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| Citation | Wicker-Thomas, C., Jallon, J. (2000). Role of Enhancer of zeste on the production of Drosophila melanogaster pheromonal hydrocarbons. Naturwissenschaften 87(2): 76--79. (Export to RIS) | ||
| FlyBase ID | FBrf0125446 | ||
| Publication Type | Research paper | ||
| PubMed ID | 10663138 | ||
| PubMed Abstract | In a search for genes controlling the production of Drosophila melanogaster contact pheromones, the gene Enhancer of zeste [E(z)] was found to be one player. Flies mutant for either the amorphic or the antimorphic allele of E(z) showed a similar hydrocarbon phenotype as those with the overlapping Df lxd(15) deficiency: decreased amounts of total hydrocarbons and especially unsaturated ones in both sexes. The decrease in the level of D. melanogaster female sex pheromone 7,11-heptacosadiene was dramatic and was correlated with an increase in 7-heptacosene. Females mutant for a gain-of-function allele had increased amounts of total hydrocarbons with wild-type proportions of dienes. Thus the E(z) gene seems to affect hydrocarbon biosynthesis, especially its desaturation steps and even more so the female-specific desaturation step transforming 7-monoenic fatty acids to 7,11-dienic ones and leading to female pheromones. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Naturwissenschaften | ||
| Title | Naturwissenschaften | ||
| Publication Year | 1913- | ||
| ISBN/ISSN | 0028-1042 1432-1904 | ||
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Data from Reference
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| Aberrations (4)
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| Alleles (4)
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| Genes (1)
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