Reference Report

Reference
Citation	Pannuti, A., Lucchesi, J.C. (2000). Recycling to remodel: evolution of dosage-compensation complexes. Curr. Opin. Genet. Dev. 10(6): 644--650. (Export to RIS)
FlyBase ID	FBrf0132278
Publication Type	Review
PubMed ID	11088015
PubMed Abstract	In diploid species where sex determination involves heteromorphic sex chromosomes, a mechanism has evolved to compensate for gene-dosage differences in sex-linked genes between the sexes. This regulatory mechanism, which is based on chromatin remodeling, is the function of complexes that include components themselves involved in other cellular functions or with homologs that are involved in such functions. Directing these complexes to the correct chromosome in the appropriate sex relies on pioneer or novel components as well as on the presence of sequence-dependent target sites.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Curr. Opin. Genet. Dev.
Title	Current Opinion in Genetics and Development
Publication Year	1991-
ISBN/ISSN	0959-437X
Data from Reference
Genes (9)
	mle mof MRG15 msl-1 msl-2 msl-3 roX1 roX2 Tip60