Reference Report

Reference
Citation	Kopp, A., Duncan, I., Carroll, S.B. (2000). Genetic control and evolution of sexually dimorphic characters in Drosophila. Nature 408(6812): 553--559. (Export to RIS)
FlyBase ID	FBrf0132416
Publication Type	Research paper
PubMed ID	11117736
PubMed Abstract	Sexually dimorphic abdominal pigmentation and segment morphology evolved recently in the melanogaster species group of the fruitfly Drosophila. Here we show that these traits are controlled by the bric à brac [corrected] (bab) gene, which integrates regulatory inputs from the homeotic and sex-determination pathways. bab expression is modulated segment- and sex-specifically in sexually dimorphic species, but is uniform in sexually monomorphic species. We suggest that bab has an ancestral homeotic function, and that regulatory changes at the bab locus played a key role in the evolution of sexual dimorphism. Pigmentation patterns specified by bab affect mating preferences, suggesting that sexual selection has contributed to the evolution of bab regulation.
DOI
Related Publication(s)
Erratum	Genetic control and evolution of sexually dimorphic characters in Drosophila. Kopp et al., 2001, Nature 410(6828): 611 [FBrf0135359]
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Nature
Title	Nature
Publication Year	1869-
ISBN/ISSN	0028-0836
Data from Reference
Aberrations (6)
	Df(3L)Ar12-1 Df(3L)bab^Ar07 Df(3L)bab-PG Df(3R)dsx2D Df(3R)RS1-98 Df(3R)Ubx-RS4-8
Alleles (15)
	Abd-B^Mcp-1 Abd-B^Sab-1 bab1^Ar07 bab1^Scer\UAS.cGa bab2^4.Scer\UAS bab2^Ar07 bab2^ftz-f1-66.3 bi^omb-282 dsx¹ dsx¹⁸ Ecol\lacZ^{bab1-A128.1F3} Ecol\lacZ^{HCJ199.Scer\FRT} ftz-f1^66.3 Scer\GAL4^C-765 Scer\GAL4^pnr-MD237
Constructs (2)
	P{UAS-bab1.G} P{UAS-bab2.4}
Genes (9)
	abd-A Abd-B bab1 bab2 bi dsx Ecol\lacZ ftz-f1 Scer\GAL4
Insertions (7)
	P{(-FRT)lacZ.HP}Abd-B^HCJ199 P{GawB}C-765 P{GawB}pnr^MD237 P{lArB}bab1^A128.1F3 P{UAS-bab1.G}4-51 P{UAS-bab2.4}4-51 P{UAS-bab2.4}ftz-f1^66.3