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Teeter, K., Naeemuddin, M., Gasperini, R., Zimmerman, E., White, K.P., Hoskins, R., Gibson, G. (2000). Haplotype dimorphism in a SNP collection from Drosophila melanogaster.  J. exp. Zool. 288(1): 63--75.
FlyBase ID
FBrf0127357
Publication Type
Research paper
Abstract

A moderate resolution single nucleotide polymorphism (SNP) map of the genome of Drosophila melanogaster that is designed for use in quantitative genetic mapping is described. Seventeen approximately 500 nucleotide gene sequences spaced at 10 to 20 centimorgan intervals were combined with 49 shorter sequence tag sites (STSs) at 5 to 10 centimorgan intervals to generate a map that should not leave any gaps greater than one half of a chromosome arm when any two wild type lines are compared. Of 20 markers with sufficient polymorphism to construct haplotype cladograms, 13 showed evidence for two divergent classes of haplotype. The possible mechanisms for and implications of the unexpected finding that two thirds of all short gene sequences in D. melanogaster may be dimorphic are discussed, including the suggestion that admixture between two separate lineages may have been a major event in the history of the species.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. exp. Zool.
    Title
    Journal of Experimental Zoology
    Publication Year
    1904-2002
    ISBN/ISSN
    0022-104X
    Data From Reference