Reference Report

Reference
Citation	Sung, C., Robinow, S. (2000). Characterization of the regulatory elements controlling neuronal expression of the A-isoform of the ecdysone receptor gene of Drosophila melanogaster. Mech. Dev. 91(1-2): 237--248. (Export to RIS)
FlyBase ID	FBrf0127343
Publication Type	Research paper
PubMed ID	10704848
PubMed Abstract	During the development of the adult central nervous system (CNS) of the fruitfly Drosophila melanogaster, the A-isoform of the ecdysone receptor (EcR-A), a typical nuclear hormone receptor, is expressed at high levels in the Type II neurons, a set of neurons that die shortly after the emergence of the adult. To understand the role that transcriptional regulation of nuclear receptor genes plays in CNS development, we have dissected the region controlling the transcription of EcR-A by analyzing the ability of this region to drive the expression of reporter genes in transgenic animals. These analyses have demonstrated that the Type II neurons are a heterogeneous collection of neurons that utilize different regulatory elements to coordinate the expression of the same transcript.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Mech. Dev.
Title	Mechanisms of Development
Publication Year	1990-
ISBN/ISSN	0925-4773
Data from Reference
Alleles (12)
	Ecol\lacZ^EcR.ET-AG Ecol\lacZ^EcR.ET-GH Ecol\lacZ^EcR.PLZ-AB Ecol\lacZ^EcR.PLZ-AG Ecol\lacZ^EcR.PLZ-BD Ecol\lacZ^EcR.PLZ-DG Ecol\lacZ^Scer\UAS.cBa Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} Scer\GAL4^EcR.GET-AG Scer\GAL4^EcR.GET-BD Scer\GAL4^EcR.GET-CE w^+mC
Constructs (11)
	P{EcR.ET-AG-LacZ} P{EcR.ET-GH-LacZ} P{EcR.GET-AG-GAL4} P{EcR.GET-BD-GAL4} P{EcR.GET-CE-GAL4} P{EcR.PLZ-AB-LacZ} P{EcR.PLZ-AG-LacZ} P{EcR.PLZ-BD-LacZ} P{EcR.PLZ-DG-LacZ} P{UAS-lacZ.B} P{UAS-mCD8::GFP.L}
Genes (6)
	Ecol\lacZ EcR Mmus\Cd8a Scer\GAL4 T:Avic\GFP w
Sequence features (5)
	EcR_AB EcR_AG EcR_BD EcR_CE EcR_DG