Reference Report

Reference
Citation	Burmester, T., Mink, M., Pal, M., Laszloffy, Z., Lepesant, J., Maroy, P. (2000). Genetic and molecular analysis in the 70CD region of the third chromosome of Drosophila melanogaster. Gene 246(1-2): 157--167. (Export to RIS)
FlyBase ID	FBrf0127030
Publication Type	Research paper
PubMed ID	10767537
PubMed Abstract	A collection of lethal and semi-lethal P-element insertions in the 70CD region of chromosome 3 of Drosophila melanogaster was used to investigate genes and gene arrangements by a combination of genetic, cytological, functional and molecular methods. The 12 lethal insertions studied fall into seven complementation groups of six genes. Lethal phases, expression patterns and other phenotypic aspects of these genes were determined. The genes and additional available sequences were placed on cloned genomic DNA fragments and arranged in an EcoRI map of 150kb that covers approximately the bands 70C7-8 to 70D1. Determination of deficiency breakpoints links the genetic, physical and molecular data. The sequences adjacent to seven independent P-element insertions were established after plasmid rescue or polymerase chain reaction. Similarity searches allowed the assignment of the P-element insertions to known mutations, expressed sequence tags, sequence tagged sites, or homologous genes of other species. Among these were identified a putative transacylase, a putative cell cycle gene, and the gene responsible for the dominant Polycomb-suppressor phenotype of devenir. The genomic sequence of the l(3)70Ca/b gene reveals a novel heat shock protein (hsc70Cb). l(3)70Da was identified as a member of the CDC48/PEX1 ATPase family and its coding sequence was determined.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Gene
Title	Gene
Publication Year	1976-
ISBN/ISSN	0378-1119
Data from Reference
Aberrations (7)
	Df(3L)D-1rv16 Df(3L)D-5rv6 Df(3L)fz-D21 Df(3L)fz-GF3b Df(3L)fz-GS1a Df(3L)fz-M21 Df(3L)J40
Alleles (38)
	btl^6-81 btl⁰⁰²⁰⁸ btl^dev1 btl^LG18 btl^LG19 btl^S084401 CG6650^S067006 Ecol\lacZ^btl-S084401 Ecol\lacZ^{Hsc70Cb-S004112} Ecol\lacZ^{Hsc70Cb-S031820} Ecol\lacZ^{Hsc70Cb-S064906} Ecol\lacZ^{Hsc70Cb-S134217} Ecol\lacZ^{Hsc70Cb-S148513} Ecol\lacZ^{hth-dtl-S132307b} Ecol\lacZ^S004108a Ecol\lacZ^S027714 Ecol\lacZ^S067006 Ecol\lacZ^S072613a Ecol\lacZ^S072613b Ecol\lacZ^S084807 Hsc70Cb¹ Hsc70Cb⁰⁰⁰⁸² Hsc70Cb⁰⁷⁶²¹ Hsc70Cb^S004112 Hsc70Cb^S031820 Hsc70Cb^S064906 Hsc70Cb^S132307a Hsc70Cb^S134217 Hsc70Cb^S134802 Hsc70Cb^S148513 l(3)j2E11^j2E11 l(3)S027714^S004108b l(3)S027714^S027714 l(3)S072613a^S072613a Pex1⁰²⁴⁰² Pex1^s4868 Pex1^S084807 Pex1^unspecified
Genes (13)
	btl CG6650 CG6661 D Ecol\lacZ endos Fbp1 Hsc70Cb l(3)j2E11 l(3)S027714 l(3)S072613a Pex1 Sox21b
Insertions (22)
	P{EP}CG6650^EP3653 P{lacW}btl^6-81 P{lacW}btl^S084401 P{lacW}endos^S067006 P{lacW}Hsc70Cb^S004112 P{lacW}Hsc70Cb^S031820 P{lacW}Hsc70Cb^S064906 P{lacW}Hsc70Cb^S134217 P{lacW}Hsc70Cb^S134802 P{lacW}Hsc70Cb^S148513 P{lacW}hth^dtl-S132307b P{lacW}l(3)j2E11^j2E11 P{lacW}l(3)S027714^S027714 P{lacW}l(3)S072613a^S072613a P{lacW}Pex1^s4868 P{lacW}Pex1^S084807 P{lacW}S004108a P{lacW}S072613b P{PZ}btl⁰⁰²⁰⁸ P{PZ}Hsc70Cb⁰⁰⁰⁸² P{PZ}Hsc70Cb⁰⁷⁶²¹ P{PZ}Pex1⁰²⁴⁰²