the same strand as vasa.
===========================================================================
\+symbol:  BG:DS04929 .1
\+formal_name:  BG:DS04929 .1
genefinder: (11)/68
genscan: 302
product:
match_to: GB R18707 e-11 H (Hum EST)
match_to: GB W71312 e-17 M (Mus EST)
EST:
P1: DS04929
direction: +
SM_notes: Translation from Genscan. This is Hawley's Axs-like gene.
JR_notes: Hawley says in b87e25, but not in A267.
==========================================================================
\+symbol:  BG:DS04929 .3
\+formal_name:  BG:DS04929 .3
genefinder: 54
genscan: 461* (3 spans)
product: Zinc-finger protein (snail-like)
match_to: TR G3098097 e-35 D
match_to: SP P51814 e-49 H
match_to: TR Q62512 e-49 M
match_to: GB M92443 e-46 H
match_to: GB D10627 e-46 M
match_to: SP P47043 e-24 Y
match_to: GB Z49331 e-24 Y
match_to: TR Q22874 e-27 W
match_to: TR O02265 e-27 W
EST:
P1: DS04929
direction: +
SM_notes: Translation from 3' edited Genscan.
==========================================================================
\+symbol: stc
\+formal_name:  BG:DS04929 .4
name: shuttle craft
synonym: l(2)35Cb
UID: FBgn0001978
references:
FBrf0085996 == Stroumbakis et al., 1996, Molec. Cell. Biol. 16(1): 192--201
FBrf0086298 == Aasland et al., 1995, Trends Biochem. Sci. 20: 56--59
cytology: 35C1--35C1
cytology_data: Left limit from inclusion within Df(2L)TE35BC-3 (FBrf0038047)
cytology_data: Right limit from inclusion within Df(2L)TE35B-5 (FBrf0092813)
genefinder: 114
genscan: 461*(6 spans)
product: DNA-binding-protein-(single-stranded)
match_to: TR Q18034 e-136 W
match_to: SP Q12986 e-92 H
match_to: GB U15306 e-90 H
match_to: YPD 1301855 e-71 Y
match_to: SP P53971 e-69 Y
match_to: GB AA034687 e-9 M (Mus EST)
match_to: GB AB005237 e-35 A
EST: LD08727.5'; LD09946.5'; LD02285.5'; LD08763.5'; LD22726.5';
LD27525.5'; LD32773.5'; LD25467.5'; LD29364.5'; LD25490.5'
P1: DS04929
direction: +
motifs: RD-domain protein.
motifs: Zinc finger, C4HC3 type (PHD finger), protein.
homology: species == Homo sapiens; gene == 'NF-X1'; EMBL: U15306
 cDNA_sequence:U09306 ; g487400
 pr_sequence_SwissProt:P40798 
ems_allele:
stc1
stc2
stc3
stc4
stc5
P_element_allele:
stc05441 sequenced this is aka PZ9
aberration_associated_allele:
stc6 (In(2L)dpps22)
Df(2L)Sco-rv4 hypomorphic
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank U09306. PZ05441 is in
intron of DS04929.3. Only 9bp of sequence from
k11112, which maps to DS07851 by in situ, but by sequence matches many Adh
P1s.
JR_notes: PZ05441 confirmed as stc allele, but k11112 unlikely to be stc
allele. 10 excisions of k11112; all are lethal over stc-.
===========================================================================
\+symbol:  BG:DS03192 .1
\+formal_name:  BG:DS03192 .1
genefinder:
genscan:
tRNAscan-SE: 66
product: transfer  RNA:leu 
match_to:
EST:
P1: DS03192
direction: -
==========================================================================
\+symbol:  BG:DS03192 .3
\+formal_name:  BG:DS03192 .3
genefinder:
genscan:
product:
match_to:
EST: HL02392.5'; HL02392.3'
P1: DS03192
direction: +
SM_notes: Translation from full-length HL02392. No good ORF in HL02392
cDNA, so short.
==========================================================================
\+symbol:  BG:DS03192 .2
\+formal_name:  BG:DS03192 .2
genefinder: 82/(15)
genscan: 301
product: chaoptin_like
match_to: GB M19017 e-57 D
match_to: TR Q18902 e-50 W
match_to: SP O02833 e-28 H
match_to: SP P70389 e-22 M
match_to: YPD 1006714 e-17 Y
match_to: TR Q42371 e-11 A
match_to: TR G3075386 e-11 A
EST:
P1: DS03192
direction: -
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS03192 .4
\+formal_name:  BG:DS03192 .4
genefinder:
genscan:
product:
match_to:
EST: CK01083.5'
P1: DS03192
direction: -
Nested_in:  BG:DS03192 .2
SM_notes: Translation from full-length CK01083. No good ORF so short.
CK01083.3prime sequence doesn't match. No good ORF.
==========================================================================
\+symbol:  BG:DS07295 .1
\+formal_name:  BG:DS07295 .1
genefinder: 35
genscan: 66
product: Zinc transporter
match_to: TR Q62941 e-49 O (rat)
match_to: GB U50927 e-41 O (rat)
match_to: TR Q22541 e-45 W
match_to: TR O35149 e-27 M
match_to: TR P97441 e-39 M
match_to: TR O14863 e-27 H
match_to: TR Q99726 e-35 H
match_to: YPD 1420694 e-10 Y
EST: GM01103.5'; GM01103.3'; GM10990.5'; GM010990.3'; GM02135.5';
GM03441.5'; GM04177.5'; GM07809.5'
P1: DS03192 (was DS07295)
direction: -
SM_notes: Translation from full-length GM01103. Interesting that it is
only in ovary cDNA library.
===========================================================================
\+symbol:  BG:DS07295 .4
\+formal_name:  BG:DS07295 .4
genefinder:
genscan: 76
product:
match_to:
EST:
P1: DS03192 (was DS07295)
direction: +
Nested_in:  BG:DS07295 .1
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS07295 .2
\+formal_name:  BG:DS07295 .2
genefinder: 128
genscan: 261
product:
match_to:
EST:
P1: DS03192 (was DS07295)
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS07295 .3
\+formal_name:  BG:DS07295 .3
genefinder: 60
genscan: 139
product:
match_to: YPD 486581 e-7 Y
match_to: YPD 1323271 e-7 Y
EST: LD09767.5'; LD09767.3'; LD17641.5'; GM09074.5'
P1: DS03192 (was DS07295), (DS05639)
direction: -
SM_notes: Translation from full-length LD09767.
==========================================================================
\+symbol:  BG:DS07295 .5
\+formal_name:  BG:DS07295 .5
genefinder: 26(DS03192)
genscan: 96(DS03192)
product:
match_to:
EST:
P1: DS03192 (was DS07295), DS05639
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS05639 .1
\+formal_name:  BG:DS05639 .1
genefinder: 22(DS03192)/59/26(DS05639)
genscan: 64(DS03192)/205(DS05639)
product:
match_to:
EST:
P1: DS03192 (includes DS07295), DS05639, DS07851
direction: -
SM_notes: Translation from genscan--was formerly 3' end of  BG:DS07851 .11.
==========================================================================
\+symbol:  BG:DS07851 .11
\+formal_name:  BG:DS07851 .11
genefinder: 32(DS07851)
genscan: 349* (2 spans)(DS07851)
product:
match_to:
EST: GH14032.5'
P1: DS05639, DS07851
direction: -
SM_notes: Translation from full-length GH14032 on DS07851.
==========================================================================
symbol: rd
name: reduced
UID: FBgn0003213
references:
FBrf0092806 == Mohler, 1997, Mini-AIR 1997-02
cytology: 35C3+--35C3+
cytology_data: Left limit from inclusion within Df(2L)TE35D-15 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)A215 (FBrf0038050)
spontaneous_allele:
rd1
rds
gamma_ray_allele:
rd4
rd7
rd9
misc_allele:
rdGJ3
phenotypic_notes: bristles short and thin.
phenotypic_class: visible; non_vital.
JR_notes: Rare male recombinants of gftPZ06430 are either rd+, 35Cc+, gft-,
ms(2)35Ci- or rd+, 35Cc-, gft-, ms(2)35Ci+ i.e. we have separated rd
from 35Cc (35Cc is real) and ordered rd, 35Cc and gft (in that order).
===========================================================================
symbol: l(2)35Cc
name: lethal (2) 35Cc
UID: FBgn0001979
references:
cytology: 35C3+--35C3+
cytology_data: Left limit from inclusion within Df(2L)TE35D-15 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)A263 (FBrf0055544)
alleles:
none known; associated with lethality of Df(2L)rd9.
phenotypic_class: vital.
JR_notes: Rare male recombinants of gftPZ06430 are either rd+, 35Cc+, gft-,
ms(2)35Ci- or rd+, 35Cc-, gft-, ms(2)35Ci+ i.e. we have separated rd
from 35Cc (35Cc is real) and ordered rd, 35Cc and gft (in that order).
===========================================================================
\+symbol: gft
\+formal_name:  BG:DS07851 .2
name: guftagu
synonym: l(2)35Cd
UID: FBgn0001980
references:
FBrf0085597 == Mistry et al., 1996, A. Conf. Dros. Res. 37: 352
cytology: 35C3+--35C3+
cytology_data: Left limit from inclusion within Df(2L)TE35D-15 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)A263 (FBrf0038050)
genefinder: 79
genscan: 349*(10 spans)
product: CUL-3 homolog
match_to: SP Q17391 e-152 W
match_to: GB U58085 e-134 W
match_to: TR G3139079 e-176 H
match_to: TR O22770 e-43 A
match_to: SP P53202 e-20 Y
EST: LD10516.3'; LD10516.5'; LD03316.5'; LD03964.5'; LD34096.5'; LD29530.5'
P1: DS07851
direction: -
ems_allele:
gft1
gft2
gft3
gft4
gft5
gft6
gft7
P_element_allele:
gft06430 sequenced
PM_dysgenesis_allele:
gftd577
gamma_induced_allele:
gftGR18
misc_allele:
gftIK1
phenotypic_notes: lethal escapers with unexpanded wings, small eyes.
phenotypic_class: vital.
JR_notes: Rare male recombinants of gftPZ06430 are either rd+, 35Cc+, gft-,
ms(2)35Ci- or rd+, 35Cc-, gft-, ms(2)35Ci+
SM_notes: Translation from full-length LD10516.
===========================================================================
\+symbol:  BG:DS07851 .3
\+formal_name:  BG:DS07851 .3
genefinder: 22
genscan:
product: perchloric acid soluble
match_to: SP P52759 e-17 O (rat)
match_to: SP P52760 e-23 M
match_to: SP P52758 e-22 H
match_to: SP Q10121 e-18 W
match_to: SP P40185 e-10 Y
match_to: SP P40037 e-7 Y
EST: GM01181.3'; GM01181.5'
P1: DS07851
direction: -
SM_notes: Translation from full-length GM01181.
===========================================================================
\+symbol:  BG:DS07851 .4
\+formal_name:  BG:DS07851 .4
genefinder: 22
genscan: 65
product:
match_to:
EST:
P1: DS07851
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS07851 .8
\+formal_name:  BG:DS07851 .8
genefinder: 22
genscan: 59
product:
match_to:
EST:
P1: DS07851
direction: -
SM_notes: Translation from Genscan. maps close to ms(2)02316=ms(2)35Ci
(27661-29308 vs 30208)
JR_notes: ms(2)46AB02316 maps within A263, osp18 and TE35D-6 but not
noc11, nBR129, TE35D-2 or TE35D-21.
Zuker's ms 14-107 maps to the same place i.e. it is ms over A263
(Df(2L)34E5-F1;35C3-5) and osp18.
ms(2)46AB02316 is homozygous male fertile and fertile over ms
14-107, but could be a weak allele of the same gene.
ms 14-107 is homozygous ms.
==========================================================================
\+symbol: ms(2)35Ci
\+formal_name:  BG:DS07851 .10
synonym: 14-107
genefinder:
genscan: (35)
product:
match_to:
EST:
P1: DS07851
direction: -
P_element_allele:
ms(2)35Ci02316
SM_notes: Translation from Genscan. ms(2)02316 maps in intron of gene
prediction (29377-33910 vs 30208)
 BG:DS07851 .8 maps close to ms(2)02316=ms(2)35Ci (27661-29308 vs 30208)
ms(2)02316 maps in intron of  BG:DS07851 .10 gene prediction(29377-33910 vs
30208)
JR_notes: ms(2)46AB02316 maps genetically to the same region as the Zuker
ms 14-107 i.e. it is ms over A263 (Df(2L)34E5-F1;35C3-5) and osp18
ms(2)46AB02316 is homozygous male fertile and fertile over ms
14-107, but could be a weak allele of the same gene.ms 14-107 is homozygous ms.
JR_notes: Zuker EMS male-sterile mapped to gft-esg interval
ms(2)46AB02316 maps within A263, osp18 and TE35D-6 but not
noc11, nBR129, TE35D-2 or TE35D-21.Zuker's ms 14-107 maps to the same place
i.e. it is ms over A263
(Df(2L)34E5-F1;35C3-5) and osp18.
ms(2)46AB02316 is homozygous male fertile and fertile over ms
14-107, but could be a weak allele of the same gene.
ms 14-107 is homozygous ms.
==========================================================================
\+symbol:  BG:DS07851 .5
\+formal_name:  BG:DS07851 .5
genefinder: 31
genscan: 108
product:
match_to: GB AA864782 e-8 H (Homo EST)
match_to: TR Q94547 e-19 D
match_to: TR Q10923 e-12 W
match_to: YPD 1431262 e-7 Y
EST:
P1: DS07851
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS07851 .6
\+formal_name:  BG:DS07851 .6
genefinder: (20)
genscan: 60
product:
match_to:
EST:
P1: DS07851
direction: -
SM_notes: Translation from Genscan.
==========================================================================
symbol: l(2)35Cg
JR_notes: Predicted from deletion o/laps.
==========================================================================
\+symbol: esg
\+formal_name:  BG:DS07851 .7
name: escargot
synonym: l(2)35Ce
synonym: shof
synonym: l(2)k08225
UID: FBgn0001981
references:
FBrf0057128 == Whiteley et al., 1992, Mech. Dev. 36: 117--127
FBrf0055837 == Smith et al., 1992, Development 116(4): 1033--1039
FBrf0058108 == Hayashi et al., 1993, Development 118(1): 105--115
references l(2)k08225:
FBrf0058618 == Torok et al., 1993, Genetics 135(1): 71--80
FBrf0080244 == Mechler, 1994, J. Biosci., Bangalore 19(5): 537--556
cytology: 35C4--35C5
cytology_data: Left limit from inclusion within Df(2L)TE35D-13 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)TE35B-1 (FBrf0091422)
motifs: PS00028 == Zinc finger, C2H2 type, domain.
genefinder: 65
genscan: 158
match_to: TR P97469 e-50 M
match_to: GB U79550 e-49 M
match_to: TR G2832266 e-50 H
match_to: TR E1297902 e-28 W
match_to: SP P47043 e-12 Y
match_to: YPD 1008197 e-17 Y
EST:
P1: DS07851
direction: +
homology: species == Homo sapiens; gene == IMAGE: 198754; EMBL: R95170;
DRES: 51
homology: species == Xenopus laevis; gene == 'XSNA'; SWP: P19382
 cDNA_sequence:M83207 ; g157367
 pr_sequence_SwissProt:P25932 
 pr_sequence_PIR:S33639 
ems_allele:
esg35Ce-1
esg35Ce-2
esg35Ce-3
P_element_allele:
esg05729
esg05730 sequenced
esg07082 sequenced
esgB7-2-22
esgG66
esgM5-4
esgP1
esgP2
esgk00109
esgk00418
esgk00606
esgk01107
esgk01502
esgk02706
esgk02811
k03506
esgk04408
esgk04802
esgk05210
esgk05517
esgk05818
esgk07808
esgk07902
esgk08104
esgk08418
esgk08505
esgk08610
esgk08910
esgk10811 cluster: k10817* in situ & seq at 50C, hit&run
esgk14104 cluster: k14108
esgk14811
esgk15418
esgk15818
esgk16117
PZ06346 sequenced this a second site; PZ06346 per se Stat92E allele
l(2)k08225k08225 sequenced
n(2)k09122 sequenced
n(2)k04509 sequenced
n(2)k06817b sequenced
n(2)k05652 sequenced
n(2)k03802 sequenced
n(2)k04207 sequenced
n(2)k03503 sequenced
n(2)k15310 sequenced
EP(2)0633 sequenced
EP(2)0683 sequenced
EP(2)0684 sequenced
EP(2)2408 sequenced
EP(2)2009 sequenced
EP(2)2159 sequenced
n(2)k02405 sequenced
l(2)k07018 sequenced
l(2)k06211
k03012
k17032
P_element_derivative_allele:
esgL2
esgL3
esgL6
esgL7
PM_dysgenesis_allele:
esg148
esg80
esg94
esgflg
aberration_associated_allele:
esgGW2 (Df(2L)TE35D-2)
esgGW13 (Df(2L)TE35D-13)
esgGW21 (Df(2L)TE35D-21)
esgdgl (T(Y;2)J165)
k15711 sequenced this is a deletion 35Bb-esg, hypomorphic esg
phenotypic_class: vital.
phenotypic_notes: l(2)k08225 = neoplastic brain phenotype, vital.
JR_notes: k15310, k09122 and k03503 have no esg phenotype - they are viable
& fertile - over esg-
JR_notes: k08225 viable and fertile with A48, b84a7 and r10 (reduced female
fert with A48). Worrying because Torok et al states: P-element excision
demonstrates the insertion to be the cause of lethality.
SM_notes: Translation from alignment of GenBank M83207.
==========================================================================
\+symbol:  BG:DS03023 .4
\+formal_name:  BG:DS03023 .4
genefinder:
genscan: 194
product:
match_to:
EST:
P1: DS03023
direction: -
SM_notes: Translation from Genscan.
===========================================================================
\+symbol: wor
\+formal_name:  BG:DS03023 .1
name: lethal (2) 35Da
name: worniu
synonym: l(2)35Da
synonym: schnecke
UID: FBgn0001983
references:
cytology: 35D1--35D1
cytology_data: Left limit from inclusion within Df(2L)TE35D-2 (FBrf0051973)
cytology_data: Right limit from complementation mapping against Tp(2;2)Sco
(citation unavailable)
product: Zinc-finger protein
genefinder: 73
genscan: 147
match_to: GB M83207 e-51 D
match_to: SP P25932 e-67 D
match_to: TR G2832266 e-50 H
match_to: TR P97469 e-50 M
match_to: TR E1297902 e-28 W
match_to: SP P47043 e-12 Y
match_to: YPD 1008197 e-15 Y
EST:
P1: DS03023
direction: -
ems_allele:
l(2)35Da1
l(2)35Da2
l(2)35Da3
l(2)35Da4
misc_allele:
l(2)35DaAB108
l(2)35DaAB114
l(2)35DaAB48
l(2)35DaAS79
phenotypic_notes: disrupted polarity in larval cuticle belts.
phenotypic_class: vital.
SM_notes: Translation from alignment of cDNA sequence from T. Ip (was
called zfp).
===========================================================================
symbol: l(2)35Ch
synonym: l(2)
phenotypic_class: lethal
JR_notes: No alleles; overlapping deletion phenotype; predicted between
l(2)35Da and sna.
===========================================================================
\+symbol:  BG:DS03023 .2
\+formal_name:  BG:DS03023 .2
genefinder: 30
genscan: 127
product:
match_to: LD26668.5' e-8
match_to: TR E1246803 e-53 W
match_to: SP Q04371 e-22 Y
match_to: GB AA450460 e-15 M (Mus EST)
match_to: GB AA223779 e-7 H (Hum EST)
EST:
P1: DS03023
direction: +
SM_notes: Translation from Genscan.
==========================================================================
\+symbol: sna
\+formal_name:  BG:DS01845 .1
name: snail
synonym: l(2)35Db
UID: FBgn0003448
references:
FBrf0053832 == Alberga et al., 1991, Development 111: 983--992
FBrf0047066 == Boulay et al., 1987, Nature 330: 395--398
FBrf0064312 == Boulay, 1988, Ph.D. Thesis, Louis Pasteur, Strasbourg.,
107pp.
FBrf0056115 == Ip et al., 1992, Genes Dev. 6: 1728--1739
FBrf0057499 == Sommer et al., 1992, Proc. natn. Acad. Sci. USA. 89(22):
10782--10786
FBrf0046065 == Carroll et al., 1987, Development 99: 327--332
FBrf0063478 == Grau et al., 1984, Genetics 108: 347--360
FBrf0057526 == Kasai et al., 1992, Proc. natn. Acad. Sci. USA. 89:
3414--3418
FBrf0051581 == Leptin and Grunewald, 1990, Development 110(1): 73--84
FBrf0054033 == Leptin, 1991, Genes Dev. 5: 1568--1576
FBrf0054034 == Rao et al., 1991, Genes Dev. 5: 1577--1588
FBrf0051595 == Sargent and Bennett, 1990, Development 109: 967--973
cytology: 35D1--35D2
cytology_data: Left limit from inclusion within Df(2L)Scorv16
(FBrf0039455)
cytology_data: Right limit from inclusion within Df(2L)b80e4 (FBrf0051973)
product: transcription-factor
product: DNA-binding-protein
genefinder: 73
genscan: 136 (2 spans)
match_to: TR O16139 e-55 O (sea urchin)
match_to: TR P97469 e-51 M
match_to: GB U79550 e-50 M
match_to: TR G2832266 e-51 H
match_to: TR E1297902 e-31 W
match_to: SP P47043 e-15 Y
match_to: YPD 1008197 e-15 Y
EST:
P1: DS01845
direction: -
motifs: PS00028 == Zinc finger, C2H2 type, domain.
homology: species == Mus; gene == Sna; MGD: MRK-14460 MEDLINE: 93130772
 cDNA_sequence:Y00288 ; g8630
 pr_SwissProt:P08044 
 pr_sequence_PIR:S06222 
 pr_sequence_PIR:C46363 
ems_allele:
sna1
sna2
sna3
sna4
sna9
sna10
sna11
sna12
sna13
sna14
sna15
sna16
sna17
sna18
X_ray_allele:
sna5
sna6
sna8
sna19
sna20
snaS1
misc_allele:
snaAM15
snary40
aberration_associated_allele:
sna7 (T(2;3)sna7)
snaH50 (T(2;3)H50)
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank Y00288.
===========================================================================
\+symbol: Tim17
\+formal_name:  BG:DS01845 .2
name: Translocase inner membrane 17
references:
FBrf0090402
products: preprotein translocase of the inner mitochondrial membrane
genefinder: (19)
genscan: 80
match_to: LD02976.5' e-54 D
match_to: SP Q99595 e-45 H
match_to: GB X97544 e-43 H
match_to: GB AA014040 e-40 M (Mus EST)
match_to: YPD 1015553 e-32 Y
match_to: SP P39515 e-31 Y
match_to: TR G2702415 e-30 W
match_to: GB T45278 e-21 A
match_to: CK01513.3' e-26 D
EST:
P1: DS01845
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR products from GH(4)
and LP(2) libraries.
===========================================================================
\+symbol: lace
\+formal_name:  BG:DS01845 .3
name: lace
synonym: l(2)35Dc
UID: FBgn0002524
references:
FBrf0064312 == Boulay, 1988, Ph.D. Thesis, Louis Pasteur, Strasbourg.,
107pp.
cytology: 35D3--35D3
cytology_data: Left limit from in situ hybridisation (FBrf0067338)
cytology_data: Right limit from complementation mapping against T(Y;2)b8
(citation unavailable)
genefinder: 11/67
genscan: 147
product: serine palmitoyl transferase
match_to: GB X95642 e-128 M
match_to: TR P97363 e-130 M
match_to: TR O15270 e-129 H
match_to: TR D1026382 e-129 H
match_to: TR Q20375 e-109 W
match_to: YPD 798913 e-97 Y
match_to: SP P40970 e-90 Y
EST: LD17449.5'; LD17449.3'
P1: DS01845
direction: +
spontaneous_allele:
lace1
ems_allele:
lace2
lace4
lace5
lace6
lace7
lace8
lace9
lace10
lace11
lace12
lace14
lace15
lace16
lace17
P_element_allele:
lacek00706
lacek02303
lacek05305 sequenced
lacek07501
lacek08208
lacek11309
misc_allele:
laceIRX6
lacea2
aberration_associated_allele:
lace3 (T(Y;2)b8)
phenotypic_notes: weak alleles escape with supernumerary wing vein fragments.
phenotypic_class: vital.
SM_notes: Translation from full-length LD17449.
==========================================================================
\+symbol:  BG:DS04862 .2
\+formal_name:  BG:DS04862 .2
genefinder:
genscan: 66
product:
match_to:
EST:
P1: DS04862
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR products from GM(1)
and GH(1) libraries.
==========================================================================
\+symbol: kek3
\+formal_name:  BG:DS04862 .1
genefinder: 110
genscan: 252
product: kek1-like
match_to: GB U42767 e-25 D
match_to: TR P91643 e-68 D
match_to: TR P70193 e-17 M
match_to: TR O15335 e-14ry H
match_to: TR O16781 e-9 W
EST: GH12215.5', GH14053.5'
P1: DS04862
direction: +
JR_notes: From Jean-Marc's data Df(2L)75c removes this gene. Duffy is
going to make 75c, EGFR- recombinants to see whether (like kek1) kek3
rescues/suppresses the various EGFR phenotypes.
SM_notes: Translation 5' from Genscan/genefinder, middle and 3' from full
sequence of GH12215. This clone not full-length? 5' end has kek homology.
==========================================================================
\+symbol:  BG:BACR44L22 .1
\+formal_name:  BG:BACR44L22 .1
genefinder: 25
genscan: 64
product: peptidase family M12A (Zn metalloprotease); astacin subfamily
match_to: SP P55112 e-33 W
match_to: SP Q16820 e-30 H
match_to: SP Q61847 e-26 M
EST:
P1: BACR44L22
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR products from GH(2)
and LP(5) libraries.
==========================================================================
\+symbol:  BG:BACR44L22 .8
\+formal_name:  BG:BACR44L22 .8
genefinder:
genscan: 110* (2 spans)
product: peptidase family M12A (Zn metalloprotease); astacin subfamily
match_to: SP P55112 e-26 W
match_to: SP Q16820 e-19 H
match_to: SP P55113 e-19 W
match_to: TR G238981 e-19 H
match_to: SP P28825 e-15 M
EST:
P1: BACR44L22
direction: -
SM_notes: Translation from edited Genscan (two spans). Kerrie reports PCR
product from GH(1) library.
==========================================================================
\+symbol:  BG:BACR44L22 .2
\+formal_name:  BG:BACR44L22 .2
genefinder: 23
genscan: 110* (2 spans)
product: peptidase family M12A (Zn metalloprotease); astacin subfamily
match_to: SP P55112 e-31 W
match_to: SP Q16820 e-30 H
match_to: SP P55113 e-19 W
match_to: TR G238981 e-24 H
match_to: SP P28826 e-23 M (rat)
EST:
P1: BACR44L22
direction: -
SM_notes: Translation from edited Genscan (two spans). Kerrie reports PCR
products from GH(2) and LP(2) libraries.
==========================================================================
\+symbol:  BG:BACR44L22 .3
\+formal_name:  BG:BACR44L22 .3
genefinder:
genscan: 53
product: peptidase family M12A (Zn metalloprotease); astacin subfamily
match_to: SP P55112 e-33 W
match_to: TR G238981 e-27 H
match_to: SP Q61847 e-23 M
EST:
P1: BACR44L22
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR products from GH(1)
and LP(1) libraries.
==========================================================================
\+symbol:  BG:BACR44L22 .4
\+formal_name:  BG:BACR44L22 .4
genefinder:
genscan: (29)
product: peptidase family M12A (Zn metalloprotease); astacin subfamily
match_to: SP P55112 e-28 W
match_to: TR G238981 e-25 H
match_to: SP P28825 e-22 M
EST:
P1: BACR44L22
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR product from GH(1)
library.
==========================================================================
\+symbol:  BG:BACR44L22 .5
\+formal_name:  BG:BACR44L22 .5
genefinder:
genscan: 51
product:
match_to:
EST:
P1: BACR44L22
direction: -
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:BACR44L22 .6
\+formal_name:  BG:BACR44L22 .6
genefinder: 25
genscan: 59 (2 spans)
product: peptidase family M12A (Zn metalloprotease); astacin subfamily
match_to: SP P55112 e-35 W
match_to: TR Q18439 e-23 W
match_to: TR G238981 e-25 H
match_to: SP Q16820 e-23 H
match_to: SP Q61847 e-21 M
EST:
P1: BACR44L22
direction: +
SM_notes: Translation from 5' edited Genscan and homology.
==========================================================================
\+symbol:  BG:DS07108 .4
\+formal_name:  BG:DS07108 .4
genefinder: 46(BACR44L22)/20(DS07108)
genscan: 155(BACR44L22)/71(DS07108)
product:
match_to: SP P02750 e-9 H
match_to: TR D1033423 e-8 M (rat)
match_to: TR G2668616 e-7 W
EST: LP11031.5', LP08921.5'
P1: BACR44L22, DS07108
direction: +
SM_notes: Translation from Genscan at 5' and complete sequence of LP11031
at 3' (clone not full-length?).
==========================================================================
\+symbol:  BG:DS07108 .2
\+formal_name:  BG:DS07108 .2
genefinder: 128
genscan: 309
product: DHP-sensitive Ca-channel
match_to: TR O08532 e-51 M
match_to: TR O08533 e-51 M
match_to: TR O08534 e-51 M
match_to: TR O08535 e-51 M
match_to: TR O08536 e-51 M
match_to: SP P54289 e-51 H
match_to: TR G2781441 e-53 H
match_to: SP P34374 e-24 W
EST:
P1: DS07108
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR products from LD
A8-F8 (2) library.
==========================================================================
\+symbol:  BG:DS07108 .1
\+formal_name:  BG:DS07108 .1
genefinder:
genscan: 75
product: serine protease
match_to: TR P91817 e-40 O (horseshoe crab)
match_to: GB D87214 e-39 O (horseshoe crab)
match_to: SP P21845 e-25 M
match_to: SP Q05319 e-25 D
match_to: SP P40313 e-23 H
match_to: TR Q17800 e-19 W
EST:
P1: DS07108
direction: +
JR_notes: Jean-Marc Reichhart has been assaying putative overlapping
deletions in the lace-CycE
interval for the absence of the serine proteases (DS07108.1 and .5). He
has found that only 2 combinations Df(2L)75c/TE35D-17 and 75c/TE35D-19
remove these genes. None of the other 9 coming in from the left remove
them and neither does the one other coming in from the right (TE35D-3).
(This fits with the lace-DS07108.1 and DS07108.5-CycE distances.)
SM_notes: Translation from Genscan.
==========================================================================
\+symbol:  BG:DS07108 .5
\+formal_name:  BG:DS07108 .5
P_element_allele:
PZ09259 sequenced
genefinder:
genscan: 25
product: serine protease
match_to: TR P91817 e-34 O (horseshoe crab)
match_to: GB D87214 e-33 O (horseshoe crab)
match_to: TR E1319203 e-25 M
match_to: SP P05981 e-22 H
EST:
P1: DS07108
direction: +
SM_notes: Translation from Genscan.
PZ09259 maps 3'(50257-50281) to this gene(37545-38529); allele ?
==========================================================================
\+symbol: CycE
\+formal_name:  BG:DS07108 .3
name: Cyclin E
synonym: l(2)35Dd
UID: FBgn0010382
references:
FBrf0080145 == Kania et al., 1995, Genetics 139(4): 1663--1678
FBrf0073016 == Edgar, 1994, Curr. Biol. 4(6): 522--524
FBrf0077697 == Orr-Weaver, 1994, Trends Genet. 10(9): 321--327
FBrf0065548 == Richardson et al., 1993, Development 119(3): 673--690
FBrf0068557 == Knoblich et al., 1994, Cell 77(1): 107--120
FBrf0073011 == Duronio and O'Farrell, 1994, Development 120(6): 1503--1515
FBrf0073015 == Edgar et al., 1994, Development 120(11): 3131--3143
FBrf0081968 == Duronio and O'Farrell, 1995, Genes Dev. 9(12): 1456--1468
FBrf0082560 == Sauer et al., 1995, Genes Dev. 9(11): 1327--1339
FBrf0084309 == Richardson et al., 1995, Development 121(10): 3371--3379
FBrf0073016 == Edgar, 1994, Curr. Biol. 4(6): 522--524
FBrf0084488 == Weigmann and Lehner, 1995, Development 121(11): 3713--3721
FBrf0077261 == Finley and Brent, 1994, Proc. natn. Acad. Sci. USA.
91(26): 12980--12984
FBrf0091052 == Edgar and Lehner, 1996, Science 274(5293): 1646--1652
FBrf0092831 == Follette, , Cell 88: 309--314
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)el80f1 (FBrf0039455)
cytology_data: Right limit from inclusion within Df(2L)A377 (FBrf0038050)
genefinder: 94
genscan: 193/(33)
product: cyclin
match_to: SP P47794 e-60 O (zebrafish)
match_to: SP P24864 e-57 H
match_to: TR Q61457 e-57 M
match_to: TR O01501 e-30 W
match_to: SP P30283 e-18 Y
EST: LD17578.5'; LD12856.5'; LD13027.5'; LD15627.5'; LD02508.5';
LD16315.5'; LD16315.5'; LD19554.5'; LD22682.5'; LD24885.5'; LD26520.5';
LD27646.5'; LD29877.5'; LD29878.5'
P1: DS07108, DS09217
direction: -
motifs: Cyclins signature protein.
homology: species == Homo sapiens; gene == CCNE; GDB: 128967; OMIM: 123837
 cDNA_sequence:X75026 ; g429166
 cDNA_sequence:X75027 ; g429168
 pr_sequence_SwissProt:P54733 
 pr_sequence_TREMBL:Q24479 
 pr_sequence_PIR:S41755 
 pr_sequence_PIR:S41756 
ems_allele:
CycE2
CycE3
CycEAR95
P_element_allele:
CycE01672
CycE05206 sequenced
CycE05277
CycE05278
CycE10427
CycE25-14
CycEk00807
CycEk02602 sequenced
CycEk05007 sequenced
CycEk09109
misc_allele:
CycE4
CycE50-2
TE_insert_allele:
CycE5 (Tp(1;2)TE35D)
aberration_associated_allele:
CycE1 (T(2;3)G16)
phenotypic_class: vital; hypomorphic alleles female sterile.
SM_notes: Translation for type 2 from alignment of GenBank X75027 on
DS09217(1-284)
and DS07108, type 1 from GenBank X75026 on DS07108.
===========================================================================
\+symbol:  BG:DS09217 .1
\+formal_name:  BG:DS09217 .1
genefinder: 36
genscan: 60
product:
match_to: (TR Q23597 e-6 W)
EST: HL02152.5'; GH01660.5'
P1: DS09217
direction: -
SM_notes: Translation from full-length GH01660. Evidence for alternative
splicing
since second exon of HL02152.5' extends further 3' than that of GH01660.
===========================================================================
\+symbol: l(2)35Df
\+formal_name:  BG:DS09217 .2
name: lethal (2) 35Df
UID: FBgn0001986
references:
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)TE35D-1 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)b88c75 (FBrf0092813)
ems_allele:
l(2)35Df1
l(2)35Df2
l(2)35Df3
l(2)35Df4
l(2)35DfHL58
P_element_allele:
l(2)35Dfk14423 sequenced k14422 cluster
genefinder: 161 (2 spans)
genscan: 404
product: MTR4 ATP-dependent RNA helicase
match_to: SP P42285 0 H
match_to: GB D29641 0 H (KIAA0052)
match_to: SP Q15477 e-141 H
match_to: SP P47047 e-264 Y
match_to: GB Z49325 e-262 Y
match_to: SP Q23223 e-243 W
match_to: TR G2944423 e-133 M
match_to: TR O04538 e-40 A
EST: LD10786.5'; LD10786.3'; GM09051.5'; LD02559.5'; LD05183.5';
LD12317.5'; LD12395.5'; LD20038.5'; LD27110.5'; LD28043.5'
P1: DS09217
direction: +
phenotypic_class: vital; escapers HL58 female sterile, small bristles.
SM_notes: Translation from full-length LD10786 and LD27110.5', because
something
fishy with LD10786 (has intron where other cDNAs from ESTs don't).
P is inserted at 6949 of DS09217. The cDNA for  BG:DS09217 .1 is GH01660,
and the full-length sequence is from 5693 to 4243 of DS09217 (reverse strand).
The cDNA for  BG:DS09217 .2 is LD10786, and its full length sequence is from
6962 to 10532 (forward strand). However, the EST LD02559 extends even further
5', and starts at 6936.
===========================================================================
symbol: l(2)35Di
name: lethal (2) 35Di
UID: FBgn0001989
references:
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)TE35D-1 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)b88c75 (FBrf0092813)
ems_allele:
l(2)35DiRAR8
phenotypic_notes: escapers with held out wings.
phenotypic_class: vital.
===========================================================================
\+symbol: Gli
\+formal_name:  BG:DS09217 .3
name: Gliotactin
synonym: l(2)35Dg
UID: FBgn0001987
references:
FBrf0081345 == Auld et al., 1995, Cell 81(5): 757--767
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)TE35D-1 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)b88c75 (FBrf0092813)
product: gliotactin
product: serine esterase \like
genefinder: 100
genscan: 216 (7 spans)
match_to: TR Q62888 e-53 O (rat)
match_to: GB U22952 e-46 O (rat)
match_to: TR Q20826 e-47 W
match_to: SP P22303 e-43 H
match_to: SP P21836 e-43 M
match_to: LD07724.5' e-8; LD02542.5' e-6; LD30351.5' e-5
EST:
P1: DS09217
direction: -
motifs: Transmembrane domain protein.
 cDNA_sequence:L39083 ; g899062
 pr_sequence_TREMBL:Q24350 
 pr_sequence_PIR:A56920 
ems_allele:
Gli1
Gli2
Gli3
Gli4
GliRAR77
P_element_allele:
GliAE2 sequenced Auld
GliJ29 sequenced Auld
GlirL82 sequenced Auld
k09033 sequenced
EP(2)2322 sequenced
EP(2)2416 sequenced
EP(2)2306 sequenced
EP(2)2463 sequenced
EP(2)2615 sequenced
P_element_derivative_allele:
GliAE2Δ45
GliAE2Δ4a
GliAE2Δ4b
GliAE2Δ6a
GliJ29Δ7b
phenotypic_class: vital.
JR_notes: k09033 viable and fertile.
SM_notes: Translation from alignment of GenBank L39083. Gli from 17386-10808.
EP2322, EP2416 at 17422, EP2306, EP2463, & EP2615 at 17429, l(2)k09033 at
17487.
===========================================================================
\+symbol:  BG:DS09217 .4
\+formal_name:  BG:DS09217 .4
genefinder: 64
genscan: 105
product:
match_to: SP P46554 e-52 W
match_to: GB AA461616 e-26 H (Hum EST)
match_to: TR G3258571 e-16 A
match_to: YPD 927710 e-8 Y
match_to: GB AA118474 e-17 M (Mus EST)
EST: LD08227.3'; LD08227.5'
P1: DS09217
direction: +
JR_notes: could be 35Di, 35De or 35Dh (see next record).
SM_notes: Translation from full-length LD08227.
===========================================================================
\+symbol: l(2)35Ea
\+formal_name:  BG:DS09217 .5
name: lethal (2) 35Ea
UID: FBgn0001990
references:
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)TE35BC-34
(FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)n78l3 (FBrf0051973)
genefinder: 67
genscan: 137
product: Zinc finger protein
match_to: TR D1024956 e-27 H
match_to: TR Q62516 e-24 M
match_to: TR Q22874 e-12 W
match_to: TR O02265 e-12 W
match_to: SP P47043 e-8 Y
EST: LD02957.3'; LD02957.5'; LD22579.5'; LD22579.3'
P1: DS09217
direction: -
P_element: PZ05271 sequenced Gates
ems_allele:
l(2)35EaRAR14
misc_allele:
l(2)35EaAM11
phenotypic_class: vital.
SM_notes: Translation from full-length LD02957.
Julie Gates in Thummel's lab sequenced l(2)05271 by plasmid
rescue, first bp of 275bp fragment (insertion site) maps to 22957
(276=22638), 281bp upstream from start of LD02957 (22676-21313) and 5bp
downstream from the start of LD22579.5' (22962-22362).
JR_notes: 05271 viable and fertile over deletions of 34-36, including 35D,
so P not associated with lethality in strain.
All but one of the excisions and male recombinants are viable over r10;
exception male recombinant is l(2)35Ea.
Some excisions over progenitor crippled legs and disrupted wings, therefore
DS09217.5 =l(2)35Ea and PZ05271 has a weak crippled leg and reduced wing
phenotype when heterozygous with a deletion.
===========================================================================
\+symbol:  BG:DS09217 .6
\+formal_name:  BG:DS09217 .6
genefinder: 97
genscan: 262
product: Ku ATP-dep. DNA helicase II, 86kD subunit
match_to: SP P27641 e-20 M
match_to: SP P13010 e-15 H
EST:
P1: DS09217
direction: -
SM_notes: Translation from Genefinder. Kerrie reports hits from LD
A8-F8(6) library.
JR_notes: could be 35Di, 35De or 35Dh (see previous record).
==========================================================================
symbol: l(2)35De
name: lethal (2) 35De
UID: FBgn0001985
references:
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)TE35D-1 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)TE35BC-34 (FBrf0051973)
aberration_associated_allele:
l(2)35De1 (In(2L)NS)
phenotypic_class: vital.
status: uncertain.
===========================================================================
symbol: l(2)35Dh
name: lethal (2) 35Dh
UID: FBgn0001988
references:
cytology: 35D7--35D7
cytology_data: Left limit from non-inclusion within Df(2L)TE35BC-34
(FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)n78l3 (FBrf0051973)
ems_allele:
l(2)35DhAS64
phenotypic_class: vital.
===========================================================================
\+symbol:  BG:DS02252 .3
\+formal_name:  BG:DS02252 .3
genefinder:
genscan: 376
product: ypt6 suppressor
match_to: YPD 577221 e-7 Y
EST:
P1: DS02252
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR product from GH(1)
library.
==========================================================================
\+symbol:  BG:DS02252 .4
\+formal_name:  BG:DS02252 .4
genefinder:
genscan: 71
product:
match_to: SP P12036 e-8 H
EST:
P1: DS02252
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR product from GH(1)
library.
==========================================================================
\+symbol:  BG:DS02252 .1
\+formal_name:  BG:DS02252 .1
genefinder: 48
genscan: 129
product:
match_to:
EST:
P1: DS02252
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR product from GH(2)
and LP(3) libraries.
==========================================================================
\+symbol:  BG:DS02252 .2
\+formal_name:  BG:DS02252 .2
genefinder: 40(DS02252)/61(DS00365)
genscan: 86(DS02252)/189(DS00365)
product: tektin A1
match_to: GB M97188 e-9(DS02252)/e-50(DS00365) O (sea urchin)
match_to: TR Q26623 e-8(DS02252)/e-37(DS00365) O (sea urchin)
match_to: TR G3005677 e-31(DS00365) H
match_to: GB AA108986 e-8(DS02252)/e-18(DS00365) M (Mus EST)
match_to: TR Q21641 e-14(DS00365) W
EST:
P1: DS02252, DS00365
direction: +
SM_notes: Translation from Genscan on DS00365. Kerrie reports PCR products
from GH(3) and LP(2) libraries.
==========================================================================
\+symbol:  BG:DS00365 .1
\+formal_name:  BG:DS00365 .1
genefinder: (14)
genscan: 96
product: aminopeptidase N
match_to: SP P15684 e-52 O (rat)
match_to: SP P15144 e-48 H
match_to: SP P97449 e-43 M
match_to: TR Q21673 e-34 W
match_to: SP P32454 e-31 Y
EST:
P1: DS00365
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR product from GH(3)
and LP(2) libraries.
==========================================================================
\+symbol:  BG:DS00365 .2
\+formal_name:  BG:DS00365 .2
genefinder: 38
genscan: 253
product: alpha-macroglobulin
match_to: TR E1247576 e-107 W
match_to: TR E1247575 e-107 W
match_to: TR Q60486 e-80 O (guinea pig)
match_to: SP P20742 e-76 H
match_to: GB X54380 e-75 H
match_to: SP Q61838 e-66 M
match_to: HL07316.5' e-23; HL04948.5' e-21
EST:
P1: DS00365
direction: -
M
SM_notes: Translation from Genscan. Kerrie reports PCR product from LP(4)
library.
==========================================================================
\+symbol:  BG:DS00365 .3
\+formal_name:  BG:DS00365 .3
genefinder: 51
genscan: 170
product: carboxypeptidase
match_to: TR E1247396 e-52 W
match_to: SP P42660 e-37 O (mosquito)
match_to: GB L46594 e-32 O (mosquito)
match_to: GB AA117009 e-26 M (Mus EST)
match_to: GB AA118637 e-26 M (Mus EST)
match_to: TR O04084 e-17 A
match_to: SP P32826 e-26 A
match_to: SP P38109 e-19 Y
match_to: SP P09620 e-15 Y
match_to: SP P10619 e-13 H
match_to: TR E1296581 e-13 H
EST:
P1: DS00365
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR product from GH(2)
and LP(2) libraries.
==========================================================================
\+symbol: beat-B
\+formal_name:  BG:DS00365 .4
name: beaten path-B
UID:
references:
Teg Pipes <teg@XXXX> to JR 29 May 1997
genefinder:
genscan: 127(DS00365)/(30)(DS07486)
match_to: TR Q94534 e-41 D(DS00365)
EST:
P1: DS00365, DS07486
direction: -
SM_notes: Translation from alignment of cDNA sequence from T. Pipes on DS00365
(3';1148-2590) and DS07486 (5';17-1147).
===========================================================================
\+symbol:  BG:DS07486 .3
\+formal_name:  BG:DS07486 .3
genefinder:
genscan: 300
product: serine protease
match_to: TR P91817 e-31 O (horseshoe crab)
match_to: GB D87214 e-29 O (horseshoe crab)
match_to: SP P26262 e-22 M
match_to: SP P40313 e-20 H
match_to: TR Q17800 e-14 W
EST: LP01559.5'
P1: DS07486
direction: +
Nested_in: beat-B
SM_notes: Translation from full-length LP01559.
==========================================================================
\+symbol:  BG:DS07486 .4
\+formal_name:  BG:DS07486 .4
genefinder:
genscan: 70
product:
match_to:
EST:
P1: DS07486
direction: +
Nested_in: beat-B
SM_notes: Translation from Genscan. Kerrie reports PCR products from GH(3)
and LP(3) libraries.
==========================================================================
\+symbol:  BG:DS07486 .5
\+formal_name:  BG:DS07486 .5
genefinder:
genscan: 63
product:
match_to:
EST:
P1: DS07486
direction: +
Nested_in: beat-B
SM_notes: Translation from edited Genscan (took out 2 exons--low
probabilities). Kerrie reports PCR products from GH(3) and LP(3) libraries.
===========================================================================
\+symbol:  BG:DS07486 .2
\+formal_name:  BG:DS07486 .2
genefinder: 24
genscan: 54
product: outer arm dynein light chain 2
match_to: TR D1025094 e-34 O (sea urchin)
match_to: GB AA923426 e-12 H (Hum EST)
match_to: YPD 486343 e-8 Y
EST:
P1: DS07486
direction: +
SM_notes: Translation from Genscan.
===========================================================================
symbol: fs(2)35Ec
phenotypic_class: female_sterile
JR_notes: No alleles; overlapping deletion phenotype.
===========================================================================
symbol: ms(2)35Eb
name: male sterile (2) 35Eb
UID: FBgn0004075
references:
FBrf0082309 == Mahone et al., 1995, EMBO J. 14(9): 2043--2055
cytology: 35E1--35E1
cytology_data: Left limit from inclusion within Df(2L)RA5 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)Sco7 (FBrf0051973)
phenotypic_class: male_sterile.
JR_notes: No alleles; overlapping deletion phenotype.
===========================================================================
symbol: fs(2)35Ed
phenotypic_class: female_sterile
JR_notes: No alleles; overlapping deletion phenotype.
===========================================================================
\+symbol: beat-C
\+formal_name:  BG:DS00913 .1
name: beaten path-C
UID:
references:
Teg Pipes <teg@XXXX> to JR 29 May 1997
genefinder: 26(DS00913)
genscan: 157(DS00913)
product:
match_to: TR Q94534 e-169 D
EST:
P1: DS08681, DS00913
direction: +
MA_notes: TE35D-GW19/RM5 is viable; hence beat-C is not lethal; = fs(2)35Ed ?.
SM_notes: Translation from alignment of cDNA sequence from T. Pipes on
DS08681 (5';10-791) and on DS00913 (3';718-4031).
===========================================================================
\+symbol: BicC
\+formal_name:  BG:DS00913 .2
name: Bicaudal C
UID: FBgn0000182
references:
FBrf0082309 == Mahone et al., 1995, EMBO J. 14(9): 2043--2055
FBrf0079309 == Saffman et al., 1995, A. Conf. Dros. Res. 36: 128B
FBrf0087607 == Micklem, 1995, Dev. Biol. 172(2): 377--395
cytology: 35E1--35E1
cytology_data: Left limit from non-inclusion within Df(2L)Sco7 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)fn26 (FBrf0051973)
genefinder: 130
genscan: 270(10 spans)
product: RNA-binding-protein
match_to: TR Q21593 e-12 W
EST: LD07303.5'; LD20765.5'; LD08973.5'; CK01824.3'; LD17549.5';
LD22511.5'; LD22888.5'
P1: DS00913
direction: +
motifs: KH domain protein.
homology: species == Homo sapiens; gene == IMAGE: 25351; EMBL: R12003; DRES: 46
 genomic_sequence:U15928 ; g1932822
 pr_sequence_TREMBL:Q24009 
 pr_sequence_PIR:S55051 
ems_allele:
BicC1
BicC2
BicC3
BicC4
BicC5
BicCAA29
BicCAA4
BicCAB74
BicCAB79
BicCAR108
BicCAR72
BicCAR96
BicCPE37
BicCPX1
BicCQL53
aberration_associated_allele:
BicCSco-rv18 (Df(2L)Scorv18)
BicCTE35D-19 (Df(2L)TE35D-19)
phenotypic_class: female_sterile.
SM_notes: Translation from alignment of EMBL U15928 (curated by MA).
JR_notes: Sco-rv18 is beat- according to Fambrough, therefore not BicC
allele.
===========================================================================
\+symbol: beat
\+formal_name:  BG:DS00913 .3
name: beaten path
synonym: tric
UID: FBgn0013433
references:
FBrf0057894 == van Vactor et al., 1993, Cell 73(6): 1137--1153
FBrf0091058 == Fambrough and Goodman, 1996, Cell 87(6): 1049--1058
FBrf0074804 == Wilson, 1993, Curr. Biol. 3: 536--539
FBrf0092815 == Tessier-Lavigne and Goodman, 1996, Science 274(5290):
1123--1133
FBrf0101922 == Holmes et al., 1998, Genetics 148: 1189--1201
cytology: 35E1--35E1
cytology_data: Left limit from inclusion within Df(2L)RM5 (FBrf0091058)
cytology_data: Right limit from molecular mapping relative to BicC
(FBrf0091058)
genefinder: (16)
genscan: 106
product:
match_to:
EST:
P1: DS00913
direction: +
 cDNA_sequence:U67057 ; g1519540
 pr_sequence_TREMBL:Q94534 
ems_allele:
beat1
beat2
beat3
beattric
aberration_associated_allele:
In(2L)C163.41
In(2L)dppd36
phenotypic_class: vital.
MA_notes: email from Heilig says that tric=beat (see email: From
heilig@XXXX Wed Apr 29  18:57:23  1998)
SM_notes: Translation from alignment of GenBank U67057.
===========================================================================
\+symbol:  BG:DS04095 .1
\+formal_name:  BG:DS04095 .1
genefinder: (10)
genscan: 64
product:
match_to:
EST: GH09478.5'
P1: DS04095
direction: +
SM_notes: Translation from full-length GH09478 (different from Genscan at 3').
===========================================================================
\+symbol:  BG:DS04095 .2
\+formal_name:  BG:DS04095 .2
genefinder: (15)
genscan: 53
product:
match_to: TR O16053 e-7 D (D.yakuba)
EST:
P1: DS04095
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol:  BG:DS04095 .3
\+formal_name:  BG:DS04095 .3
genefinder:
genscan:
product:
match_to:
EST: GH12941.3'
P1: DS04095
direction: +
SM_notes: Translation from Genscan.
===========================================================================
\+symbol: Ca-α1D
\+formal_name:  BG:DS02795 .1
name: Ca2+-channel protein α1 subunit D
synonym: l(2)35Fa
UID: FBgn0001991
references:
FBrf0080516 == Zheng et al., 1995, J. Neurosci. 15(2): 1132--1143
FBrf0082309 == Mahone et al., 1995, EMBO J. 14(9): 2043--2055
cytology: 35F1--35F1
cytology_data: Left limit from sequence databank entry U00690
cytology_data: Right limit from inclusion within Tp(2;2)A446 (citation
unavailable)
genefinder: 74/37/56/(18)
genscan: 626/(38)
product: Ca2+-channel-protein-α1-subunit
match_to: TR Q18698 0 W
match_to: SP P24827 e-7 B
match_to: TR Q13931 0 H
match_to: TR Q01815 0 M
match_to: SP P50077 e-12 Y
EST: GH02029.5'; GH02129.5'; HL01607.5'
P1: DS02795
direction: +
 cDNA_sequence:U00690 ; g457927
 pr_sequence_TREMBL:Q24270 
ems_allele:
Ca-α1DAR66
Ca-α1DX10
Ca-α1DX7
misc_allele:
Ca-α1DIK2
phenotypic_class: vital.
SM_notes: Translation from alignment of EMBL U00690 (curated). Many other
Ca channels from other species showed high homology,
but these are just a random selection.
===========================================================================
\+symbol:  BG:DS02795 .3
\+formal_name:  BG:DS02795 .3
genefinder:
genscan: 108(DS02795)/63(DS07473)
product:
match_to:
EST:
P1: DS02795, DS07473
direction: +
SM_notes: Translation from 3' edited Genscan on DS02795. Kerrie reports
PCR products from GH(1) and LP(2) libraries.
===========================================================================
\+symbol:  BG:DS07473 .1
\+formal_name:  BG:DS07473 .1
genefinder: 104
genscan: 506
product: calcium channel
match_to: TR O08536 e-62 M
match_to: TR O08533 e-62 M
match_to: TR O08535 e-62 M
match_to: TR O08534 e-62 M
match_to: TR O08532 e-62 M
match_to: SP P54289 e-62 H
match_to: SP P34374 e-48 W
match_to: YPD 1015903 e-22 Y
EST:
P1: DS07473
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR products from LD
A8-F8(3) library.
==========================================================================
\+symbol: PRL-1
\+formal_name:  BG:DS07473 .3
name: putative prenylated protein tyrosine phosphatase
UID: FBgn0024734
genefinder: (14)
genscan: (39)
product: protein tyrosine phosphatase (prenylated)
match_to: TR Q15259 e-23 H
match_to: TR Q12974 e-23 H
match_to: TR G2992630 e-23 M
match_to: TR G3152650 e-31 W
match_to: TR Q22582 e-31 W
match_to: GB U42846 e-11 W
EST: LD12894.3'; LD12894.5'; CK00486.5'; GM07690.5'; GM14563.5';
GM14708.5'; GM14720.5'; LD18273.5'; LD20164.5'; GH03107.5'; LD33945.5';
LD33967.5'; LD33906.5'; LD34413.5'
P1: DS07473
direction: -
 cDNA_sequence:AF063902 ; g3135664
enzyme: protein-tyrosine-phosphatase (prenylated) == EC 3.1.3.48
P_element_allele:
l(2)PZ03264 sequenced
k09834 sequenced
EP(2)0311 sequenced
EP(2)2048 sequenced
phenotypic_class: not vital
phenotypic_notes: wing phenotype over deletions (Df(2L)el18, Df(2L)RN2).
MA_notes: l(2)03264 has two inserts; that associated with this gene in
FlyBase (FBgn0010534) is the 27F insertion.
JR_notes: all excisions of 03264 are viable. EP(2)0311 is female
semi-sterile o
ver certain deletions in the 35F vicinity.
SM_notes: Translation from full-length LD12894.
LD12894 is significantly longer at the 5' end (a little longer at 3' end too)
than AF063902 in GenBank. PZ03264 maps at 3235, EP(2)0311 maps at 8524,
EP(2)2048 at 8597, k09834 at 8497. PRL-1 exon 1 is 2857 to 3346, exon 2
is 10
264 to 10341.
==========================================================================
\+symbol:  BG:DS07473 .2
\+formal_name:  BG:DS07473 .2
genefinder: 48
genscan: 146
product:
match_to:
EST: LD25338.5'; LD29644.5'
P1: DS07473, (DS02740)
direction: +
SM_notes: Translation from full-length LD25338. LD25338 full length sequence
only 1-1323 of 3159 bp aligns to DS07473, and the 3' end is not on any
other P1
(DS02740, DS09218, or DS02780). Could be a very, very long intron or
chimeric clone.
===========================================================================
\+symbol: twe
\+formal_name:  BG:DS02740 .1
name: twine
 synonym:l (2)35Fh
UID: FBgn0002673
UID: FBgn0016862
references:
FBrf0055587 == Alphey et al., 1992, Cell 69: 977--988
FBrf0074608 == Thomas et al., 1994, Cell 77(7): 1003--1014
FBrf0073190 == Gonczy et al., 1994, Cell 77(7): 1015--1025
FBrf0055870 == Courtot et al., 1992, Development 116(2): 405--416
cytology: 35F1--35F7
cytology_data: Left limit from inclusion within Df(2L)RN2 (FBrf0055870)
cytology_data: Right limit from non-inclusion within Df(2L)II30 (citation
unavailable)
enzyme: protein-tyrosine-phosphatase == EC 3.1.3.48
genefinder: 45
genscan: 123
product: protein-tyrosine-phosphatase
match_to: SP Q29029 e-40 O (pig)
match_to: SP P30307 e-39 H
match_to: SP P48967 e-37 M
match_to: SP P30606 e-33 M
match_to: SP P30634 e-21 W
match_to: SP P23748 e-18 Y
EST: LD04211.5'; LD02913.5'; LD10764.5'; LD16907.5; LD19349.5'; LD19391.5';
LD20092.5'; LD23305.5'
P1: DS07473, DS02740
direction: -
homology: species == Schizosaccharomyces pombe; gene == cdc25
 cDNA_sequence:M94158 ; g157056
 cDNA_sequence:X69018 ; g8756
 pr_sequence_SwissProt:Q03019 
 pr_sequence_PIR:A41910 
 pr_sequence_PIR:S26692 
misc_allele:
twe1
P_element_allele:
k08310
EP(2)0613 sequenced
aberration_associated_allele:
tweDTD22 (T(2;4)DTD22)
Df(2L)RN2 broken within twe
phenotypic_class: maternal_effect_lethal; male_sterile.
SM_notes: Translation from alignment of GenBank M94158.
JR_notes: k08310 is female fertile. Synthetic deletion T(2;4)GV101 DTD22
is lethal with RN2.
Both RN2 and DTD22 break in twe (RN2 has been molecularly mapped, DTD22 is
mutant for twe), so the new synthetic and RN2 should only overlap for
twe, therefore twe = 35Fh.
===========================================================================
\+symbol:  BG:DS02740 .2
\+formal_name:  BG:DS02740 .2
synonym: MET30
genefinder: 20
genscan: 60
product:
match_to: TR Q19986 e-43 W
match_to: GB AA008890 e-15 M (Mus EST)
match_to: GB AI147754 e-15 H (Hum EST)
EST:
P1: DS02740
direction: +
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
===========================================================================
\+symbol: crp
\+formal_name:  BG:DS02740 .3
name: cropped
synonym: lethal (2) 35Fd
UID: FBgn0001994
references:
FBrf0092259 == Chiu and Krasnow, 1997, A. Conf. Dros. Res. 38: 229A
cytology: 35F1--35F2
cytology_data: Left limit from inclusion within Df(2L)RN2 (FBrf0051973)
cytology_data: Right limit from inclusion within Df(2L)TE35D-13 (FBrf0092813)
genefinder: (11)/94
genscan: 223
product: AP-4
match_to: SP Q01664 e-16 H
match_to: SP P34474 e-11 W
match_to: SP P26687 e-11 M
EST: LD12417.3'; LD12417.5'; LD02349.5'; LD02353.5'; GM01378.5';
GM03832.5'; GM08317.5'; GM08864.5'; LD04473.5'; LD05189.5'; LD07249.5';
LD11116.5'; LD18457.5'; LD21475.5'; LD26263.5'; LD28118.5'; LD34528.5';
LD27601.5'
P1: DS02740
direction: -
ems_allele:
l(2)35FdRAR46
P_element_allele:
l(2)35Fd00232 sequenced
l(2)35Fd03101
l(2)35Fd06872
l(2)35Fdk00809
k05211
l(2)35Fdk05519 cluster: k05527
l(2)35Fdk05601 cluster:
k05635;k05648;k05608;k05616;k05625;k05640;k05642;k05649
l(2)35Fdk05814
l(2)35Fdk06207
l(2)35Fdk07829 sequenced
l(2)35Fdk08007
l(2)35Fdk08806
l(2)35Fdk09214 cluster: k09225;k09232
l(2)35Fdk09704
l(2)35Fdk10415
l(2)35Fdk11024
l(2)35Fdk13611
l(2)35Fdk16129
l(2)35Fdk21602
EP(2)0721 sequenced
EP(2)0814 sequenced in Su(Ste) sequence
k03505
misc_allele:
l(2)35Fd2
phenotypic_class: vital.
phenotypic_notes: Required for tracheal branching (FBrf0092259); pupal
lethal (k11024, BDGP); early-larval lethal (k09232, k05519, BDGP).
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
===========================================================================
\+symbol:  BG:DS02740 .4
\+formal_name:  BG:DS02740 .4
genefinder: 70
genscan: 236
product: un-1 (protein kinase A anchoring protein)
match_to: TR G2707344 e-35 H
match_to: TR Q10955 e-11 W
EST: HL02329.5'
P1: DS02740
direction: +
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
==========================================================================
\+symbol:  BG:DS02740 .5
\+formal_name:  BG:DS02740 .5
genefinder: 23
genscan: (33)
product:
match_to:
EST:
P1: DS02740
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR products from
GM(1), GH(1), and LP(2) libraries.
==========================================================================
\+symbol: l(2)35Fb
\+formal_name:  BG:DS02740 .6
name: lethal (2) 35Fb
UID: FBgn0001992
references:
genefinder: 53
genscan: 142
product: cytochrome P450
match_to: GB U44753 e-41 D (Cyp18)
match_to: SP Q95078 e-40 D (Cyp18)
match_to: SP P00178 e-56 O (rabbit)
match_to: SP P20813 e-51 H
match_to: TR G2920650 e-51 M
match_to: TR G2736526 e-42 W
match_to: TR D1029479 e-25 A
EST:
P1: DS02740
direction: +
cytology: 35F1--35F12
cytology_data: Left limit from inclusion within Df(2L)II30 (FBrf0092813)
cytology_data: Right limit from inclusion within Df(2L)II30 (FBrf0092813)
spontaneous_allele
l(2)35Fbck
ems_allele:
l(2)35FbAS96
phenotypic_class: vital; escapers disorientated (Willingham).
SM_notes: Translation from Genscan. Cyp2b homolog; no longer have any cDNA
sequence (Ling & Damon couldn't find).
===========================================================================
\+symbol: heix
\+formal_name:  BG:DS02740 .7
name: heixuedian
synonym: lethal (2) 35Fc
synonym: l(2)35Fc
synonym: ipa-6d
UID: FBgn0001993
references:
cytology: 35F6--35F7
cytology_data: Left limit from in situ hybridisation (FBrf0067338)
cytology_data: Right limit from in situ hybridisation (FBrf0067338)
genefinder: 43
genscan: 103
product: ipa-6d
match_to: GB AA087043 e-41 M (Mus EST)
match_to: GB W58989 e-15 M (Mus EST)
match_to: GB AA306118 e-27 H (Hum EST)
match_to: GB R52058 e-13 H (Hum EST)
EST: LD08373.5'; CK02500.5'; LD06174.5'; LD08295.5'; LD09003.5';
LD10383.5'; LD13786.5'; LD14441.5'; LD14872.5'; LD15648.5'; LD16196.5';
LD18123.5'; LD18475.5';
P1: DS02740
direction: -
ems_allele:
l(2)35Fc1
P_element_allele:
l(2)35Fck11403 sequenced
l(2)35Fck12401 sequenced
l(2)k07114
misc_allele:
l(2)35Fc91k
phenotypic_class: vital.
phenotypic_notes: pupal lethal (k07114, BDGP).
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
===========================================================================
\+symbol:  BG:DS02740 .8
\+formal_name:  BG:DS02740 .8
genefinder: (11)
genscan: 70
product: mkr2 (zinc finger)
match_to: TR E1308763 e-26 D (Kr-H)
match_to: TR E1308765 e-26 D (Kr-H)
match_to: SP P51523 e-31 H
match_to: TR Q92951 e-32 H
match_to: SP Q13360 e-32 H
match_to: TR Q62512 e-32 M
match_to: SP P15620 e-29 M
match_to: TR Q22874 e-23 W
match_to: TR O02265 e-23 W
match_to: SP P47043 e-18 Y
EST:
P1: DS02740
direction: +
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey (5' and 3' ends) and Genscan in middle.
==========================================================================
\+symbol:  BG:DS02740 .9
\+formal_name:  BG:DS02740 .9
genefinder: (15)
genscan:
product: glial maturation factor
match_to: TR D1019982 e-22 H
match_to: SP P17774 e-23 H
match_to: SP Q63228 e-28 O (rat)
match_to: GB W50254 e-20 M (Mus EST)
EST:
P1: DS02740
direction: -
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
==========================================================================
\+symbol:  BG:DS02740 .10
\+formal_name:  BG:DS02740 .10
genefinder:
genscan: 54
product: un-4
match_to:
EST: GM03132.5'; GM03132.3'; CK01361.c
P1: DS02740
direction: +
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey and GM03125.5and3 at 5' and 3' ends (extend longer).
==========================================================================
\+symbol: anon-35Fa
\+formal_name:  BG:DS02740 .11
synonym: ZK4118
UID: FBgn0015338
references:
FBrf0082538 == Roth et al., 1995, Cell 81(6): 967--978
cytology: 35F6--35F12
cytology_data: Left limit from molecular mapping relative to cni (FBrf0082538)
cytology_data: Right limit from inclusion within Df(2L)III18 (FBrf0082538)
genefinder: 26
genscan: (36)
product: ZK4118
match_to: TR E1318685 e-31 H
match_to: GB AA139591 e-28 M (Mus EST)
match_to: GB AA485358 e-14 H (Hum EST)
match_to: TR Q23483 e-12 W
EST: GM07085.5'; GM13502.5'; LD33770.5'
P1: DS02740
direction: -
FB_internal_note: Encodes 1kb transcript III in Fig 6A pg 973.
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
===========================================================================
\+symbol: Sed5
\+formal_name:  BG:DS02740 .12
synonym: lethal (2) 35Ff
synonym: = anon-35Fb
UID: FBgn0001996
UID: FBgn0015339
UID: FBgn0011708
references:
FBrf0081366 == Banfield et al., 1994, J. Cell Biol. 127(2): 357--371
FBrf0082538 == Roth et al., 1995, Cell 81(6): 967--978
cytology: 35F1--35F12
cytology_data: Left limit from inclusion within Df(2L)RN2 (FBrf0051973)
cytology_data: Right limit from non-inclusion within Df(2L)III18 (citation
unavailable)
genefinder: 53
genscan: 117
product: vesicle-targeting-protein
match_to: SP Q13190 e-71 H
match_to: SP Q20797 e-46 W
match_to: GB AA072141 e-31 M (Mus EST)
match_to: SP Q01590 e-22 Y
match_to: TR G2981439 e-19 A
EST: LD02623.3'; LD02623.5'; GM06766.5'; LD28045.5'; LD29042.5'
P1: DS02740
direction: +
homology: species == Saccharomyces cerevisiae; gene == SED5; SGDID: L0001861
 cDNA_sequence:X78219 ; g467559
 pr_sequence_TREMBL:Q24509 
 pr_sequence_PIR:S43101 
ems_allele:
l(2)35FfAR113
phenotypic_class: vital.
FB_internal_note: Encodes 1.7kb transcript II in Fig 6A pg 973.
SM_notes: Translation from alignment of GenBank X78219.
===========================================================================
\+symbol: cni
\+formal_name:  BG:DS02740 .13
name: cornichon
UID: FBgn0000339
references:
FBrf0082538 == Roth et al., 1995, Cell 81(6): 967--978
cytology: 35F6--35F12
cytology_data: Left limit from inclusion within Df(2L)III18 (FBrf0082538)
cytology_data: Right limit from inclusion within Df(2L)II30 (FBrf0092813)
homology: species == Homo sapiens; gene == IMAGE: 51056; EMBL: H18748; DRES: 82
genefinder: (11)
genscan:
product:
match_to: TR Q22361 e-21 W
match_to: GB Z78065 e-10 W
match_to: TR O35372 e-29 M
match_to: GB AA049525 e-28 M (Mus EST)
match_to: GB AA309041 e-20 H (Hum EST)
match_to: GB H18748 e-17 H (Hum EST)
EST:
P1: DS02740
direction: -
 cDNA_sequence:U28069 ; g886769
 pr_sequence_PIR:A56724 
 pr_sequence_SwissProt:P49858 
ems_allele:
cni1
cniAA12 aka AA112 ?
cniCF5
phenotypic_class: maternal_effect_lethal.
SM_notes: Translation from alignment of GenBank U28069.
===========================================================================
\+symbol: fzy
\+formal_name:  BG:DS02740 .14
name: fizzy
UID: FBgn0001086
references:
FBrf0081900 == Dawson et al., 1995, J. Cell Biol. 129(3): 725--737
FBrf0058082 == Dawson et al., 1993, Development 117(1): 359--376
FBrf0084373 == Sigrist et al., 1995, EMBO J. 14(19): 4827--4838
FBrf0085992 == Stratmann and Lehner, 1996, Cell 84(1): 25--35
cytology: 35F6--35F12
cytology_data: Left limit from inclusion within Df(2L)III18 (FBrf0082538)
cytology_data: Right limit from inclusion within Df(2L)II30 (FBrf0092813)
homology: species == Saccharomyces cerevisiae; gene == cdc20; SGDID: L0000259
genefinder: 65
genscan: 114
product:
match_to: TR Q12834 e-120 H
match_to: TR G3088632 e-119 O (rat)
match_to: GB AA008043 e-34 M (Mus EST)
match_to: TR E1310059 e-83 A
match_to: TR Q09649 e-71 W
match_to: SP P53197 e-65 Y
match_to: SP P26309 e-55 Y
EST: LD08545.5'; CK02051.3'; GM02166.5'; GM10572.5'; LD08754.5';
LD11224.5'; LD12520.5'; LD13309.5'; LD14034.5'; LD18042.5'; LD18190.5';
LD22440.5'; LD22633.5'; LD22763.5'; LD23923.5'; LD24209.5'; LD24520.5';
LD24735.5'; LD33694.5'; LD26949.5'; LD30572.5'; LD31127.5'; GH02903.5';
LD32995.5'; LD34516.5'
P1: DS02740
direction: +
 cDNA_sequence:U22419 ; g1109772
 pr_sequence_TREMBL:Q24044 
ems_allele:
fzy1
fzy2
fzy3
X_ray_allele:
fzyID
misc_allele:
fzy4
fzy5
fzy6
fzy7
fzy8
P_element_allele:
EP(2)1028 sequenced
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank U22419.
===========================================================================
\+symbol: cact
\+formal_name:  BG:DS02740 .15
name: cactus
UID: FBgn0000250
references:
FBrf0053786 == Roth et al., 1991, Development 112: 371--388
FBrf0055573 == Geisler et al., 1992, Cell 71: 613--621
FBrf0055575 == Kidd, 1992, Cell 71: 623--635
cytology: 35F6--35F12
cytology_data: Left limit from inclusion within Df(2L)III18 (FBrf0082538)
cytology_data: Right limit from inclusion within Df(2L)II30 (FBrf0092813)
motifs: Ankyrin-repeat protein.
genefinder: 51/(20)
genscan: 143/(33)
product:
match_to: TR Q08353 e-11 O (pig)
EST: LD10835.5'; CK01266.5'; CK01266.5'; HL04371.5'; HL04374.3';
LD03018.5'; LD03773.5'; LD05260.5'; LD08581.5'; LD10168.5';
LD10910.5'; LD13068.5'; LD14407.5'; LD14691.5'; LD15008.5';
LD16234.5'; LD17086.5'; LD19013.5'; LD19965.5'; LD21118.5';
LD23729.5'; LD24255.5'; LD26362.5'; LD30959.5'; LD30371.5'; LD33294.5';
LD33754.5'; LD33069.5'; LD31391.5'; LD34227.5'; LD28651.5'; LD29203.5'
P1: DS02740
direction: -
homology: species == Saccharomyces cerevisiae; gene == SWI6; SGDID: L0002254
homology: species == Homo sapiens; gene == NFKBI; GDB: 131399; OMIM: 164008
 genomic_sequence:L03369 
 genomic_sequence:L03367 ; g157036
 genomic_sequence:L03368 ; g157038
 cDNA_sequence:L04964 ; g157041
 pr_sequence_SwissProt:Q03017 
 pr_sequence_PIR:A44269 
 pr_sequence_PIR:A44268 
 pr_sequence_PIR:B44268 
ems_allele:
cact1
cact2
cact3
cact4
cact5
cact6
cact7
cact8
cact9
cact10
cact11
cact12
cact13
cact14
cact15
cact16
cact17
cact18
cactAA51
cactAA58
cactAB10
cactAB13
cactSu
cactX6
cactY11
cactRN48
P_element_allele:
cact255
k17027 sequenced
k17003 sequenced
PM_dysgenesis_allele:
cact19
cact20
cact21
cact22
cactBQ
cactE10
cactE13
cactE15
cactE17
cactE19
cactE2
cactE20
cactE25
cactE29
cactE4
cactE6
cactE8
cactEP
cactP1
cactP3
cactP5
cactP6
cactP7
X_ray_allele:
cactE10R01
cactE10RJ1
misc_allele:
cact99
aberration_associated_allele:
cactchif64 (Df(2L)cact-255rv64)
Df(2L)H60-3
Df(2L)II30
Df(2L)III18
phenotypic_class: vital.
SM_notes: Translation from alignment of GenBank L04964.
k17027 & k17003 (66739) may be alleles of cact (66479-53838) since 260bp
upstream.
===========================================================================
\+symbol: anon-35F/36A
\+formal_name:  BG:DS02740 .16
synonym: un5
UID: FBgn0014092
references:
FBrf0055573 == Geisler et al., 1992, Cell 71: 613--621
cytology: 35F6--35F12
cytology_data: Left limit from molecular mapping relative to cni (FBrf0082538)
cytology_data: Right limit from molecular mapping relative to cact
(FBrf0055573)
genefinder: 25
genscan: 50
product: un5 (NGG-1 interacting factor 3, NIF3)
match_to: SP P53081 e-31 Y
match_to: GB W63821 e-25 M (Mus EST)
match_to: GB AA096836 e-25 M (Mus EST)
match_to: GB H15210 e-15 H (Hum EST)
match_to: GB H84119 e-15 H (Hum EST)
EST: LD28566.5'; CK01378.3'
P1: DS02740
direction: +
JR_notes: John Tower calls this P2A; between 1kb and 2kb from 5' end of cact.
Deletion excisions of k17027 are either cact- or 35Fe- (as predicted).
Neither are 35Fg- i.e. DS02740.16 is not 35Fg.
SM_notes: k17027 & k17003 (66739) may be alleles of this (67924-71177) but
far (1185bp away).
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
===========================================================================
\+symbol: l(2)35Fe
\+formal_name:  BG:DS02740 .17
name: lethal (2) 35Fe
synonym: Rpl4
UID: FBgn0001995
references:
cytology: 35F11--35F12
cytology_data: Left limit from in situ hybridisation (FBrf0067338)
cytology_data: Right limit from in situ hybridisation (FBrf0067338)
genefinder: 35
genscan: (42)
product: RPl4 (50S ribosomal protein L4)
match_to: TR O17005 e-47 W
match_to: SP P38516 e-23 B (50S ribosomal protein L4)
match_to: GB AA045589 e-21 H (Hum EST)
match_to: GB AA307866 e-28 H (Hum EST)
match_to: GB AA124364 e-31 M (Mus EST)
match_to: TR E1240162 e-8 A
match_to: TR E1240160 e-8 A
EST: LD33485.5'
P1: DS02740
direction: -
ems_allele:
l(2)35Fe1
P_element_allele:
l(2)35Fek14608 sequenced
phenotypic_class: vital; mitotic; polyploid cells Gatti.
SM_notes: Translation from alignment of partial(?) cDNA sequence from Ling
Hong
& Damon Harvey.
==========================================================================
\+symbol:  BG:DS02740 .18
\+formal_name:  BG:DS02740 .18
genefinder:
genscan: 336
product:
match_to:
EST:
P1: DS02740
direction: -
SM_notes: Translation from Genscan. Kerrie reports no PCR products after 2
attempts.
==========================================================================
\+symbol:  BG:DS02740 .19
\+formal_name:  BG:DS02740 .19
genefinder:
genscan: 205
product:
match_to:
EST:
P1: DS02740
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR products from GH(4)
and LP(2) libraries.
===========================================================================
\+symbol:  BG:DS09218 .1
\+formal_name:  BG:DS09218 .1
genefinder: 23
genscan: 52
product:
match_to:
EST:
P1: DS09218
direction: -
SM_notes: Translation from Genscan. Kerrie reports PCR products from LD
A8-F8 library(6).
==========================================================================
\+symbol: chif
\+formal_name:  BG:DS09218 .2
name: chiffon
UID: FBgn0000307
references:
FBrf0078863 == Landis and Tower, 1995, A. Conf. Dros. Res. 36: 118A
FBrf0054123 == Schupbach and Wieschaus, 1991, Genetics 129: 1119--1136
cytology: 35F6--36A2
cytology_data: Left limit from inclusion within Df(2L)cact-255rv64
(FBrf0058564)
cytology_data: Right limit from inclusion within Df(2L)RA5 (FBrf0051973)
genefinder: 44
genscan: 570
product:
match_to: TR E1288127 e-7 O (S. pombe)
EST: LD14373.3'; LD14373.5'; LD19808.5'; LD19808.3'; GM06264.5';
GM12481.5'; HL02831.5'; GH01539.3'; LD28038.5'
P1: DS09218
direction: -
ems_allele:
chif1
chif2
chif3
chif4
chifDB23
chifPS55
chifQY42
P_element_allele:
chifA507
n(2)k04216 sequenced
phenotypic_class: female_sterile.
JR_notes: k04216 is viable and fertile with chif.
SM_notes: Translation from alignment of cDNA from G. Landis and J. Tower.
k04216 inserted at 10147 of DS09218, LD19808.5' at 10154-9758, so P inserted
in first exon 7bp downstream of EST start.
===========================================================================
\+symbol:  BG:DS09218 .3
\+formal_name:  BG:DS09218 .3
genefinder: 39 (1 span)
genscan:
product:
match_to:
EST: LD12474.3'; LD12474.5'; LD27171.5'; LD33101.5';
P1: DS09218
direction: +
SM_notes: Translation from full-length LD12474 (no good ORF).
===========================================================================
\+symbol:  BG:DS09218 .4
\+formal_name:  BG:DS09218 .4
genefinder: 86
genscan: 179
product: protein disulfide isomerase
match_to: SP Q11067 e-112 W
match_to: SP Q15084 e-108 H
match_to: TR G2702281 e-70 A
match_to: GB W80331 e-42 M (Mus EST)
match_to: GB M76982 e-14 Y
match_to: GB X52313 e-14 Y
match_to: GB X54535 e-14 Y
EST: LD05503.3'; LD05503.5'; GM02162.5'; GM05173.5'; GM12483.5';
LD12134.5'; LD14462.5'; LD14683.5'; LD20301.5'; LD23109.5'; LD24243.5';
LD24557.5'; LD33982.5'; LD29677.5'; LD31351.5'; LD31057.5'; LD31108.5';
LD25852.5'; LD28038.5'
P1: DS09218
direction: -
SM_notes: Translation from full-length LD05503.
===========================================================================
\+symbol:  BG:DS09218 .5
\+formal_name:  BG:DS09218 .5
genefinder: 22
genscan: 78
product:
match_to: TR Q24622 e-12 O (D.pseudoobscura Toll)
EST:
P1: DS09218
direction: +
SM_notes: Translation from Genscan. Kerrie reports PCR product from LP(1)
library.
==========================================================================
\+symbol:  BG:DS02780 .1
\+formal_name:  BG:DS02780 .1
genefinder: 38
genscan: 125
product:
match_to: GB L25390 e-12 O (Dros. pseudoobscura Tl)
EST: CK01518.3'; CK01518.5'; GH08155.5'
P1: DS02780
direction: -
SM_notes: Translation from full-length CK01518.
===========================================================================
\+symbol: Idgf1
\+formal_name:  BG:DS02780 .5
genefinder: 31
genscan: 81
product: imaginal disc growth factor
match_to: TR Q23997 e-121 D
match_to: TR O15993 e-28 O (Penaeus japonicus)
match_to: TR Q13231 e-25 H
match_to: SP P36222 e-26 H
match_to: TR Q15749 e-26 H
match_to: SP Q62010 e-20 M
match_to: TR Q61362 e-20 M
match_to: SP Q11174 e-13 W
match_to: LD25940.5' e-34; LD12729.5' e-34; LD22916.5' e-34; LD30495.5'
e-34 etc.
EST: GM09616.5'; GH07837.5'; GH03533.5'; GH07581.5'; GH04843.3'
P1: DS02780
direction: +
SM_notes: Translation from ESTs (5' & 3' ends) and Genscan.
===========================================================================
\+symbol: Idgf2
\+formal_name:  BG:DS02780 .4
genefinder: 45
genscan: 101
product: imaginal disc growth factor
match_to: TR Q23997 e-121 D
match_to: TR O15993 e-28 O (Penaeus japonicus)
match_to: TR Q13231 e-25 H
match_to: SP P36222 e-26 H
match_to: TR Q15749 e-26 H
match_to: SP Q62010 e-20 M
match_to: TR Q61362 e-20 M
match_to: SP Q11174 e-13 W
match_to: LD25940.5' e-34; LD12729.5' e-34; LD22916.5' e-34; LD30495.5'
e-34 etc.
EST: GH12581.5'; HL02712.5'; GH02092.5'; GH02192.5'; GH05540.5';
GH06632.5'; GH07990.5'; GH10214.5'; GH12262.5'; GH15212.5'; LP05630.3'
P1: DS02780
direction: +
SM_notes: Translation from full-length GH12581.
===========================================================================
\+symbol: Idgf3
\+formal_name:  BG:DS02780 .2
genefinder: 45
genscan: 125
product: imaginal disc growth factor
match_to: TR Q23997 e-121 D
match_to: TR O15993 e-28 O (Penaeus japonicus)
match_to: TR Q13231 e-25 H
match_to: SP P36222 e-26 H
match_to: TR Q15749 e-26 H
match_to: SP Q62010 e-20 M
match_to: TR Q61362 e-20 M
match_to: LD25940.5' e-34; LD12729.5' e-34; LD22916.5' e-34; LD30495.5'
e-34 etc.
EST: CK00436.5'; CK00436.3'; GM05553.5'; GH07453.5'; GH09372.5'; GM04853.5'
P1: DS02780
direction: +
SM_notes: Translation from full-length CK00436.
===========================================================================
symbol: l(2)35Fg
UID: FBgn0015959
references:
cytology: 35F6--36A2
cytology_data: Left limit from inclusion within Df(2L)cact-255rv64
(FBrf0067338)
cytology_data: Right limit from inclusion within Df(2L)RA5 (FBrf0067338)
P_element_allele:
l(2)35Fgk08106
phenotypic_class: vital.
JR_notes: Defined by l(2)k08106, but multiple insert (two inserts in 35F).
===========================================================================
\+symbol: dac
\+formal_name:  BG:DS02780 .3
name: dachshund
synonym: l(2)36Ae
UID: FBgn0005677
references:
FBrf0075101 == Mardon et al., 1994, Development 120: 3473--3486
FBrf0087175 == Garrity et al., 1996, Cell 85(5): 639--650
FBrf0089691 == Huang and Kunes, 1996, Cell 86(3): 411--422
FBrf0091167 == Shen and Mardon, 1997, Development 124(1): 45--52
FBrf0092671 == Roush, 1997, Science 275(5300): 618--619
FBrf0092657 == Pignoni and Zipursky, 1997, Development 124(2): 271--278
cytology: 36A1--36A2
cytology_data: Left limit from in situ hybridisation (FBrf0067338)
cytology_data: Right limit from in situ hybridisation (FBrf0067338)
genefinder: 50
genscan: 123
product:
match_to:
EST:
P1: DS02780
direction: -
 cDNA_sequence:U19269 ; g624298; g624297; g624300; g624296; g624299
 pr_sequence_TREMBL:Q24027 
 pr_sequence_TREMBL:Q24028 
 pr_sequence_TREMBL:Q24029 
 pr_sequence_TREMBL:Q24030 
 pr_sequence_TREMBL:Q24031 
misc_allele:
dac2
dac3
dac5
dac6
dac7
dac8
dac9
P_element_allele:
dacrK364
phenotypic_class: vital; escapers with crippled legs
SM_notes: Only nucleotides 3037-4976 of gene. Translation from aligned
GenBank sequence U19269 .
===========================================================================
Genes whose status is uncertain, or have not been mapped though may be in
region.
===========================================================================
symbol: l(2)35Ab
UID: FBgn0013532
references:
FBrf0075330 == J. Roote, Personal communication to FlyBase, 16 November
1994
cytology: 35A3--35B1
cytology_data: Included in Df(2L)fn2
cytology_data: Not included in Df(2L)fn3
ems_allele:
l(2)35Ab1
phenotypic_notes: GR17 lethality.
status: uncertain.
===========================================================================
symbol:  snRNA:U5:35EF 
name: small nuclear RNA U5 at 35EF
UID: FBgn0003936
references:
FBrf0040068 == Saluz et al., 1983, Nucleic Acids Res. 11: 77--90
FBrf0048816 == Saluz et al., 1988, Nucleic Acids Res. 16: 3582
cytology: 35E1--35F12
cytology_data: Left limit from in situ hybridisation (FBrf0040068)
cytology_data: Right limit from in situ hybridisation (FBrf0040068)
product: snRNA-U5
===========================================================================
symbol: DopR
name: Dopamine receptor
synonym: Dop1
cytology: 35E--35F
 na_sequence:X77234 ; g479128
 na_sequence:U22106 ; g722319
 pr_sequence_SwissProt:P41596 
 pr_sequence_TREMBL:Q24038 
 pr_sequence_PIR:S68780 
 pr_sequence_PIR:S44275 
MA_notes: No match with BDGP sequences of X77234 via their BLAST server.
July 14 97.; Sima says may be DS05899.2.3
===========================================================================
symbol: Nc34CD
name: Neural conserved at 34CD
UID: FBgn0005690
references:
FBrf0054219 == Kokoza et al., 1991, Genetika, Moscow 27: 51--60
FBrf0056302 == Perelygina et al., 1992, Genetika, Moscow 28(3): 98--104
cytology: 34C1--34D8
misc_notes: said to encode 2, 1.5 and 1.2-kb transcripts.
status: uncertain.
e===========================================================================
symbol: fs(2)lto1
UID: FBgn0005615
synonym: PN48
references:
FBrf0049878 == Schupbach and Wieschaus, 1989, Genetics 121: 101--117
FBrf0054123 == Schupbach and Wieschaus, 1991, Genetics 129: 1119--1136
FBrf0089631 == Digilio et al., 1996, Dev. Biol. 178(1): 90--100
cytology: 35E6--36A7
ems_allele:
fs(2)lto11
phenotypic_class: female_sterile.
JR_notes: Fertile over A48, r10, osp29, cact225rv64 - the latter is Df
35F;36D
===========================================================================
symbol: bls
name: bractless
cytology: 35E6--36A7
phenotypic_notes: Lacks bracts on bristles.
JR_notes: Information from Lewis Held.
===========================================================================
symbol: ifx
references:
Verheyen et al., 1996, Genetics 144(3): 1127--1141
\*c 34C1--34D4
JR_notes: probably distal to region
JR_notes: semilethal over el88, complements b84h50
DOI
Related Publication(s)
Research paper
An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster. The Adh region.
Ashburner et al., 1999, Genetics 153(1): 179--219 [FBrf0111326]
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