Reference Report

Reference
Citation	Chung, Y.D., Zhu, J., Han, Y.G., Kernan, M.J. (2001). nompA encodes a PNS-specific, ZP domain protein required to connect mechanosensory dendrites to sensory structures. Neuron 29(2): 415--428. (Export to RIS)
FlyBase ID	FBrf0134806
Publication Type	Research paper
PubMed ID	11239432
PubMed Abstract	Mutations in the no-mechanoreceptor-potential A (nompA) gene, which eliminate transduction in Drosophila mechanosensory organs, disrupt contacts between neuronal sensory endings and cuticular structures. nompA encodes a transmembrane protein with a large, modular extracellular segment that includes a zona pellucida (ZP) domain and several plasminogen N-terminal (PAN) modules. It is specifically expressed in type I sense organs of the peripheral nervous system by the support cells that ensheath the neuronal sensory process. A green fluorescent protein (GFP)-NompA fusion protein is localized to the dendritic cap, an extracellular matrix that covers the ciliary outer segment of the sensory process and that shows organizational defects in nompA mutants. The structure and location of NompA suggest that it forms part of a mechanical linkage required to transmit mechanical stimuli to the transduction apparatus.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Neuron
Title	Neuron
Publication Year	1988-
ISBN/ISSN	0896-6273
Data from Reference
Aberrations (2)
	Df(2R)27 Df(2R)vg135
Alleles (9)
	Avic\GFP^Scer\UAS.cUa Fpps^k06103 nompA¹ nompA² nompA^+t10.2 nompA^T:Avic\GFP nompA^vg135 Scer\GAL4^MJ94 shn⁰⁴⁷³⁸
Constructs (3)
	P{nompA.10.2} P{nompA.GFP} P{UAS-GFP.U}
Genes (15)
	Avic\GFP CG7741 CG7745 CG17111 CG42326 Fpps mey neo nompA nyo Or47b Scer\GAL4 shn T:Avic\GFP tyn
Insertions (6)
	P{en-lacZ(wXba)}9 P{GawB}MJ94 P{lacW}Fpps^k06103 P{PZ}shn⁰⁴⁷³⁸ P{wE}8 roo{}nompA^vg135