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Reference Report
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| Citation | Milan, M., Cohen, S.M. (1999). Notch signaling is not sufficient to define the affinity boundary between dorsal and ventral compartments. Mol. Cell 4(6): 1073--1078. (Export to RIS) | ||
| FlyBase ID | FBrf0123138 | ||
| Publication Type | Research paper | ||
| PubMed ID | 10635331 | ||
| PubMed Abstract | The developing limbs of Drosophila are subdivided into distinct cells populations known as compartments. Short-range interaction between cells in adjacent compartments induces expression of signaling molecules at the compartment boundaries. In addition to serving as the sources of long-range signals, compartment boundaries prevent mixing of the adjacent cell populations. One model for boundary formation proposes that affinity differences between compartments are defined autonomously as one aspect of compartment-specific cell identity. An alternative is that the affinity boundary depends on signaling between compartments. Here, we present evidence that the dorsal selector gene apterous plays a role in establishing the dorsoventral affinity boundary that is independent of Notch-mediated signaling between dorsal and ventral cells. | ||
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| FB2013_03 | |||
| FB2013_02 | |||
| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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Parent Publication
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| Publication Type | Journal | ||
| Abbreviation | Mol. Cell | ||
| Title | Molecular Cell | ||
| Publication Year | 1997- | ||
| ISBN/ISSN | 1097-2765 1097-4164 | ||
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Data from Reference
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| Alleles (5)
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| Constructs (1)
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| Genes (5)
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| Insertions (2)
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