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Reference Report
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| Citation | Kozlova, T., Thummel, C.S. (2000). Steroid regulation of postembryonic development and reproduction in Drosophila. Trends Endocrinol. Metab. 11(7): 276--280. (Export to RIS) | ||
| FlyBase ID | FBrf0129910 | ||
| Publication Type | Review | ||
| PubMed ID | 10920384 | ||
| PubMed Abstract | Ecdysteroids trigger major developmental transitions in Drosophila, including larval molts and metamorphosis. Recent genetic studies strongly support a role for the Ecdysteroid receptor (EcR)/Ultraspiracle (USP) heterodimer as an ecdysteroid receptor at the onset of metamorphosis, functioning as both a transcriptional activator and repressor in vivo. Genetic analysis also indicates that USP, like its vertebrate homolog retinoid X receptor (RXR), might be involved in regulatory pathways independently of EcR. The ecdysteroid hierarchy was also shown recently to regulate Drosophila oogenesis and reproduction. | ||
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Trends Endocrinol. Metab. | ||
| Title | Trends in Endocrinology and Metabolism | ||
| Publication Year | 1989- | ||
| ISBN/ISSN | 1043-2760 | ||
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Data from Reference
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| Alleles (1)
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| Genes (13)
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