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Citation
Kim, M.S., Smith, D.P. (2001). The invertebrate odorant-binding protein LUSH is required for normal olfactory behavior in Drosophila.  Chem. Senses 26(2): 195--200.
FlyBase ID
FBrf0134509
Publication Type
Research paper
Abstract

The invertebrate odorant-binding proteins consist of a large family of low-molecular-weight, highly divergent proteins expressed exclusively in the chemosensory sensilla of insects. Each member of this family studied to date is secreted into the sensillum lymph of a small subset of sensilla by non-neuronal support cells. These expression patterns suggests an odor-specific function for these proteins as opposed to a general role in sensillum biology. Consistent with this notion, mutants defective for LUSH, a Drosophila member of this family, have odor-specific defects in olfactory behavior. The Drosophila genome contains at least 32 members of this gene family, rivaling the number of odorant receptors in this species. The relationship between these two protein families and how they act to determine odor specificity of olfactory neurons will be the topic of future studies.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Chem. Senses
    Title
    Chemical Senses
    Publication Year
    1980-
    ISBN/ISSN
    0379-864X
    Data From Reference
    Genes (5)