A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

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Reference
Citation Azou, Y., Bregliano, J.C. (2001). I-R system of hybrid dysgenesis in Drosophila melanogaster: analysis of the mitochondrial DNA in reactive strains exhibiting different potentials for I factor transposition.  Heredity 86(1): 110--116. (Export to RIS)
FlyBase ID FBrf0135828
Publication Type Research paper
PubMed ID 11298822
PubMed Abstract In the I-R hybrid dysgenesis system, Drosophila melanogaster strains fall into two categories denoted inducer (I) and reactive (R). Among the reactive strains we can distinguish strains with weak, medium or strong reactivity levels. These levels are inherited in a complex way involving both chromosomal and nonchromosomal determinants, the nonchromosomal determinant being mainly maternally inherited. We were interested in determining the molecular basis of this maternal transmission. In this article we analyse the possible implication of the mitochondrial DNA in the determination of the reactivity levels. The mtDNA was analysed in lines with very different reactivity levels with the aim of correlating sequence differences with reactivity levels. The mtDNA was analysed by sequencing and restriction fragment length. No correlation was established between reactivity level and mtDNA sequence. This may favour the hypothesis that epigenetic changes would be responsible for the different reactivity levels and their transgenerational transmission.
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Language of Publication English
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Publication Type Journal
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Title Heredity
Publication Year 1947-
ISBN/ISSN 0018-067X
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