|Citation||Kozlova, T., Thummel, C.S. (2000). Steroid regulation of postembryonic development and reproduction in Drosophila. Trends Endocrinol. Metab. 11(7): 276--280. (Export to RIS)|
|PubMed Abstract||Ecdysteroids trigger major developmental transitions in Drosophila, including larval molts and metamorphosis. Recent genetic studies strongly support a role for the Ecdysteroid receptor (EcR)/Ultraspiracle (USP) heterodimer as an ecdysteroid receptor at the onset of metamorphosis, functioning as both a transcriptional activator and repressor in vivo. Genetic analysis also indicates that USP, like its vertebrate homolog retinoid X receptor (RXR), might be involved in regulatory pathways independently of EcR. The ecdysteroid hierarchy was also shown recently to regulate Drosophila oogenesis and reproduction.|
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|Language of Publication||English|
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|Abbreviation||Trends Endocrinol. Metab.|
|Title||Trends in Endocrinology and Metabolism|
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