Open Close
Reference
Citation
Kozlova, T., Thummel, C.S. (2000). Steroid regulation of postembryonic development and reproduction in Drosophila.  Trends Endocrinol. Metab. 11(7): 276--280.
FlyBase ID
FBrf0129910
Publication Type
Review
Abstract

Ecdysteroids trigger major developmental transitions in Drosophila, including larval molts and metamorphosis. Recent genetic studies strongly support a role for the Ecdysteroid receptor (EcR)/Ultraspiracle (USP) heterodimer as an ecdysteroid receptor at the onset of metamorphosis, functioning as both a transcriptional activator and repressor in vivo. Genetic analysis also indicates that USP, like its vertebrate homolog retinoid X receptor (RXR), might be involved in regulatory pathways independently of EcR. The ecdysteroid hierarchy was also shown recently to regulate Drosophila oogenesis and reproduction.

PubMed ID
PubMed Central ID
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Trends Endocrinol. Metab.
    Title
    Trends in Endocrinology and Metabolism
    Publication Year
    1989-
    ISBN/ISSN
    1043-2760
    Data From Reference
    Alleles (1)
    Genes (13)