Reference Report

Reference
Citation	Ruiz-Gomez, M., Coutts, N., Price, A., Taylor, M.V., Bate, M. (2000). Drosophila dumbfounded: a myoblast attractant essential for fusion. Cell 102(2): 189--198. (Export to RIS)
FlyBase ID	FBrf0130056
Publication Type	Research paper
PubMed ID	10943839
PubMed Abstract	Aggregation and fusion of myoblasts to form myotubes is essential for myogenesis in many organisms. In Drosophila the formation of syncytial myotubes is seeded by founder myoblasts. Founders fuse with clusters of fusion-competent myoblasts. Here we identify the gene dumbfounded (duf) and show that it is required for myoblast aggregation and fusion. duf encodes a member of the immunoglobulin superfamily of proteins that is an attractant for fusion-competent myoblasts. It is expressed by founder cells and serves to attract clusters of myoblasts from which myotubes form by fusion.
DOI
Related Publication(s)
Review	Paper alert. Jones, 2000, Curr. Opin. Genet. Dev. 10(5): 462 [FBrf0131033]
Erratum	Erratum. Drosophila Dumbfounded: A myoblast attractant essential for fusion. Ruiz-Gomez et al., 2001, Cell 104(1): following 172 [FBrf0133279]
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Cell
Title	Cell
Publication Year	1974-
ISBN/ISSN	0092-8674
Data from Reference
Aberrations (9)
	Df(1)N-8 Df(1)N-81k1 Df(1)rst2 Df(1)vt Df(1)w67k30 Df(1)w258-11 Df(1)w258-42 Dp(1;3)w^vco T(1;4)w^m258-18
Alleles (9)
	Ecol\lacZ^kirre-rP298 kirre^Scer\UAS.cRa N^+tCos479 Scer\GAL4^ap-md544 Scer\GAL4^Dll-md23 Scer\GAL4^twi.PB Scer\GAL4^wg.PM sing^unspecified w^+mC
Constructs (4)
	P{479BE} P{GAL4-twi.B} P{GAL4-wg.M} P{UAS-kirre.R}
Genes (14)
	Con Ecol\lacZ Fas2 kirre Kr Mhc N rst Scer\GAL4 sing slou vt w wg
Insertions (3)
	P{GawB}ap^md544 P{GawB}Dll^md23 P{PZ}rP298