|Citation||Aderem, A., Ulevitch, R.J. (2000). Toll-like receptors in the induction of the innate immune response. Nature 406(6797): 782--787. (Export to RIS)|
|PubMed Abstract||The innate immune response is the first line of defence against infectious disease. The principal challenge for the host is to detect the pathogen and mount a rapid defensive response. A group of proteins that comprise the Toll or Toll-like family of receptors perform this role in vertebrate and invertebrate organisms. This reflects a remarkable conservation of function and it is therefore not surprising that studies of the mechanism by which they act has revealed new and important insights into host defence.|
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|Language of Publication||English|
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